For people with intestinal helminths, what is the effect of anthelmintic drugs?

2020 ◽  
Author(s):  
Chaturaka Rodrigo
Keyword(s):  
Intestinal Helminths ◽  
Anthelmintic Drugs

scholarly journals Synthesis and Anthelmintic Activity of New Thiosemicarbazide Derivatives—A Preliminary Study

Molecules ◽  
2020 ◽  
Vol 25 (12) ◽  
pp. 2770 ◽  
Author(s):  
Katarzyna Dziduch ◽  
Przemysław Kołodziej ◽  
Agata Paneth ◽  
Anna Bogucka-Kocka ◽  
Monika Wujec
Keyword(s):  
Public Health ◽  
Anthelmintic Activity ◽  
Parasitic Infections ◽  
Intestinal Helminths ◽  
Preliminary Results ◽  
Preliminary Study ◽  
Thiosemicarbazide Derivatives ◽  
Anthelmintic Drugs

Parasitic infections caused by different species of intestinal helminths still poses a threat to public health. There is a need to search for new, effective anthelmintic drugs. A series of novel thiosemicarbazides were synthesized and evaluated for their in vitro anthelmintic activity. The preliminary results showed that the most of synthesized compounds were very active. 4-Phenyl-1-[(1-methyl-4-nitroimidazol-2-yl)carbonyl]thiosemicarbazide and 4-(3-chlorophenyl)-1-[(1-methyl-4-nitroimidazol-2-yl)carbonyl]thiosemicarbazide showed a 100% mortality of nematodes and a high anthelmintic activity in both tested concentrations.

Natural infection by intestinal cestodes: variability and effect on growth in Greater Snow Goose goslings (Chen caerulescens atlantica)

2002 ◽  
Vol 80 (6) ◽  
pp. 1077-1083 ◽  
Author(s):  
Mohamed Righi ◽  
Gilles Gauthier
Keyword(s):  
Intestinal Parasites ◽  
Natural Infection ◽  
Intestinal Helminths ◽  
Snow Goose ◽  
Chen Caerulescens ◽  
Greater Snow Goose ◽  
Chen Caerulescens Atlantica ◽  
And Control ◽  
Host Behaviour ◽  
Anthelmintic Drugs

We determined the species of intestinal helminths in Greater Snow Goose (Chen caerulescens atlantica) goslings and examined annual variability in infection levels over a 5-year period on Bylot Island, Nunavut. The intestines of 112 wild goslings collected when near fledging were examined. We also evaluated the effect of intestinal parasites on growth and behaviour of captive goslings in a controlled experiment. In 2000, one group (n = 11) was treated with anthelmintic drugs (Piperazine 52 for nematodes and Droncit® for cestodes) and the other (n = 14) was used as a control. Four hymenolepidid cestodes were identified: Drepanidotaenia lanceolata, Hymenolepis barrowensis, Microsom acanthus setigera, and Retinometra longivaginata. No nematodes were detected. Prevalence of intestinal cestodes in wild goslings was 100% but their abundance varied among years (from 28.9 ± 2.7 to 175.2 ± 49.7 (mean ± SE) cestodes per host) and individuals. Captive goslings treated with anthelmintic drugs were free of parasites, whereas all control goslings were parasitized when sacrificed at 36 d, although cestode abundance in the latter group was much lower (4.2 ± 0.7) than in wild goslings. There was no difference in growth rates between treated and control captive goslings until they were 36 d of age. However, treated goslings spent more time feeding than control ones, which suggests an effect of cestodes on host behaviour.

A study on the intestinal helminths of the patients in a leprosarium in Korea

1983 ◽  
Vol 21 (1) ◽  
pp. 102 ◽  
Author(s):  
Sung Tae Hong ◽  
Sung Jong Hong ◽  
Soon Hyung Lee ◽  
Ik Sang Kim ◽  
Jung Sik Shin
Keyword(s):  
Intestinal Helminths

Gastro-intestinal helminths detected by fecal examination in stray dogs in the Konya province

2014 ◽  
Vol 30 (3) ◽  
pp. 162-162 ◽  
Author(s):  
Nermin Isik ◽  
Özlem Derinbay Ekici ◽  
Serkan İrfan Köse
Keyword(s):  
Intestinal Helminths ◽  
Fecal Examination ◽  
Stray Dogs

scholarly journals Comorbidity of Geo-Helminthes among Malaria Outpatients of the Health Facilities in Ethiopia: Systematic Review and Meta-Analysis

2021 ◽  
Vol 18 (3) ◽  
pp. 862
Author(s):  
Minyahil Tadesse Boltena ◽  
Ziad El-Khatib ◽  
Abraham Sahlemichael Kebede ◽  
Benedict Oppong Asamoah ◽  
Andualem Tadesse Boltena ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Protein Energy Malnutrition ◽  
Random Effect ◽  
Plasmodium Species ◽  
Intestinal Helminth ◽  
Parasitic Infections ◽  
Intestinal Helminths ◽  
Soil Transmitted Helminths ◽  
Pooled Prevalence

Background: Coinfection of malaria and intestinal helminths affects one third of the global population, largely among communities with severe poverty. The spread of these parasitic infections overlays in several epidemiological locations and the host shows different outcomes. This systematic review and meta-analysis determine the pooled prevalence of malaria and intestinal helminthiases coinfections among malaria suspected patients in Ethiopia. Methods: Primary studies published in English language were retrieved using appropriate search terms on Google Scholar, PubMed/MEDLINE, CINHAL, Scopus, and Embase. The Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instrument (JBI-MAStARI) was used for critical appraisal of studies. A pooled statistical meta-analysis was conducted using STATA Version 14.0 software. The heterogeneity and publication bias were assessed using the I2 statistics and Egger’s test, respectively. Duval and Tweedie’s nonparametric trim and fill analysis using the random-effect analysis. The Random effects model was used to estimate the summary prevalence of comorbidity of malaria and soil transmitted helminthiases and the corresponding 95% confidence intervals (CI). The review protocol has registered in PROSPERO number CRD42019144803. Results: We identified ten studies (n = 6633 participants) in this study. The overall pooled result showed 13% of the ambulatory patients infected by malaria and intestinal helminths concurrently in Ethiopia. The pooled prevalence of Plasmodium falciparum and Plasmodium vivax, and mixed infections were 12, 30, and 6%, respectively. The most common intestinal helminth parasites detected were Hookworm, Ascaris lumbricoides, and Tirchuris trichiura. Conclusions: The comorbidity of malaria and intestinal helminths causes lower hemoglobin level leading to maternal anemia, preterm delivery, and still birth in pregnant women and lactating mother. School-aged children and neonates coinfected by plasmodium species and soil transmitted helminths develop cognitive impairment, protein energy malnutrition, low birth weight, small for gestational age, and gross motor delay. The Ministry of Health of Ethiopia and its international partners working on malaria elimination programs should give more emphasis to the effect of the interface of malaria and soil transmitted helminths, which calls for an integrated disease control and prevention.

Efficacy of Ivermectin in a Patient Population Concomitantly Infected with Intestinal Helminths and Ectoparasites

2011 ◽  
Vol 54 (07) ◽  
pp. 416-421
Author(s):  
Jörg Heukelbach ◽  
Thomas Wilcke ◽  
Benedikt Winter ◽  
Fabíola Oliveira ◽  
Rômulo Moura ◽  
...  
Keyword(s):  
Patient Population ◽  
Intestinal Helminths
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