Three-dimensional and quantitative analysis of atherosclerotic plaque composition by automated differential echogenicity

2007 ◽  
Vol 70 (7) ◽  
pp. 968-978 ◽  
Author(s):  
Nico Bruining ◽  
Stefan Verheye ◽  
Michiel Knaapen ◽  
Pamela Somers ◽  
Jos R.T.C. Roelandt ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Atherosclerotic Plaque ◽  
Three Dimensional ◽  
Plaque Composition

scholarly journals High-resolution, multicontrast three-dimensional-MRI characterizes atherosclerotic plaque composition in ApoE-/- mice ex vivo

2004 ◽  
Vol 20 (6) ◽  
pp. 981-989 ◽  
Author(s):  
J�rgen E. Schneider ◽  
Martina A. McAteer ◽  
Damian J. Tyler ◽  
Kieran Clarke ◽  
Keith M. Channon ◽  
...  
Keyword(s):  
High Resolution ◽  
Atherosclerotic Plaque ◽  
Ex Vivo ◽  
Three Dimensional ◽  
Plaque Composition

Study on erythrocytes by SEM photogrammetry (SEMP) technique

1990 ◽  
Vol 48 (3) ◽  
pp. 724-725
Author(s):  
Tong Wensheng ◽  
Lu Lianhuang ◽  
Zhang Zhijun
Keyword(s):  
Quantitative Analysis ◽  
Cell Membrane ◽  
Clinical Diagnosis ◽  
Human Body ◽  
Blood Cells ◽  
Three Dimensional ◽  
Normal Person ◽  
Blood Disease ◽  
Computation Technique ◽  
Important Basis

This is a combined study of two diffirent branches, photogrammetry and morphology of blood cells. The three dimensional quantitative analysis of erythrocytes using SEMP technique, electron computation technique and photogrammetry theory has made it possible to push the study of mophology of blood cells from LM, TEM, SEM to a higher stage, that of SEM P. A new path has been broken for deeply study of morphology of blood cells.In medical view, the abnormality of the quality and quantity of erythrocytes is one of the important changes of blood disease. It shows the abnormal blood—making function of the human body. Therefore, the study of the change of shape on erythrocytes is the indispensable and important basis of reference in the clinical diagnosis and research of blood disease.The erythrocytes of one normal person, three PNH Patients and one AA patient were used in this experiment. This research determines the following items: Height;Length of two axes (long and short), ratio; Crevice in depth and width of cell membrane; Circumference of erythrocytes; Isoline map of erythrocytes; Section map of erythrocytes.

scholarly journals Temporal and spatial changes in wall shear stress during atherosclerotic plaque progression in mice

2018 ◽  
Vol 5 (3) ◽  
pp. 171447 ◽  
Author(s):  
R. Xing ◽  
A. M. Moerman ◽  
Y. Ridwan ◽  
M. J. Daemen ◽  
A. F. W. van der Steen ◽  
...  
Keyword(s):  
Shear Stress ◽  
Wall Shear Stress ◽  
Mouse Model ◽  
Atherosclerotic Plaque ◽  
Proximal Part ◽  
Plaque Progression ◽  
Plaque Composition ◽  
Spatial Changes ◽  
Temporal And Spatial ◽  
Wall Shear

Wall shear stress (WSS) is involved in atherosclerotic plaque initiation, yet its role in plaque progression remains unclear. We aimed to study (i) the temporal and spatial changes in WSS over a growing plaque and (ii) the correlation between WSS and plaque composition, using animal-specific data in an atherosclerotic mouse model. Tapered casts were placed around the right common carotid arteries (RCCA) of ApoE −/− mice. At 5, 7 and 9 weeks after cast placement, RCCA geometry was reconstructed using contrast-enhanced micro-CT. Lumen narrowing was observed in all mice, indicating the progression of a lumen intruding plaque. Next, we determined the flow rate in the RCCA of each mouse using Doppler Ultrasound and computed WSS at all time points. Over time, as the plaque developed and further intruded into the lumen, absolute WSS significantly decreased. Finally at week 9, plaque composition was histologically characterized. The proximal part of the plaque was small and eccentric, exposed to relatively lower WSS. Close to the cast a larger and concentric plaque was present, exposed to relatively higher WSS. Lower WSS was significantly correlated to the accumulation of macrophages in the eccentric plaque. When pooling data of all animals, correlation between WSS and plaque composition was weak and no longer statistically significant. In conclusion, our data showed that in our mouse model absolute WSS strikingly decreased during disease progression, which was significantly correlated to plaque area and macrophage content. Besides, our study demonstrates the necessity to analyse individual animals and plaques when studying correlations between WSS and plaque composition.

Sight distance red zones on combined horizontal and sag vertical curves

1998 ◽  
Vol 25 (4) ◽  
pp. 621-630 ◽  
Author(s):  
Yasser Hassan ◽  
Said M Easa
Keyword(s):  
Quantitative Analysis ◽  
Three Dimensional ◽  
The Other ◽  
Two Dimensional ◽  
Horizontal Curve ◽  
Sight Distance ◽  
Stopping Sight Distance ◽  
Three Dimensional Models ◽  
Highway Alignment ◽  
Current Standards

Coordination of highway horizontal and vertical alignments is based on subjective guidelines in current standards. This paper presents a quantitative analysis of coordinating horizontal and sag vertical curves that are designed using two-dimensional standards. The locations where a horizontal curve should not be positioned relative to a sag vertical curve (called red zones) are identified. In the red zone, the available sight distance (computed using three-dimensional models) is less than the required sight distance. Two types of red zones, based on stopping sight distance (SSD) and preview sight distance (PVSD), are examined. The SSD red zone corresponds to the locations where an overlap between a horizontal curve and a sag vertical curve should be avoided because the three-dimensional sight distance will be less than the required SSD. The PVSD red zone corresponds to the locations where a horizontal curve should not start because drivers will not be able to perceive it and safely react to it. The SSD red zones exist for practical highway alignment parameters, and therefore designers should check the alignments for potential SSD red zones. The range of SSD red zones was found to depend on the different alignment parameters, especially the superelevation rate. On the other hand, the results showed that the PVSD red zones exist only for large values of the required PVSD, and therefore this type of red zones is not critical. This paper should be of particular interest to the highway designers and professionals concerned with highway safety.Key words: sight distance, red zone, combined alignment.

scholarly journals Quantitative analysis of normal fetal brain volume and flow by three-dimensional power Doppler ultrasound

2013 ◽  
Vol 76 (9) ◽  
pp. 504-509 ◽  
Author(s):  
Ju-Chun Hsu ◽  
Yi-Cheng Wu ◽  
Peng-Hui Wang ◽  
Hsing-I Wang ◽  
Chi-Mou Juang ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Doppler Ultrasound ◽  
Brain Volume ◽  
Power Doppler ◽  
Three Dimensional ◽  
Fetal Brain ◽  
Power Doppler Ultrasound

Quantitative analysis of the three dimensional fetoplacental vascular tree in normal, term placenta

Placenta ◽  
2017 ◽  
Vol 57 ◽  
pp. 239-240 ◽  
Author(s):  
Andrew Melbourne ◽  
Rosalind Pratt ◽  
Ciaran Hutchinson ◽  
Owen Arthurs ◽  
Neil J. Sebire ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Three Dimensional ◽  
Vascular Tree ◽  
Term Placenta ◽  
Normal Term
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