Outcome of patients with acute coronary syndromes and moderate coronary lesions undergoing deferral of revascularization based on fractional flow reserve assessment

2006 ◽  
Vol 68 (4) ◽  
pp. 544-548 ◽  
Author(s):  
Joshua J. Fischer ◽  
Xin-Qun Wang ◽  
Habib Samady ◽  
Ian J. Sarembock ◽  
Eric R. Powers ◽  
...  
Keyword(s):  
Fractional Flow Reserve ◽  
Acute Coronary Syndromes ◽  
Fractional Flow ◽  
Flow Reserve ◽  
Coronary Syndromes ◽  
Coronary Lesions

Clinical and prognostic value of poststenting fractional flow reserve in acute coronary syndromes

Heart ◽  
2016 ◽  
Vol 102 (24) ◽  
pp. 1988-1994 ◽  
Author(s):  
Srikanth Kasula ◽  
Shiv Kumar Agarwal ◽  
Yalcin Hacioglu ◽  
Nagavenkata Krishnachand Pothineni ◽  
Sabha Bhatti ◽  
...  
Keyword(s):  
Fractional Flow Reserve ◽  
Acute Coronary Syndromes ◽  
Prognostic Value ◽  
Fractional Flow ◽  
Flow Reserve ◽  
Coronary Syndromes

scholarly journals Virtual (Computed) Fractional Flow Reserve: Future Role in Acute Coronary Syndromes

2021 ◽  
Vol 8 ◽  
Author(s):  
Hazel Arfah Haley ◽  
Mina Ghobrial ◽  
Paul D. Morris ◽  
Rebecca Gosling ◽  
Gareth Williams ◽  
...  
Keyword(s):  
Fractional Flow Reserve ◽  
Acute Coronary Syndromes ◽  
Visual Assessment ◽  
Fractional Flow ◽  
Acute Setting ◽  
Mild Disease ◽  
Flow Reserve ◽  
Pressure Wire ◽  
Coronary Syndromes ◽  
St Elevation

The current management of acute coronary syndromes (ACS) is with an invasive strategy to guide treatment. However, identifying the lesions which are physiologically significant can be challenging. Non-invasive imaging is generally not appropriate or timely in the acute setting, so the decision is generally based upon visual assessment of the angiogram, supplemented in a small minority by invasive pressure wire studies using fractional flow reserve (FFR) or related indices. Whilst pressure wire usage is slowly increasing, it is not feasible in many vessels, patients and situations. Limited evidence for the use of FFR in non-ST elevation (NSTE) ACS suggests a 25% change in management, compared with traditional assessment, with a shift from more to less extensive revascularisation. Virtual (computed) FFR (vFFR), which uses a 3D model of the coronary arteries constructed from the invasive angiogram, and application of the physical laws of fluid flow, has the potential to be used more widely in this situation. It is less invasive, fast and can be integrated into catheter laboratory software. For severe lesions, or mild disease, it is probably not required, but it could improve the management of moderate disease in 'real time' for patients with non-ST elevation acute coronary syndromes (NSTE-ACS), and in bystander disease in ST elevation myocardial infarction. Its practicability and impact in the acute setting need to be tested, but the underpinning science and potential benefits for rapid and streamlined decision-making are enticing.

scholarly journals Fractional Flow Reserve in Acute Coronary Syndromes ∗

2016 ◽  
Vol 68 (11) ◽  
pp. 1192-1194 ◽  
Author(s):  
William F. Fearon ◽  
Bernard De Bruyne ◽  
Nico H.J. Pijls
Keyword(s):  
Fractional Flow Reserve ◽  
Acute Coronary Syndromes ◽  
Fractional Flow ◽  
Flow Reserve ◽  
Coronary Syndromes
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