Localization of putative gonadotrophin releasing hormone receptor protein in the anterior pituitary

1984 ◽  
Vol 2 (4) ◽  
pp. 208-212 ◽  
Author(s):  
Joseph C. Zolman ◽  
Theodor J. Theodoropoulos
Keyword(s):  
Hormone Receptor ◽  
Anterior Pituitary ◽  
Receptor Protein ◽  
Releasing Hormone ◽  
Gonadotrophin Releasing Hormone

scholarly journals Tissue-specific molecular heterogeneity of human growth hormone-releasing hormone receptor protein

FEBS Letters ◽  
1996 ◽  
Vol 394 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Yuichi Fujinaka ◽  
Yutaka Yokogoshi ◽  
Chen-Yu Zhang ◽  
Toshihiro Okura ◽  
Kouki Kitagawa ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Hormone Receptor ◽  
Human Growth ◽  
Receptor Protein ◽  
Molecular Heterogeneity ◽  
Growth Hormone Releasing Hormone ◽  
Tissue Specific ◽  
Releasing Hormone

Infertility

2013 ◽  
pp. 551-566
Author(s):  
John Reynard ◽  
Simon Brewster ◽  
Suzanne Biers
Keyword(s):  
Luteinizing Hormone ◽  
Male Infertility ◽  
Anterior Pituitary ◽  
Treatment Options ◽  
Follicle Stimulating Hormone ◽  
Reproductive Physiology ◽  
Seminiferous Tubules ◽  
Luteinizing Hormone Releasing Hormone ◽  
Releasing Hormone ◽  
Gonadotrophin Releasing Hormone

Male reproductive physiology 552 Aetiology and evaluation of male infertility 554 Investigation of male infertility 556 Oligozoospermia and azoospermia 560 Varicocele 562 Treatment options for male infertility 564 The hypothalamus secretes luteinizing hormone-releasing hormone (LHRH), also known as gonadotrophin-releasing hormone (GnRH). This causes the pulsatile release of anterior pituitary gonadotrophins called follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which act on the testis. FSH stimulates the seminiferous tubules to secrete inhibin and produce sperm; LH acts on Leydig cells to produce testosterone (...

Effects of corticotropin-releasing hormone and its antagonist on the gene expression of gonadotrophin-releasing hormone (GnRH) and GnRH receptor in the hypothalamus and anterior pituitary gland of follicular phase ewes

2011 ◽  
Vol 23 (6) ◽  
pp. 780 ◽  
Author(s):  
Magdalena Ciechanowska ◽  
Magdalena Łapot ◽  
Tadeusz Malewski ◽  
Krystyna Mateusiak ◽  
Tomasz Misztal ◽  
...  
Keyword(s):  
Gene Expression ◽  
Pituitary Gland ◽  
Anterior Pituitary ◽  
Follicular Phase ◽  
Gnrh Receptor ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone ◽  
Gonadotrophin Releasing Hormone ◽  
Lh Secretion ◽  
Crh Receptors

There is no information in the literature regarding the effect of corticotropin-releasing hormone (CRH) on genes encoding gonadotrophin-releasing hormone (GnRH) and the GnRH receptor (GnRHR) in the hypothalamus or on GnRHR gene expression in the pituitary gland in vivo. Thus, the aim of the present study was to investigate, in follicular phase ewes, the effects of prolonged, intermittent infusion of small doses of CRH or its antagonist (α-helical CRH 9-41; CRH-A) into the third cerebral ventricle on GnRH mRNA and GnRHR mRNA levels in the hypothalamo–pituitary unit and on LH secretion. Stimulation or inhibition of CRH receptors significantly decreased or increased GnRH gene expression in the hypothalamus, respectively, and led to different responses in GnRHR gene expression in discrete hypothalamic areas. For example, CRH increased GnRHR gene expression in the preoptic area, but decreased it in the hypothalamus/stalk median eminence and in the anterior pituitary gland. In addition, CRH decreased LH secretion. Blockade of CRH receptors had the opposite effect on GnRHR gene expression. The results suggest that activation of CRH receptors in the hypothalamus of follicular phase ewes can modulate the biosynthesis and release of GnRH through complex changes in the expression of GnRH and GnRHR genes in the hypothalamo–anterior pituitary unit.

P-201. Gonadotrophin releasing hormone receptor mutations in hypogonadism

1999 ◽  
Vol 14 (Suppl_3) ◽  
pp. 241-242
Author(s):  
M.L. Kottler ◽  
S. Chauvin ◽  
P. Caron ◽  
N. Farid ◽  
S. Christin ◽  
...  
Keyword(s):  
Hormone Receptor ◽  
Releasing Hormone ◽  
Gonadotrophin Releasing Hormone
Sign in / Sign up

Export Citation Format

Share Document