The effect of the size of fluorescent dextran on its endocytic pathway

2015 ◽  
Vol 39 (5) ◽  
pp. 531-539 ◽  
Author(s):  
Lei Li ◽  
Tao Wan ◽  
Min Wan ◽  
Bei Liu ◽  
Ran Cheng ◽  
...  
Keyword(s):  
Endocytic Pathway ◽  
Fluorescent Dextran

Basic Biology of Trypanosoma Cruzi

2020 ◽  
Vol 26 ◽  
Author(s):  
Aline Araujo Zuma ◽  
Emile dos Santos Barrias ◽  
Wanderley de Souza
Keyword(s):  
Trypanosoma Cruzi ◽  
Trypanosoma Brucei ◽  
Cell Biology ◽  
Structural Organization ◽  
Developmental Stages ◽  
Endocytic Pathway ◽  
Host Cells ◽  
Cellular Organization ◽  
Basic Biology ◽  
Comparative Information

Abstract:: The present review addresses basic aspects of the biology of the pathogenic protozoa Trypanosoma cruzi and some comparative information with Trypanosoma brucei. Like eukaryotic cells, their cellular organization is similar to that of mammalian hosts. However, these parasites present structural particularities. That is why the following topics are emphasized in this paper: developmental stages of the life cycle in the vertebrate and invertebrate hosts; the cytoskeleton of the protozoa, especially the sub-pellicular microtubules; the flagellum and its attachment to the protozoan body through specialized junctions; the kinetoplast-mitochondrion complex, including its structural organization and DNA replication; the glycosome and its role in the metabolism of the cell; the acidocalcisome, describing its morphology, biochemistry, and functional role; the cytostome and the endocytic pathway; the organization of the endoplasmic reticulum and Golgi complex; the nucleus, describing its structural organization during interphase and division; and the process of interaction of the parasite with host cells. The unique characteristics of these structures also make them interesting chemotherapeutic targets. Therefore, further understanding of cell biology aspects contributes to the development of drugs for chemotherapy.

scholarly journals Phosphatidylinositol 3,4-bisphosphate synthesis and turnover are spatially segregated in the endocytic pathway

2020 ◽  
Vol 295 (4) ◽  
pp. 1091-1104
Author(s):  
Haibin Wang ◽  
Dinah Loerke ◽  
Caroline Bruns ◽  
Rainer Müller ◽  
Philipp-Alexander Koch ◽  
...  
Keyword(s):  
Endocytic Pathway

scholarly journals Characterization of Two Protein Disulfide Isomerases from the Endocytic Pathway of Bloodstream Forms of Trypanosoma brucei

2005 ◽  
Vol 280 (11) ◽  
pp. 10410-10418 ◽  
Author(s):  
Joyce Rubotham ◽  
Katherine Woods ◽  
Jose A. Garcia-Salcedo ◽  
Etienne Pays ◽  
Derek P. Nolan
Keyword(s):  
Trypanosoma Brucei ◽  
Endocytic Pathway ◽  
Protein Disulfide Isomerases ◽  
Disulfide Isomerases ◽  
Protein Disulfide

Visualizing Lysosomal Membrane Permeabilization by Fluorescent Dextran Release: Figure 1.

2015 ◽  
Vol 2015 (10) ◽  
pp. pdb.prot086173 ◽  
Author(s):  
Anne-Marie Ellegaard ◽  
Marja Jäättelä ◽  
Jesper Nylandsted
Keyword(s):  
Membrane Permeabilization ◽  
Lysosomal Membrane ◽  
Lysosomal Membrane Permeabilization ◽  
Fluorescent Dextran
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