NMR Backbone Assignment of a Protein Kinase Catalytic Domain by a Combination of Several Approaches: Application to the Catalytic Subunit of cAMP-Dependent Protein Kinase

Thomas Langer; Martin Vogtherr; Bettina Elshorst; Marco Betz; Ulrich Schieborr; Krishna Saxena; Harald Schwalbe

doi:10.1002/cbic.200400129

NMR Backbone Assignment of a Protein Kinase Catalytic Domain by a Combination of Several Approaches: Application to the Catalytic Subunit of cAMP-Dependent Protein Kinase

ChemBioChem ◽

10.1002/cbic.200400129 ◽

2004 ◽

Vol 5 (11) ◽

pp. 1508-1516 ◽

Cited By ~ 47

Author(s):

Thomas Langer ◽

Martin Vogtherr ◽

Bettina Elshorst ◽

Marco Betz ◽

Ulrich Schieborr ◽

...

Keyword(s):

Protein Kinase ◽

Catalytic Domain ◽

Backbone Assignment ◽

Catalytic Subunit ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Kinase Catalytic Domain ◽

Dependent Protein

Download Full-text

Rapid and reversible translocation of the catalytic subunit of cAMP-dependent protein kinase type II from the Golgi complex to the nucleus.

The EMBO Journal ◽

10.1002/j.1460-2075.1985.tb04006.x ◽

1985 ◽

Vol 4 (11) ◽

pp. 2801-2806 ◽

Cited By ~ 217

Author(s):

E.A. Nigg ◽

H. Hilz ◽

H.M. Eppenberger ◽

F. Dutly

Keyword(s):

Protein Kinase ◽

Golgi Complex ◽

Catalytic Subunit ◽

Type Ii ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

Download Full-text

Glutamic acid 203 of the cAMP-dependent protein kinase catalytic subunit participates in the inhibition by two isoforms of the protein kinase inhibitor.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)42170-3 ◽

1994 ◽

Vol 269 (3) ◽

pp. 2316-2323

Author(s):

E.J. Baude ◽

S.S. Dignam ◽

S.R. Olsen ◽

E.M. Reimann ◽

M.D. Uhler

Keyword(s):

Protein Kinase ◽

Glutamic Acid ◽

Kinase Inhibitor ◽

Protein Kinase Inhibitor ◽

Catalytic Subunit ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

Download Full-text

Effect of the thermostable protein kinase inhibitor on intracellular localization of the catalytic subunit of cAMP-dependent protein kinase.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)41857-1 ◽

1992 ◽

Vol 267 (24) ◽

pp. 16824-16828 ◽

Cited By ~ 2

Author(s):

D.A. Fantozzi ◽

S.S. Taylor ◽

P.W. Howard ◽

R.A. Maurer ◽

J.R. Feramisco ◽

...

Keyword(s):

Protein Kinase ◽

Kinase Inhibitor ◽

Intracellular Localization ◽

Protein Kinase Inhibitor ◽

Catalytic Subunit ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein ◽

Thermostable Protein

Download Full-text

Cloning, characterization, and expression of the gene for the catalytic subunit of cAMP-dependent protein kinase in Caenorhabditis elegans. Identification of highly conserved and unique isoforms generated by alternative splicing.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)39234-8 ◽

1990 ◽

Vol 265 (12) ◽

pp. 6896-6907

Author(s):

R E Gross ◽

S Bagchi ◽

X Lu ◽

C S Rubin

Keyword(s):

Alternative Splicing ◽

Caenorhabditis Elegans ◽

Protein Kinase ◽

Catalytic Subunit ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

Download Full-text

Mg X ATP2-dependent interaction of the inhibitor protein of the cAMP-dependent protein kinase with the catalytic subunit.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)32719-4 ◽

1983 ◽

Vol 258 (6) ◽

pp. 3682-3692 ◽

Cited By ~ 13

Author(s):

S Whitehouse ◽

D A Walsh

Keyword(s):

Protein Kinase ◽

Catalytic Subunit ◽

Inhibitor Protein ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein ◽

Dependent Interaction

Download Full-text

The in vitro phosphorylation of chromatin by the catalytic subunit of cAMP-dependent protein kinase.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(20)65104-3 ◽

1982 ◽

Vol 257 (11) ◽

pp. 6056-6063 ◽

Cited By ~ 1

Author(s):

S S Taylor

Keyword(s):

Protein Kinase ◽

Catalytic Subunit ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

Download Full-text

Influence of Myristoylation, Phosphorylation, and Deamidation on the Structural Behavior of the N-Terminus of the Catalytic Subunit of CAMP-Dependent Protein Kinase†

Biochemistry ◽

10.1021/bi0021277 ◽

2001 ◽

Vol 40 (1) ◽

pp. 225-231 ◽

Cited By ~ 30

Author(s):

Andreas Tholey ◽

Rüdiger Pipkorn ◽

Dirk Bossemeyer ◽

Volker Kinzel ◽

Jennifer Reed

Keyword(s):

Protein Kinase ◽

Catalytic Subunit ◽

Structural Behavior ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

N Terminus ◽

Dependent Protein

Download Full-text

AMY-1 Interacts with S-AKAP84 and AKAP95 in the Cytoplasm and the Nucleus, Respectively, and Inhibits cAMP-dependent Protein Kinase Activity by Preventing Binding of Its Catalytic Subunit to A-kinase-anchoring Protein (AKAP) Complex

Journal of Biological Chemistry ◽

10.1074/jbc.m206387200 ◽

2002 ◽

Vol 277 (52) ◽

pp. 50885-50892 ◽

Cited By ~ 26

Author(s):

Makoto Furusawa ◽

Takahiro Taira ◽

Sanae M. M. Iguchi-Ariga ◽

Hiroyoshi Ariga

Keyword(s):

Protein Kinase ◽

Kinase Activity ◽

Catalytic Subunit ◽

Protein Kinase Activity ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Anchoring Protein ◽

Dependent Protein

Download Full-text

Modulation of Regulatory and Catalytic Subunit Levels of cAMP-Dependent Protein Kinase A in Anterior Pituitary Cells in Response to Direct Activation of Protein Kinases A and C or after GnRH Stimulation

Neuroendocrinology ◽

10.1159/000127042 ◽

1995 ◽

Vol 62 (5) ◽

pp. 514-522 ◽

Cited By ~ 15

Author(s):

Ghislaine Garrel ◽

Richard Delahaye ◽

Brian A. Hemmings ◽

Raymond Counis

Keyword(s):

Protein Kinase ◽

Protein Kinase A ◽

Protein Kinases ◽

Anterior Pituitary ◽

Catalytic Subunit ◽

Pituitary Cells ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein ◽

Kinase A

Download Full-text

Mutagenesis of the regulatory subunit of yeast cAMP-dependent protein kinase. Isolation of site-directed mutants with altered binding affinity for catalytic subunit.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)76519-3 ◽

1988 ◽

Vol 263 (19) ◽

pp. 9149-9154

Author(s):

J Kuret ◽

K E Johnson ◽

C Nicolette ◽

M J Zoller

Keyword(s):

Protein Kinase ◽

Binding Affinity ◽

Catalytic Subunit ◽

Regulatory Subunit ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

Download Full-text