Short and long term complications of device closure of atrial septal defect and patent foramen ovale: Meta-analysis of 28,142 patients from 203 studies

2013 ◽  
Vol 82 (7) ◽  
pp. 1123-1138 ◽  
Author(s):  
Adnan Abaci ◽  
Serkan Unlu ◽  
Yakup Alsancak ◽  
Ulker Kaya ◽  
Burak Sezenoz
Keyword(s):  
Atrial Septal Defect ◽  
Patent Foramen Ovale ◽  
Septal Defect ◽  
Meta Analysis ◽  
Foramen Ovale ◽  
Device Closure ◽  
Short And Long Term

scholarly journals Short- and long-term haemodynamic consequences of transcatheter closure of atrial septal defect and patent foramen ovale

2021 ◽  
Author(s):  
X. Jin ◽  
Y. M. Hummel ◽  
W. T. Tay ◽  
J. F. Nauta ◽  
N. S. S. Bamadhaj ◽  
...  
Keyword(s):  
Atrial Septal Defect ◽  
Diastolic Function ◽  
Patent Foramen Ovale ◽  
Septal Defect ◽  
Transcatheter Closure ◽  
Foramen Ovale ◽  
Short And Long Term ◽  
Interatrial Shunt ◽  
Pfo Closure

Abstract Background Transcatheter atrial septal defect (ASD) and patent foramen ovale (PFO) closure might have opposite short- and long-term haemodynamic consequences compared with restricted interatrial shunt creation, which recently emerged as a potential treatment modality for patients with heart failure with preserved ejection fraction (HFpEF). Given the opposing approaches of ASD and PFO closure versus shunt creation, we investigated the early and sustained cardiac structural and functional changes following transcatheter ASD or PFO closure. Methods In this retrospective study, adult secundum-type ASD and PFO patients with complete echocardiography examinations at baseline and at 1‑day and 1‑year follow-up who also underwent transcatheter closure between 2013 and 2017 at the University Medical Centre Groningen, the Netherlands were included. Results Thirty-nine patients (mean age 48 ± standard deviation 16 years, 61.5% women) were included. Transcatheter ASD/PFO closure resulted in an early and persistent decrease in right ventricular systolic and diastolic function. Additionally, transcatheter ASD/PFO closure resulted in an early and sustained favourable response of left ventricular (LV) systolic function, but also in deterioration of LV diastolic function with an increase in LV filling pressure (LVFP), as assessed by echocardiography. Age (β = 0.31, p = 0.009) and atrial fibrillation (AF; β = 0.24, p = 0.03) were associated with a sustained increase in LVFP after transcatheter ASD/PFO closure estimated by mean E/e’ ratio (i.e. ratio of mitral peak velocity of early filling to diastolic mitral annular velocity). In subgroup analysis, this was similar for ASD and PFO closure. Conclusion Older patients and patients with AF were predisposed to sustained increases in left-sided filling pressures resembling HFpEF following ASD or PFO closure. Consequently, these findings support the current concept that creating a restricted interatrial shunt might be beneficial, particularly in elderly HFpEF patients with AF.

scholarly journals Long-term complications evidenced studying the explanted Gore® HELEX® atrial septal defect occluder seven years after implantation: a case report

2017 ◽  
Vol 26 (2) ◽  
pp. 105
Author(s):  
Jurijs Sekretarjovs ◽  
Mārtiņš Kalējs ◽  
Ainārs Rudzītis ◽  
Ivars Brečs ◽  
Hermanis Sorokins ◽  
...  
Keyword(s):  
Atrial Septal Defect ◽  
Patent Foramen Ovale ◽  
Septal Defect ◽  
Giant Cells ◽  
Myocardial Cells ◽  
Foramen Ovale ◽  
Atrial Septal Defect Closure ◽  
Foreign Body Giant Cells ◽  
Enhanced Expression

We present the results of the first morphological study of a Gore® HELEX® Septal Occluder 30 mm that was explanted seven years after interventional implantation due to a significant left-to-right shunt (7 mm) which resulted from the stretching of the concomitant patent foramen ovale by the occluder after atrial septal defect closure. Complete endothelialization of the surface of the device, the formation of the connective tissue around the implant, minor chronic inflammation, the appearance of foreign body giant cells and weakened myocardial cells adjacent to the implant as well as enhanced expression of matrix metalloproteinases were demonstrated.

Percutaneous device closure of atrial septal defect and patent foramen ovale

2010 ◽  
pp. 632-652
Author(s):  
Patrick A. Calvert ◽  
Bushra S. Rana ◽  
David Hildick-Smith
Keyword(s):  
Atrial Septal Defect ◽  
Patent Foramen Ovale ◽  
Septal Defect ◽  
Interventional Procedure ◽  
Structural Heart Disease ◽  
Foramen Ovale ◽  
Device Closure ◽  
The United Kingdom ◽  
Clinical Benefits ◽  
Asd Closure

Structural heart disease interventions look set to form an increasing proportion of the interventional cardiologist’s workload. Device closure of atrial septal connections, both patent foramen ovale (PFO) and atrial septal defect (ASD), are the most commonly performed adult structural interventional procedure in the United Kingdom, with 793 PFO and 573 ASD closure procedures performed in adults in 2007. Device closure of ASDs and PFOs are elegant procedures which combine technical and imaging skills with a detailed understanding of cardiac anatomy. More importantly, they also provide tangible clinical benefits to patients.

Atrial septal defect and patent foramen ovale: early and long-term effects on endothelial function after percutaneous occlusion procedure

2019 ◽  
Vol 34 (9) ◽  
pp. 1499-1508 ◽  
Author(s):  
Pietro Scicchitano ◽  
Michele Gesualdo ◽  
Francesca Cortese ◽  
Tommaso Acquaviva ◽  
Emanuela de Cillis ◽  
...  
Keyword(s):  
Endothelial Function ◽  
Atrial Septal Defect ◽  
Patent Foramen Ovale ◽  
Septal Defect ◽  
Foramen Ovale ◽  
Long Term Effects

Amplatzer occluder versus CardioSEAL/STARFlex occluder: a meta-analysis of the efficacy and safety of transcatheter occlusion for patent foramen ovale and atrial septal defect

2012 ◽  
Vol 23 (4) ◽  
pp. 582-596 ◽  
Author(s):  
Yifei Li ◽  
Kaiyu Zhou ◽  
Yimin Hua ◽  
Chuan Wang ◽  
Liang Xie ◽  
...  
Keyword(s):  
Confidence Interval ◽  
Atrial Septal Defect ◽  
Patent Foramen Ovale ◽  
Septal Defect ◽  
Meta Analysis ◽  
World Health ◽  
Cochrane Central Register ◽  
Foramen Ovale ◽  
Transcatheter Occlusion ◽  
Significant Difference

AbstractObjectivePercutaneous transcatheter occlusion has benefited thousands of patients suffering from patent foramen ovale and atrial septal defect. However, no general agreement has been reached on the superiority among occluders. Thus, a meta-analysis between the two most commonly adopted types of occluders was conducted.MethodsThe literature review has identified relevant studies up to May, 2011 in the databases of PubMed, EMBASE, the Cochrane Central Register of Controlled Trials, and World Health Organization clinical trials registry centre. Meta-analysis was performed in a fixed/random effects model using Revman 5.1.1. Information on complications and outcomes was extracted.ResultsAnalysis from included studies reports an outcome in favour of the Amplatzer. The Amplatzer has proven its superiority in efficacy with a significantly lower risk of early (95% confidence interval = 0.09–0.34) and long-term (95% confidence interval = 0.14–0.97) residual shunt rate for atrial septal defect occlusion, although no significant difference in performance has been reported for patent foramen ovale. In addition, the Amplatzer has also remarkably reduced the risk of embolisation by the device (95% confidence interval = 0.07–0.45) for atrial septal defect and new-set atrial fibrillation (95% confidence interval = 0.18–0.48) for patent foramen ovale. On evaluation of recurrent thrombotic events, it was found that the Amplatzer greatly lowered the rate of thrombus formation on the device (95% confidence interval = 0.02–0.21) for patent foramen ovale; however, no statistical difference was found on atrial septal defect evaluation. However, the result indicated no statistically significant difference between the two kinds of occluders in stroke and transient ischaemic attack of patent foramen ovale.ConclusionThe meta-analysis has proven the Amplatzer to be the superior occluder, serving better prognosis with more fluent procedure and less complications.

Paradoxical Emboli in Children and Young Adults: Role of Atrial Septal Defect and Patent Foramen Ovale Device Closure

2006 ◽  
Vol 81 (5) ◽  
pp. 615-618 ◽  
Author(s):  
Peter J. Bartz ◽  
Frank Cetta ◽  
Allison K. Cabalka ◽  
Guy S. Reeder ◽  
Umberto Squarcia ◽  
...  
Keyword(s):  
Young Adults ◽  
Atrial Septal Defect ◽  
Patent Foramen Ovale ◽  
Septal Defect ◽  
Foramen Ovale ◽  
Device Closure ◽  
Paradoxical Emboli ◽  
Children And Young Adults
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