For adults who have undergone general anesthesia, what are the effects of postoperative antiemetic drugs?

2020 ◽  
Author(s):  
Jane Burch ◽  
Ulrich Ronellenfitsch
Keyword(s):  
General Anesthesia ◽  
Antiemetic Drugs

scholarly journals Aggressive Prophylactic Treatments for Postoperative Nausea and Vomiting Improve Outcomes in Pediatric Adenotonsillectomy Procedure

2020 ◽  
Vol 25 (4) ◽  
pp. 303-308
Author(s):  
Tatyana Demidovich ◽  
Orlando Perez-Franco ◽  
Marco Silvestrini-Suarez ◽  
Pin Yue
Keyword(s):  
Risk Factors ◽  
High Risk ◽  
General Anesthesia ◽  
Postoperative Nausea ◽  
Pediatric Patients ◽  
Pediatric Population ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting ◽  
Antiemetic Drugs ◽  
Pacu Stay

OBJECTIVE Postoperative nausea and vomiting (PONV) is an extremely common side effect of general anesthesia that is difficult to manage. We tested a hypothesis that an aggressive prophylactic intervention with additional antiemetic drugs will reduce the incidence of PONV in a high-risk pediatric population undergoing adenotonsillectomy. METHODS In this retrospective study, pediatric patients undergoing adenotonsillectomy were screened for their risk factors for PONV. Patients who had 3 or more risk factors were identified as high risk and received either scopolamine patch preoperatively (for patients over 40 kg body weight) or diphenhydramine immediately postextubation in addition to ondansetron and dexamethasone, which are given routinely. Incidences of PONV within the first 60 minutes of a postanesthesia care unit (PACU) stay were collected and analyzed. RESULTS Overall postoperative vomiting rates during the first hour of a PACU stay were 4.3% for the group that was treated with dexamethasone and ondansetron only and 3.9% for the group that was treated with additional antiemetic drugs. Aggressive prophylactic management of PONV did reduce the rate of nausea and vomiting in a group of high-risk patients (p < 0.0001). The postoperative antiemetic drug usage was also decreased during the first 60 minutes of a PACU stay. However, the approach did not reduce the overall rate of PONV for the entire study population (p = 0.1612 for nausea and p = 0.0678 for vomiting). CONCLUSION Aggressive intraoperative management of PONV with additional antiemetic drugs are beneficial in high-risk pediatric population. Intraoperative diphenhydramine usage decreased the rate of PONV. However, preoperative scopolamine patch prevention did not improve PONV, which may be related to the drug's longer onset of action. Our result suggests that current clinical practice is undertreating PONV in pediatric patients receiving general anesthesia.

Echocardiography in Saanen-goats: Normal findings, reference intervals in awake goats, and the effect of general anesthesia

2011 ◽  
Vol 153 (12) ◽  
pp. 553-564 ◽  
Author(s):  
K. Steininger ◽  
A.-S. J. Berli ◽  
R. Jud ◽  
C. C. Schwarzwald
Keyword(s):  
General Anesthesia ◽  
Reference Intervals

Graduate Student Award, 1979: Consequences of Hearing During General Anesthesia

1980 ◽  
Author(s):  
Henry L. Bennett ◽  
Jeffrey A. Giannini ◽  
Mark D. Kline
Keyword(s):  
General Anesthesia ◽  
Graduate Student ◽  
Student Award

The Effects On Pilot Performance of Antiemetic Drugs Administered Singly And In Combination

1987 ◽  
Author(s):  
Henry L. Taylor ◽  
Fred C. Hyman ◽  
Martha H. Weller ◽  
Robert J. Nagel ◽  
Bruce C. Richardson ◽  
...  
Keyword(s):  
Pilot Performance ◽  
Antiemetic Drugs

The Use of General Anesthesia in the Office Surgery Facility

1983 ◽  
Vol 10 (2) ◽  
pp. 289-294
Author(s):  
H. William Porterfield ◽  
Lewis T. Franklin
Keyword(s):  
General Anesthesia
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