scholarly journals Taming the Reactivity of Monoterpene Synthases To Guide Regioselective Product Hydroxylation

ChemBioChem ◽  
2020 ◽  
Vol 21 (7) ◽  
pp. 985-990 ◽  
Author(s):  
Nicole G. H. Leferink ◽  
Kara E. Ranaghan ◽  
Jaime Battye ◽  
Linus O. Johannissen ◽  
Sam Hay ◽  
...  
Keyword(s):  
Monoterpene Synthases

Computational Simulations for Cyclizations Catalyzed by Plant Monoterpene Synthases

2020 ◽  
pp. 247-258
Author(s):  
Waldeyr Mendes Cordeiro da Silva ◽  
Daniela P. de Andrade ◽  
Jakob L. Andersen ◽  
Maria Emília M. T. Walter ◽  
Marcelo Brigido ◽  
...  
Keyword(s):  
Computational Simulations ◽  
Monoterpene Synthases

scholarly journals Product Variability of the ‘Cineole Cassette’ Monoterpene Synthases of Related Nicotiana Species

2011 ◽  
Vol 4 (6) ◽  
pp. 965-984 ◽  
Author(s):  
Anke Fähnrich ◽  
Katrin Krause ◽  
Birgit Piechulla
Keyword(s):  
Nicotiana Species ◽  
Monoterpene Synthases

Monoterpene Synthases of Loblolly Pine (Pinus taeda) Produce Pinene Isomers and Enantiomers

1999 ◽  
Vol 372 (1) ◽  
pp. 197-204 ◽  
Author(s):  
Michael A. Phillips ◽  
Thomas J. Savage ◽  
Rodney Croteau
Keyword(s):  
Pinus Taeda ◽  
Loblolly Pine ◽  
Monoterpene Synthases

Monoterpene synthases from Gymnosperms and angiosperms: Stereospecificity and inactivation by cysteinyl- and arginyl-directed modifying reagents

1995 ◽  
Vol 320 (2) ◽  
pp. 257-265 ◽  
Author(s):  
Thomas J. Savage ◽  
Hiroko Ichii ◽  
Steven D. Hume ◽  
Dawn B. Litte ◽  
Rodyney Croteau
Keyword(s):  
Monoterpene Synthases

Domain swapping of Citrus limon monoterpene synthases: impact on enzymatic activity and product specificity

2003 ◽  
Vol 411 (2) ◽  
pp. 196-203 ◽  
Author(s):  
Mazen K El Tamer ◽  
Joost Lücker ◽  
Dirk Bosch ◽  
Harrie A Verhoeven ◽  
Francel W.A Verstappen ◽  
...  
Keyword(s):  
Enzymatic Activity ◽  
Domain Swapping ◽  
Citrus Limon ◽  
Product Specificity ◽  
Monoterpene Synthases

scholarly journals Functional Expression and Characterization of Trichome-Specific (-)-Limonene Synthase and (+)-α-Pinene Synthase from Cannabis sativa

2007 ◽  
Vol 2 (3) ◽  
pp. 1934578X0700200 ◽  
Author(s):  
Nils Günnewich ◽  
Jonathan E. Page ◽  
Tobias G. Köllner ◽  
Jörg Degenhardt ◽  
Toni M. Kutchan
Keyword(s):  
Phylogenetic Analysis ◽  
Natural Products ◽  
Cannabis Sativa ◽  
Functional Expression ◽  
Temperature Optimum ◽  
Ph Optimum ◽  
Limonene Synthase ◽  
Monoterpene Synthases

Two recombinant, stereospecific monoterpene synthases, a (-)-limonene synthase (CsTPS1) and a (+)-α-pinene synthase (CsTPS2), encoded by Cannabis sativa L. cv. ‘Skunk’ trichome mRNA, have been isolated and characterized. Recombinant CsTPS1 showed a Km value of 6.8 μM, a Vmax of 1.1 × 10−4 μmol/min and Vmax/Km of 0.016; the pH optimum was determined at pH 6.5, and a temperature optimum at 40°C. Recombinant CsTPS2 showed a Km value of 10.5 μM, a Vmax of 2.2 × 10−4 μmol/min and Vmax/Km of 0.021; the pH optimum was determined at pH 7.0, and a temperature optimum at 30°C. Phylogenetic analysis showed that both CsTPSs group within the angiosperms and belong to the Tpsb subgroup of monoterpene synthases. The enzymatic products (-)-limonene and (+)-α-pinene were detected as natural products in C. sativa trichomes.

scholarly journals Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase

ACS Catalysis ◽  
2017 ◽  
Vol 7 (9) ◽  
pp. 6268-6282 ◽  
Author(s):  
Vijaykumar Karuppiah ◽  
Kara E. Ranaghan ◽  
Nicole G. H. Leferink ◽  
Linus O. Johannissen ◽  
Muralidharan Shanmugam ◽  
...  
Keyword(s):  
Structural Basis ◽  
Monoterpene Synthases ◽  
Linalool Synthase

scholarly journals Molecular determinants for carbocation cyclisation in bacterial monoterpene synthases

ChemBioChem ◽  
2022 ◽  
Author(s):  
Nicole G. H. Leferink ◽  
Andrés M. Escorcia ◽  
Bodi R. Ouwersloot ◽  
Linus O. Johanissen ◽  
Sam Hay ◽  
...  
Keyword(s):  
Molecular Determinants ◽  
Monoterpene Synthases

scholarly journals Monoterpene Synthases from Common Sage (Salvia officinalis)

1998 ◽  
Vol 273 (24) ◽  
pp. 14891-14899 ◽  
Author(s):  
Mitchell L. Wise ◽  
Thomas J. Savage ◽  
Eva Katahira ◽  
Rodney Croteau
Keyword(s):  
Salvia Officinalis ◽  
Monoterpene Synthases
Sign in / Sign up

Export Citation Format

Share Document