What are the benefits and harms of vasodilators for people with primary or secondary Raynaud's phenomenon?

2021 ◽  
Author(s):  
Sera Tort ◽  
Jane Burch
Keyword(s):  
Raynaud’S Phenomenon ◽  
Raynaud's Phenomenon ◽  
Secondary Raynaud’S Phenomenon

scholarly journals Efficacy of tadalafil in secondary Raynaud’s phenomenon resistant to vasodilator therapy: a double-blind randomized cross-over trial

Rheumatology ◽  
2010 ◽  
Vol 49 (12) ◽  
pp. 2420-2428 ◽  
Author(s):  
Padmanabha D. Shenoy ◽  
Sudeep Kumar ◽  
Lalan K. Jha ◽  
Sunil K. Choudhary ◽  
Uttam Singh ◽  
...  
Keyword(s):  
Raynaud’S Phenomenon ◽  
Raynaud's Phenomenon ◽  
Double Blind ◽  
Vasodilator Therapy ◽  
Secondary Raynaud’S Phenomenon

scholarly journals Aminaphtone Efficacy in Primary and Secondary Raynaud’s Phenomenon: A Feasibility Study

2019 ◽  
Vol 10 ◽  
Author(s):  
Barbara Ruaro ◽  
Carmen Pizzorni ◽  
Sabrina Paolino ◽  
Elisa Alessandri ◽  
Alberto Sulli
Keyword(s):  
Feasibility Study ◽  
Raynaud’S Phenomenon ◽  
Raynaud's Phenomenon ◽  
Secondary Raynaud’S Phenomenon

Hemorheological profile in primary and secondary Raynaud's phenomenon. Influence of microangiopathy

2014 ◽  
Vol 56 (3) ◽  
pp. 259-264 ◽  
Author(s):  
Amparo Vayá ◽  
Rafael Alis ◽  
Marco Romagnoli ◽  
Jose Todolí ◽  
Javier Calvo ◽  
...  
Keyword(s):  
Raynaud’S Phenomenon ◽  
Raynaud's Phenomenon ◽  
Secondary Raynaud’S Phenomenon

The effects of a single carbon dioxide and hot water hand bath on acral perfusion in systemic sclerosis: A randomized, clinical study

2019 ◽  
Vol 4 (2) ◽  
pp. 160-162
Author(s):  
Uwe Lange ◽  
Stephanie Bogensperger ◽  
Ingo H Tarner ◽  
Ulf Müller-Ladner
Keyword(s):  
Carbon Dioxide ◽  
Systemic Sclerosis ◽  
Clinical Study ◽  
Raynaud’S Phenomenon ◽  
Raynaud's Phenomenon ◽  
Hot Water ◽  
Control Group ◽  
Randomized Clinical Study ◽  
Vasoactive Medication ◽  
Secondary Raynaud’S Phenomenon

Secondary Raynaud’s phenomenon is the most common manifestation of systemic sclerosis, affecting more than 99% of systemic sclerosis patients, and a major cause of morbidity. Frequent and prolonged secondary Raynaud’s phenomenon attacks not only cause severe discomfort and pain but also ischemic acral tissue damage. In addition to vasoactive drugs, carbon dioxide (CO2) hand bath and hot water bath are potential non-pharmacological treatment options which can be self-administered by affected patients at any time. In order to compare the efficacy of these two physical measures, this randomized, clinical study evaluated the effects of a single CO2 hand bath in patients with systemic sclerosis and secondary Raynaud’s phenomenon and a healthy control group versus a single hot water hand bath on acral perfusion in systemic sclerosis by Doppler ultrasonography. None of the patients had currently digital ulcers, a vasoactive medication or a concomitant vascular disease. CO2 immersion induced an acute hemodynamic response, whereas hot water immersion had no significant effect on acral perfusion in systemic sclerosis.

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