Effects of physical exercise training in DNA damage and repair activity in humans with different genetic polymorphisms ofhOGG1(Ser326Cys)

2015 ◽  
Vol 33 (8) ◽  
pp. 519-524 ◽  
Author(s):  
Jorge Pinto Soares ◽  
Ana Inês Silva ◽  
Amélia M. Silva ◽  
Vanessa Almeida ◽  
João Paulo Teixeira ◽  
...  
Keyword(s):  
Dna Damage ◽  
Exercise Training ◽  
Physical Exercise ◽  
Genetic Polymorphisms ◽  
Dna Damage And Repair ◽  
Physical Exercise Training ◽  
Repair Activity

scholarly journals Effects of combined physical exercise training on DNA damage and repair capacity: role of oxidative stress changes

AGE ◽  
2015 ◽  
Vol 37 (3) ◽  
Author(s):  
Jorge Pinto Soares ◽  
Amélia M. Silva ◽  
Maria Manuel Oliveira ◽  
Francisco Peixoto ◽  
Isabel Gaivão ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Dna Damage ◽  
Exercise Training ◽  
Physical Exercise ◽  
Repair Capacity ◽  
Dna Damage And Repair ◽  
Physical Exercise Training ◽  
Stress Changes

scholarly journals The Effects of Combined Physical Exercise on Serum Redox Biomarkers and Leukocyte DNA Damage of Obese Women

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Carla Nascimento ◽  
Milena Simões Peixoto ◽  
Luiz Fernando Fonte Boa ◽  
Caroline Coelho de Faria ◽  
Tulio Senna Fonseca Costa ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Dna Damage ◽  
Exercise Training ◽  
Physical Exercise ◽  
Body Fat ◽  
Physical Training ◽  
Fat Free Mass ◽  
Obese Women ◽  
Chromosomal Damage ◽  
Physical Exercise Training

Obesity is usually linked to oxidative stress, which can lead to damage to biomolecules. The combination of aerobic and strength exercises seems to induce health benefits in obese individuals, but little is known about the effects of combined physical exercise on redox homeostasis and DNA damage in this population. Thus, the aim of the current study was to determine the effects of 16 weeks of combined physical exercise on biomarkers of oxidative stress and DNA damage in obese women. 17 obese women underwent 16 weeks of a combined physical training program, 3 times per week. Anthropometric and biochemical parameters, serum superoxide dismutase (SOD) and glutathione peroxidase activity, plasma 8-isoprostane levels, and DNA and chromosomal damage were evaluated before and after physical training. Combined physical exercise training decreased body weight ( 83.2 ± 9.6 vs. 80.2 ± 9.6  kg), body mass index ( 33.8 ± 3.6 vs. 32.6 ± 3.7  kg·m-2), body fat ( 40.2 ± 2.6 vs. 39.0 ± 3.2 %), and waist circumference ( 99.3 ± 9.4 vs. 94.1 ± 8.8  cm), while the fat-free mass was augmented ( 59.9 ± 2.9 vs. 60.7 ± 3.1  kg). Moreover, blood glucose reduced ( 113.5 ± 29.6 vs. 107.3 ± 28.9  mg/dL) along with high-density lipoprotein ( 54.6 ± 18.1 vs. 59.0 ± 18.8  mg/dL), TSH ( 2.1 ± 1.1 vs. 2.6 ± 1.2  mIU/mL), and free T4 ( 0.9 ± 0.1 vs. 1.12 ± 0.2  ng/dL) increase after physical exercise training. Plasma 8-isoprostane levels ( 17.24 ± 7.9 vs. 29.11 ± 17.44  pg/mL) and DNA damage ( 34.16 ± 7.1 vs. 45.96 ± 5.8 % DNA in tail) were also higher after physical training. No changes were observed in chromosomal damage levels. These results suggest that 16 weeks of combined exercise training 3 times per week is effective in reducing body fat but also increases oxidative stress and DNA damage in obese women.

Enhancing Patient Motivation through Intelligibility in Cardiac Tele-rehabilitation

2019 ◽  
Vol 31 (2) ◽  
pp. 122-137
Author(s):  
Supraja Sankaran ◽  
Kris Luyten ◽  
Dominique Hansen ◽  
Paul Dendale ◽  
Karin Coninx
Keyword(s):  
Medication Adherence ◽  
Exercise Training ◽  
Physical Exercise ◽  
Health Outcomes ◽  
Cardiac Rehabilitation ◽  
Field Studies ◽  
Activity Levels ◽  
Patient Motivation ◽  
Physical Exercise Training ◽  
The Impact

Abstract Physical exercise training and medication compliance are primary components of cardiac rehabilitation. When rehabilitating independently at home, patients often fail to comply with their prescribed medication and find it challenging to interpret exercise targets or be aware of the expected efforts. Our work aims to assist cardiac patients in understanding their condition better, promoting medication adherence and motivating them to achieve their exercise targets in a tele-rehabilitation setting. We introduce a patient-centric intelligible visualization approach to present prescribed medication and exercise targets to patients. We assessed efficacy of intelligible visualizations on patients’ comprehension in two lab studies. We evaluated the impact on patient motivation and health outcomes in field studies. Patients were able to adhere to medication prescriptions, manage their physical exercises, monitor their progress and gained better self-awareness on how they achieved their rehabilitation targets. Patients confirmed that the intelligible visualizations motivated them to achieve their targets better. We observed an improvement in overall physical activity levels and health outcomes of patients. Research Highlights Presents challenges currently faced in cardiac tele-rehabilitation. Demonstrates how intelligibility was applied to two core aspects of cardiac rehabilitation- promoting medication adherence and physical exercise training. Lab., field and clinical studies to demonstrate efficacy of intelligible visualization, impact on patient motivation and resultant health outcomes. Reflection on how similar HCI approaches could be leveraged for technology-supported management of critical health conditions such as cardiac diseases.

Carnitine in muscle, serum, and urine of nonprofessional athletes: Effects of physical exercise, training, and L-carnitine administration

1991 ◽  
Vol 14 (7) ◽  
pp. 598-604 ◽  
Author(s):  
J. Arenas ◽  
J. R. Ricoy ◽  
A. R. Encinas ◽  
P. Pola ◽  
S. D'Iddio ◽  
...  
Keyword(s):  
Exercise Training ◽  
Physical Exercise ◽  
Physical Exercise Training ◽  
Serum And Urine

scholarly journals Benefits of Physical Exercise Training on Cognition and Quality of Life in Frail Older Adults

2012 ◽  
Vol 68 (3) ◽  
pp. 400-404 ◽  
Author(s):  
F. Langlois ◽  
T. T. M. Vu ◽  
K. Chasse ◽  
G. Dupuis ◽  
M.-J. Kergoat ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Older Adults ◽  
Exercise Training ◽  
Physical Exercise ◽  
Frail Older Adults ◽  
Physical Exercise Training
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