Molecular Design of an Environmentally Sensitive Fluorescent Nucleoside, 3-Deaza-2′-Deoxyadenosine Derivative: Distinguishing Thymine by Probing the DNA Minor Groove

ChemBioChem ◽  
2014 ◽  
Vol 15 (11) ◽  
pp. 1638-1644 ◽  
Author(s):  
Azusa Suzuki ◽  
Takumi Yanaba ◽  
Isao Saito ◽  
Yoshio Saito
Keyword(s):  
Molecular Design ◽  
Minor Groove ◽  
Dna Minor Groove ◽  
Environmentally Sensitive ◽  
Fluorescent Nucleoside

Synthesis of 8-aza-3,7-dideaza-2′-deoxyadenosines possessing a new adenosine skeleton as an environmentally sensitive fluorescent nucleoside for monitoring the DNA minor groove

2015 ◽  
Vol 13 (27) ◽  
pp. 7459-7468 ◽  
Author(s):  
Azusa Suzuki ◽  
Mio Saito ◽  
Ryuzi Katoh ◽  
Yoshio Saito
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Minor Groove ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide ◽  
Dna Minor Groove ◽  
Snp Typing ◽  
Environmentally Sensitive ◽  
Fluorescent Nucleoside

Fluorescent ODN probes containing3n7zA(2) acted as effective reporter probes for homogeneous single nucleotide polymorphism (SNP) typing.

The fluorescently responsive 3-(naphthalen-1-ylethynyl)-3-deaza-2′-deoxyguanosine discriminates cytidine via the DNA minor groove

2017 ◽  
Vol 15 (37) ◽  
pp. 7853-7859 ◽  
Author(s):  
Azusa Suzuki ◽  
Masaki Yanagi ◽  
Takuya Takeda ◽  
Robert H. E. Hudson ◽  
Yoshio Saito
Keyword(s):  
Minor Groove ◽  
Emission Wavelength ◽  
Dna Minor Groove ◽  
Target Dna ◽  
Dna Strands ◽  
Fluorescent Nucleoside

A newly synthesized fluorescent nucleoside 3nzG discriminates cytidine in target DNA strands by a distinct change in its emission wavelength.

scholarly journals Cellular pharmacology of novel C8-linked anthramycin-based sequence-selective DNA minor groove cross-linking agents

1994 ◽  
Vol 70 (1) ◽  
pp. 48-53 ◽  
Author(s):  
M Smellie ◽  
LR Kelland ◽  
DE Thurston ◽  
RL Souhami ◽  
JA Hartley
Keyword(s):  
Minor Groove ◽  
Cross Linking ◽  
Dna Minor Groove ◽  
Cellular Pharmacology

Molecular dynamics simulations and binding free energy analysis of DNA minor groove complexes of curcumin

2011 ◽  
Vol 17 (11) ◽  
pp. 2805-2816 ◽  
Author(s):  
Mathew Varghese Koonammackal ◽  
Unnikrishnan Viswambharan Nair Nellipparambil ◽  
Chellappanpillai Sudarsanakumar
Keyword(s):  
Molecular Dynamics ◽  
Free Energy ◽  
Molecular Dynamics Simulations ◽  
Energy Analysis ◽  
Binding Free Energy ◽  
Minor Groove ◽  
Dna Minor Groove ◽  
Dynamics Simulations ◽  
Free Energy Analysis

Influence of GC and AT Specific DNA Minor Groove Binding Drugs on Intermolecular Triplex Formation in the Human c-Ki-ras Promoter†

Biochemistry ◽  
1996 ◽  
Vol 35 (4) ◽  
pp. 1106-1114 ◽  
Author(s):  
Nadarajah Vigneswaran ◽  
Charles A. Mayfield ◽  
Brad Rodu ◽  
Roger James ◽  
H.-G. Kim ◽  
...  
Keyword(s):  
Minor Groove ◽  
Minor Groove Binding ◽  
Groove Binding ◽  
Dna Minor Groove ◽  
Triplex Formation
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