Hybrid Pharmacophore Design, Molecular Docking, Synthesis, and Biological Evaluation of Novel Aldimine-Type Schiff Base Derivatives as Tubulin Polymerization Inhibitor

2018 ◽  
Vol 15 (3) ◽  
pp. e1700518 ◽  
Author(s):  
Alieh Ameri ◽  
Ghadamali Khodarahmi ◽  
Hamid Forootanfar ◽  
Farshid Hassanzadeh ◽  
Gholam-Hosein Hakimelahi
Keyword(s):  
Schiff Base ◽  
Molecular Docking ◽  
Biological Evaluation ◽  
Tubulin Polymerization ◽  
Schiff Base Derivatives ◽  
Polymerization Inhibitor ◽  
Tubulin Polymerization Inhibitor ◽  
Synthesis And Biological Evaluation

scholarly journals Synthesis and biological evaluation of 2-aryl-benzimidazole derivatives of dehydroabietic acid as novel tubulin polymerization inhibitors

RSC Advances ◽  
2018 ◽  
Vol 8 (31) ◽  
pp. 17511-17526 ◽  
Author(s):  
Ting-Ting Miao ◽  
Xu-Bing Tao ◽  
Dong-Dong Li ◽  
Hao Chen ◽  
Xiao-Yan Jin ◽  
...  
Keyword(s):  
Dehydroabietic Acid ◽  
Biological Evaluation ◽  
Benzimidazole Derivatives ◽  
Tubulin Polymerization ◽  
Polymerization Inhibitor ◽  
Tubulin Polymerization Inhibitor ◽  
Tubulin Polymerization Inhibitors ◽  
Synthesis And Biological Evaluation ◽  
Derivatives Of

A series of novel 2-aryl-benzimidazole derivatives of dehydroabietic acid were synthesized. Among them, compound 6j was found to be a potent tubulin polymerization inhibitor.

Synthesis and Biological Evaluation of 3-thiazolocoumarinyl Schiff-base Derivatives as Cholinesterase Inhibitors

2012 ◽  
Vol 80 (4) ◽  
pp. 605-615 ◽  
Author(s):  
Rabia Raza ◽  
Aamer Saeed ◽  
Mubeen Arif ◽  
Shamsul Mahmood ◽  
Muhammad Muddassar ◽  
...  
Keyword(s):  
Schiff Base ◽  
Cholinesterase Inhibitors ◽  
Biological Evaluation ◽  
Schiff Base Derivatives ◽  
Synthesis And Biological Evaluation

scholarly journals Synthesis, molecular docking and biological evaluation of bis-pyrimidine Schiff base derivatives

2017 ◽  
Vol 11 (1) ◽  
Author(s):  
Sanjiv Kumar ◽  
Siong Meng Lim ◽  
Kalavathy Ramasamy ◽  
Mani Vasudevan ◽  
Syed Adnan Ali Shah ◽  
...  
Keyword(s):  
Schiff Base ◽  
Molecular Docking ◽  
Biological Evaluation ◽  
Schiff Base Derivatives

scholarly journals Synthesis and Biological Evaluation of Three New Chitosan Schiff Base Derivatives

ACS Omega ◽  
2020 ◽  
Vol 5 (23) ◽  
pp. 13948-13954
Author(s):  
Nadia Q. Haj ◽  
Mohsin O. Mohammed ◽  
Luqman E. Mohammood
Keyword(s):  
Schiff Base ◽  
Biological Evaluation ◽  
Schiff Base Derivatives ◽  
Synthesis And Biological Evaluation ◽  
Chitosan Schiff Base
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