Morphology of the patent ductus arteriosus does not preclude successful patent ductus arteriosus stent implantation in high-risk patients undergoing hybrid stage I palliation: Recommendations to optimize ductal stent positioning

Author(s):  
Michael R. Recto ◽  
Sandy Doyle ◽  
Vitor C. Guerra ◽  
Song Gui Yang ◽  
Thomas Yeh
2020 ◽  
Vol 41 (4) ◽  
pp. 837-842
Author(s):  
Paulo Valderrama ◽  
Francisco Garay ◽  
Daniel Springmüller ◽  
Yeny Briones ◽  
Daniel Aguirre ◽  
...  

2011 ◽  
Vol 67 (2) ◽  
pp. 171-173 ◽  
Author(s):  
Prabhat Kumar ◽  
R Datta ◽  
R Nair ◽  
G Sridhar

2011 ◽  
Vol 32 (4) ◽  
pp. 413-417 ◽  
Author(s):  
Matthew J. Egan ◽  
Aaron J. Trask ◽  
Peter B. Baker ◽  
Jonathan Lawrence ◽  
Elena Ladich ◽  
...  

PLoS ONE ◽  
2021 ◽  
Vol 16 (6) ◽  
pp. e0252897
Author(s):  
Thaer S. A. Abdalla ◽  
Jan Meiners ◽  
Sabine Riethdorf ◽  
Alexandra König ◽  
Nathaniel Melling ◽  
...  

Colorectal cancer (CRC) is one of the leading causes of cancer death worldwide. There is an urgent need to identify prognostic markers for patients undergoing curative resection of CRC. The detection of circulating tumor cells in peripheral blood is a promising approach to identify high-risk patients with disseminated disease in colorectal cancer. This study aims to evaluate the prognostic relevance of preoperative CTCs using the Cellsearch® system (CS) in patients, who underwent resection with curative intent of different stages (UICC I-IV) of colorectal cancer. Out of 91 Patients who underwent colorectal resection, 68 patients were included in this study. CTC analysis was performed in patients with CRC UICC stages I-IV immediately before surgery. Data were correlated with clinicopathological parameters and patient outcomes. One or more CTCs/7.5 mL were detected in 45.6% (31/68) of patients. CTCs were detected in all stages of the Union of International Cancer Control (UICC), in stage I (1/4, 25%), in stage II (4/12, 33.3%), in stage III (5/19, 26.3%) and in stage IV (21/33, 63.6%). The detection of ≥ 1 CTCs/ 7.5ml correlated to the presence of distant overt metastases (p = 0.014) as well as with shorter progression-free (p = 0.008) and overall survival (p = 0.008). Multivariate analyses showed that the detection of ≥ 1 CTCs/ 7.5ml is an independent prognostic indicator for overall survival (HR, 3.14; 95% CI, 1.18–8.32; p = 0.021). The detection of CTCs is an independent and strong prognostic factor in CRC, which might improve the identification of high-risk patients in future clinical trials.


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