Efficacy of FGF‐2 in Periodontal Regeneration in a Case of Severe Intrabony Defect and Furcation Involvement With 15‐Month Follow‐up

Author(s):  
Shin‐ichi Takayama ◽  
Shinya Murakami
2019 ◽  
Vol 7 (1) ◽  
pp. 29 ◽  
Author(s):  
Zvi Artzi ◽  
Shiran Sudri ◽  
Ori Platner ◽  
Avital Kozlovsky

The purpose of this study is to evaluate and compare, retrospectively, the outcome of two different periodontal regeneration procedures in patients suffering from aggressive periodontitis (AgP). Twenty-eight patients were diagnosed with AgP, suffering from several intra-bony defects (IBD); that were treated by one of two periodontal regeneration techniques randomly assigned to each patient: a. guided tissue regeneration (GTR) or b. an application of extracted enamel matrix derivatives (EMD) combined with demineralized bone xenograft particles (DBX). Probing pocket depth (PPD), clinical attachment level (CAL), and gingival recession were recorded. Pre-treatment and follow-up (up to 10 years from the surgery) recordings were analyzed statistically within and between groups. A significant reduction was shown at time on PPD and CAL values, however, not between subject groups. CAL values decreased in all sites. At the EMD group (44 sites), CAL gain was 1.92 mm (±1.68) from pre-treatment to follow-up (p < 0.001) and at the GTR group (12 sites) CAL gain of 2.27 (±1.82) mm. In conclusion, 1–10 years observations have shown that surgical treatment of AgP patients by either GTR or by application of EMD/DBX results in similar successful clinical results.


2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
R. Ebru Tirali ◽  
Cagla Sar ◽  
Ufuk Ates ◽  
Metin Kizilkaya ◽  
S. Burcak Cehreli

Autotransplantation is a viable treatment option to restore esthetics and function impaired by abnormally shaped teeth when a suitable donors tooth is available. This paper describes the autotransplantation and 2-year follow-up of a supernumerary maxillary incisor as a replacement to a misaligned maxillary incisor with abnormal crown morphology and size. The supernumerary incisor was immediately autotransplanted into the extraction site of the large incisor and was stabilized with a bonded semirigid splint for 2 weeks. Fixed orthodontic therapy was initiated 3 months after autotransplantation. Ideal alignment of the incisors was accomplished after 6 months along with radiographic evidence of apical closure and osseous/periodontal regeneration. In autogenous tooth transplantation, a successful clinical outcome can be achieved if the cases are selected and treated properly.


2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Andrea Pilloni ◽  
Matteo Saccucci ◽  
Gabriele Di Carlo ◽  
Blerina Zeza ◽  
Marco Ambrosca ◽  
...  

Introduction.The aim of this retrospective study was to compare the clinical efficacy of four different surgical techniques in promoting periodontal regeneration in patients with infrabony defects: open flap debridement, application of enamel matrix derivatives (EMD), nanohydroxyapatite (nanoHA) application, and combined nanoHA and EMD application. Probing attachment level (PAL), pocket depth (PD), and position of gingival margin at completion of therapy (REC) were measured.Materials and Methods.Data were collected from 64 healthy patients (34 women and 30 men, mean age 37,7 years). Clinical indices were measured by a calibrated examiner at baseline and at 12, 18, and 24 months. The values obtained for each treatment were compared using nonparametric tests.Results.All treatments resulted in a tendency toward PD reduction over time, with improvements in REC and PAL. The differences in PD, REC, and PAL values at baseline compared with values after 12, 18, and 24 months were statistically significant for all treatments. Statistically significant differences in PAL and PD were detected between nanoHA and nanoHA + EMD at 12, 18, and 24 months.Conclusion.In this study, EMD and nanoHA used together in patients with infrabony periodontal lesions had better clinical efficacy than nanoHA alone, EMD alone, or open flap debridement.


2013 ◽  
Vol 54 (4) ◽  
pp. 243-250
Author(s):  
Akiyo Komiya-Ito ◽  
Sachiyo Tomita ◽  
Takashi Kinumatsu ◽  
Yoshihiro Fujimoto ◽  
Masatake Tsunoda ◽  
...  

2020 ◽  
pp. 7-8
Author(s):  
Valliammai Rajendran ◽  
David Kadakampally ◽  
Yamini Mannava ◽  
Deepa G Kamath ◽  
Ravalika N Kothuri

Introduction: Teeth with furcation involvement can be maintained in a state of function for a longer period of time if appropriately treated and if the patient is motivated adequately. This report highlights the effect of regenerative and resective therapy in the management of grade III furcation involvement. Observation: A 48 years old male patient was evaluated for furcation involvement with respect to the root canal treated lower right first molar tooth. Grade III furcation involvement was noted for which regenerative therapy was attempted with platelet rich fibrin (PRF) and bone grafts. After 2 years of follow up, the furcation involvement still persisted and patient had a complaint of food lodgement. Hence, resective osseous surgery (tunnel preparation) was done to make the furcation ease for maintaining oral hygiene. Commentary: In cases of periodontal loss, periodontal regenerative therapy must be the first treatment of choice. However, regeneration of grade III furcation involvement is more challenging and very few reports are available in the literature. Conclusion: The selection of cases for regenerative or resective therapy depends on the clinicians’ knowledge and practice. The ultimate goal of periodontal therapy is to provide a dentition that will function in health and comfort for life.


2019 ◽  
Vol 1 (1) ◽  
pp. 22-27

Purposes: The aim of this clinical report is to discuss the advantages and the steps of the root separation and resection approach in a maxillary molar with a class III furcation of the palatine root with a follow-up of 24 months. Case report: A patient with tooth mobility and bleeding after probing, was diagnosed with a Chronic Periodontitis Generalized Moderate and Localized Severe. Hygienic phase with oral hygiene instructions, scaling and root planning was performed. Due to class III furcation of the palatine root of the teeth 16 and some remaining pockets deepths, was decided to execute an apical repositioning flap on the 1st sextant among with the palatine root amputation combined with the endodontic treatment. During the surgical procedure, it was also performed a reduction of the palate thickness from teeth 15 to 17; in distal area of the 17 a distal wedged was performed in order to remove all the pockets. After the surgery, the patient was inserted in a long-lasting individualized supportive periodontal treatment.This case has a follow up of 24 months. Conclusions: Similar survival rates are described in the literature when we compared the root amputation with the dental implants survival rate, but the first one is cheaper and allows to keep the natural tooth. We can’t forget that the periodontitis is a risk factor of peri-implantitis. This clinical case shows that, with a high motivated patient and with the complete periodontal treatment, is possible to obtain excellent results with root separation and resection in maxillary molars class III.


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