Functional Immobilization of the Small GTPase Rab6A on DNA–Gold Nanoparticles by Using a Site-Specifically Attached Poly(ethylene glycol) Linker and Thiol Place-Exchange Reaction

ChemBioChem ◽  
2007 ◽  
Vol 8 (1) ◽  
pp. 32-36 ◽  
Author(s):  
Christian F. W. Becker ◽  
Yoann Marsac ◽  
Pompi Hazarika ◽  
Jens Moser ◽  
Roger S. Goody ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Ethylene Glycol ◽  
Exchange Reaction ◽  
Small Gtpase ◽  
Poly Ethylene Glycol ◽  
Place Exchange ◽  
Poly Ethylene ◽  
A Site

Transdermal delivery of poly(ethylene glycol)-co-oleylamine modified gold nanoparticles: Effect of size and shape

2019 ◽  
Vol 224 ◽  
pp. 22-28 ◽  
Author(s):  
Pa Fan Hsiao ◽  
Hsieh-Chih Tsai ◽  
Sydney Peng ◽  
Adhimoorthy Prasannan ◽  
Ting-Cheng Tang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Ethylene Glycol ◽  
Transdermal Delivery ◽  
Poly Ethylene Glycol ◽  
Size And Shape ◽  
Poly Ethylene

scholarly journals Enhanced dispersion stability of gold nanoparticles by the physisorption of cyclic poly(ethylene glycol)

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Yubo Wang ◽  
Jose Enrico Q. Quinsaat ◽  
Tomoko Ono ◽  
Masatoshi Maeki ◽  
Manabu Tokeshi ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Ethylene Glycol ◽  
Dispersion Stability ◽  
Chemical Inhomogeneity ◽  
Poly Ethylene Glycol ◽  
Alternative Approach ◽  
Ft Ir ◽  
Poly Ethylene ◽  
Tumor Accumulation ◽  
Key Techniques

AbstractNano-sized metal particles are attracting much interest in industrial and biomedical applications due to the recent progress and development of nanotechnology, and the surface-modifications by appropriate polymers are key techniques to stably express their characteristics. Herein, we applied cyclic poly(ethylene glycol) (c-PEG), having no chemical inhomogeneity, to provide a polymer topology-dependent stabilization for the surface-modification of gold nanoparticles (AuNPs) through physisorption. By simply mixing c-PEG, but not linear counterparts, enables AuNPs to maintain dispersibility through freezing, lyophilization, or heating. Surprisingly, c-PEG endowed AuNPs with even better dispersion stability than thiolated PEG (HS–PEG–OMe). The stronger affinity of c-PEG was confirmed by DLS, ζ-potential, and FT-IR. Furthermore, the c-PEG system exhibited prolonged blood circulation and enhanced tumor accumulation in mice. Our data suggests that c-PEG induces physisorption on AuNPs, supplying sufficient stability toward bio-medical applications, and would be an alternative approach to the gold–sulfur chemisorption.

Enhanced target recognition of nanoparticles by cocktail PEGylation with chains of varying lengths

2016 ◽  
Vol 52 (7) ◽  
pp. 1517-1519 ◽  
Author(s):  
Takehiko Ishii ◽  
Kanjiro Miyata ◽  
Yasutaka Anraku ◽  
Mitsuru Naito ◽  
Yu Yi ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Ethylene Glycol ◽  
Target Recognition ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Monodispersed gold nanoparticles (AuNPs) were simultaneously decorated with lactosylated and non-modified shorter poly(ethylene glycol)s (PEGs) to enhance their target recognition.

The effect of ligand composition on the in vivo fate of multidentate poly(ethylene glycol) modified gold nanoparticles

Biomaterials ◽  
2013 ◽  
Vol 34 (33) ◽  
pp. 8370-8381 ◽  
Author(s):  
Xiangsheng Liu ◽  
Nan Huang ◽  
Haibo Wang ◽  
Huan Li ◽  
Qiao Jin ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene
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