What is the accuracy of scanning laser polarimetry (GDx) for diagnosing glaucoma?

2020 ◽  
Author(s):  
Jane Burch ◽  
Asaf Achiron
Keyword(s):  
Scanning Laser ◽  
Scanning Laser Polarimetry ◽  
Laser Polarimetry

scholarly journals Retinal nerve fibre layer thickness measurements in childhood glaucoma: the role of scanning laser polarimetry and optical coherence tomography

2021 ◽  
Author(s):  
Mael Lever ◽  
Christian Halfwassen ◽  
Jan Darius Unterlauft ◽  
Nikolaos E. Bechrakis ◽  
Anke Manthey ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Nerve Fibre ◽  
Retinal Nerve Fibre Layer ◽  
Scanning Laser ◽  
Optical Coherence ◽  
Scanning Laser Polarimetry ◽  
Laser Polarimetry ◽  
Nerve Fibre Layer ◽  
Thickness Measurements ◽  
Inferior Quadrant

Abstract Purpose A central diagnostic tool in adult glaucoma is the peripapillary retinal nerve fibre layer (pRNFL) thickness. It can be assessed by scanning laser polarimetry (SLP) or optical coherence tomography (OCT). However, studies investigating the relevance of pRNFL measurements in children are rare. This study aims to compare the glaucoma diagnosing ability of SLP and OCT pRNFL thickness measurements in a paediatric population. Methods This retrospective study included 105 children (glaucoma: 22 (21.0%); healthy glaucoma suspects: 83 (79.0%)) aged 4–18 years, examined with SLP (GDxPro/ECC, Carl Zeiss Meditec) and spectral-domain OCT (SPECTRALIS®, Heidelberg Engineering). The thickness of pRNFL sectors was compared between diseased and healthy participants. Areas under the receiver-operating characteristic curves (AUC) and logistic regression results were used to compare the glaucoma discriminative capacity between SLP and OCT measurements. Results Using OCT, pRNFL thickness was decreased in the superior, nasal, and inferior quadrants of glaucoma patients compared to healthy controls (P < 0.001, each). With SLP, such a difference was only observed in the inferior quadrant (P = 0.011). A correlation between glaucoma diagnosis and OCT-measured pRNFL thickness was found in all quadrants (P < 0.001) other than the temporal. With SLP, a correlation was found for the total average thickness (P = 0.037) and inferior quadrant (P = 0.0019). Finally, the AUCs of OCT measurements were markedly higher than those of SLP (e.g., inferior quadrant: OCT 0.83, SLP 0.68). Conclusion pRNFL thickness measurements using both OCT and SLP, correlate notably with the presence of glaucoma. In general, the diagnostic performance of pRNFL thickness measurements seems higher for OCT than for SLP. Thus, pRNFL thickness measurements could provide important information, complementing conventional clinical and functional parameters in the diagnostic process of paediatric glaucoma.

Predicting Visual Field Loss in Ocular Hypertensive Patients Using Wavelet-Fourier Analysis of GDx Scanning Laser Polarimetry

2007 ◽  
Vol 84 (5) ◽  
pp. E380-E387 ◽  
Author(s):  
EDWARD A. ESSOCK ◽  
PINAKIN GUNVANT ◽  
YUFENG ZHENG ◽  
DAVID F. GARWAY-HEATH ◽  
AACHAL KOTECHA ◽  
...  
Keyword(s):  
Visual Field ◽  
Fourier Analysis ◽  
Visual Field Loss ◽  
Scanning Laser ◽  
Scanning Laser Polarimetry ◽  
Hypertensive Patients ◽  
Laser Polarimetry

Vitreous opacities affect scanning laser polarimetry measurements

2001 ◽  
Vol 131 (4) ◽  
pp. 511-513 ◽  
Author(s):  
Mauricio E Pons ◽  
Robert F Rothman ◽  
Rabia Gurses Ozden ◽  
Jeffrey M Liebmann ◽  
Robert Ritch
Keyword(s):  
Scanning Laser ◽  
Scanning Laser Polarimetry ◽  
Laser Polarimetry ◽  
Vitreous Opacities
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