Synthesis, Biological Activity and Action Mechanism Study of Novel Chalcone Derivatives Containing Malonate

2020 ◽  
Vol 17 (4) ◽  
Author(s):  
Tao Guo ◽  
Rongjiao Xia ◽  
Tingting Liu ◽  
Feng Peng ◽  
Xuemei Tang ◽  
...  
Keyword(s):  
Biological Activity ◽  
Mechanism Study ◽  
Action Mechanism ◽  
Chalcone Derivatives

scholarly journals Biological activity evaluation and action mechanism of chalcone derivatives containing thiophene sulfonate

RSC Advances ◽  
2019 ◽  
Vol 9 (43) ◽  
pp. 24942-24950 ◽  
Author(s):  
Tao Guo ◽  
Rongjiao Xia ◽  
Mei Chen ◽  
Jun He ◽  
Shijun Su ◽  
...  
Keyword(s):  
Biological Activity ◽  
Action Mechanism ◽  
Chalcone Derivatives ◽  
Activity Evaluation ◽  
Antiviral Activities

Synthesis, antibacterial, antiviral activities and action mechanism of chalcone derivatives containing thiophene sulfonate.

Action mechanism and biological activity of celangulin to Tetranychus cinnabarinus (Acari: Tetranychidae)

2004 ◽  
Vol 9 (0) ◽  
pp. 27
Author(s):  
WEI DING ◽  
ZHIMO ZHAO ◽  
WENJUN WU ◽  
HUIYING TAO ◽  
JINJUN WANG
Keyword(s):  
Biological Activity ◽  
Tetranychus Cinnabarinus ◽  
Action Mechanism

Antimicrobial evaluation and action mechanism of chalcone derivatives containing quinoxaline moiety

2019 ◽  
Vol 150 (7) ◽  
pp. 1325-1334 ◽  
Author(s):  
Rongjiao Xia ◽  
Tao Guo ◽  
Jun He ◽  
Mei Chen ◽  
Shijun Su ◽  
...  
Keyword(s):  
Action Mechanism ◽  
Chalcone Derivatives ◽  
Antimicrobial Evaluation

scholarly journals Synthesis and Biological Activity of Novel Chalcone Derivatives Containing 2-Substituted-1,3-thiazolidine Ring

2012 ◽  
Vol 32 (9) ◽  
pp. 1690
Author(s):  
Hong Dai ◽  
Wenke Miao ◽  
Jianbing Liu ◽  
Shanshan Wu ◽  
Xue Qin ◽  
...  
Keyword(s):  
Biological Activity ◽  
Chalcone Derivatives ◽  
Thiazolidine Ring

scholarly journals Biological activity screening of some hydrazone and chalcone derivatives

2021 ◽  
Vol 78 (2) ◽  
pp. 159-166
Author(s):  
Begüm Evranos Aksöz ◽  
Fatma Kaynak-Onurdag ◽  
Erkan Aksoz ◽  
Selda Özgen Özgacar
Keyword(s):  
Biological Activity ◽  
Chalcone Derivatives ◽  
Activity Screening

Recent Progress on the Discovery of Sirt2 Inhibitors for the Treatment of Various Cancers

2019 ◽  
Vol 19 (12) ◽  
pp. 1051-1058 ◽  
Author(s):  
Ting Wang ◽  
Zhuyu Xu ◽  
Yongping Lu ◽  
Jianyou Shi ◽  
Wenbo Liu ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Biological Activity ◽  
Inflammatory Response ◽  
Cell Cycle Regulation ◽  
Recent Progress ◽  
Biological Processes ◽  
Target Structure ◽  
Action Mechanism ◽  
Dependent Protein ◽  
Cycle Regulation

Sirtuins family is a class of NDA+ dependent protein deacetylases that play a key role in the regulation of several aspects of biological processes, such as cell cycle regulation, autophagy, immune and inflammatory response. Many studies have shown that sirtuins2 as a key player in the cancer pathway is of great significance in tumorigenesis. This review summarizes the newly discovered, in recent years, some SIRT2 inhibitors for cancer target structure, action mechanism, biological activity, substrate specificity, and signaling pathways.

scholarly journals Cytotoxicity Assay of 2,4-Dihydroxide-4’-Methoxychalcone Against Cervical (HeLa) Cancer Cell by MTT Assay

Biota ◽  
2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Novia Suryani ◽  
Sabirin Matsjeh ◽  
Mutmainah Mutmainah ◽  
Daratu Eviana Kusuma Putri Eviana Kusuma Putri ◽  
Damayanti Iskandar ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Biological Activity ◽  
Hela Cell ◽  
Cancer Cell ◽  
Mtt Assay ◽  
Antibacterial Activities ◽  
Target Compound ◽  
Chalcone Derivatives ◽  
Chalcone Derivative ◽  
Phenolic Group

Chalcone is one of the phenolic group secondary metabolic with numerous biological activity. Many studies have shown that chalcone derivatives compound has anticancer, anti-inflammatory, antimalarial, and antibacterial activities. The purpose of this research was to study the prediction potency unsaturated carbonyl system of chalcone derivative against the HeLa cell by MTT assay. Those activities assumed can inhibit the mechanism action of NF-kB that caused cervical cancer. The 2,4-dihydroxide-4’-methoxychalcone has done synthesis as a target compound by a sonochemical for 7 hours. The results showed that chalcone derivative most active against the HeLa cell.  

Sign in / Sign up

Export Citation Format

Share Document