scholarly journals Association of dietary fat intake and hepatocellular carcinoma among US adults

2021 ◽  
Author(s):  
Iman Moussa ◽  
Rena S. Day ◽  
Ruosha Li ◽  
Ahmed Kaseb ◽  
Prasun K. Jalal ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Dietary Fat ◽  
Fat Intake ◽  
Dietary Fat Intake

scholarly journals Dietary Fat Intake and Risk of Hepatocellular Carcinoma in Two Large Prospective Cohort Studies (FS13-07-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Wanshui Yang ◽  
Jing Sui ◽  
Yanan Ma ◽  
Tracey G Simon ◽  
Jessica L Petrick ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Dietary Fat ◽  
Dietary Fats ◽  
Fat Intake ◽  
Dietary Fat Intake ◽  
Saturated Fats ◽  
Dairy Fats

Abstract Objectives Epidemiological evidence of an association between dietary fat intake and hepatocellular carcinoma (HCC) risk is limited and inconclusive, particularly from prospective studies. Methods We prospectively examined intake of total and specific fats and major sources of dietary fats in relation to HCC risk within the Nurses’ Health Study and the Health Professionals Follow-up Study. Dietary fats were measured at baseline and updated approximately every 4 years using validated food frequency questionnaires. Cox proportional hazards regression models were used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) after adjusting for potential confounders. Results After an average follow-up of 28 years, 160 HCC cases including 85 women and 75 men were documented. According to food sources, there was a significant inverse association between vegetable fat intake and HCC risk (the highest vs. lowest quartile, HR = 0.61, 95% CI: 0.39–0.96, Ptrend = 0.02), but a suggestive positive association with animal or dairy fats. Replacing animal or dairy fats with an equivalent amount of vegetable fat was associated with a lower HCC risk (HR per 1-SD = 0.79, 95% CI: 0.65–0.97). According to fat subtypes, both monounsaturated and polyunsaturated fatty acids (PUFAs) including Omega-3 (the highest vs. lowest quartile, HR = 0.63, 95% CI: 0.41–0.96, Ptrend = 0.14) and Omega-6 PUFAs (HR = 0.54, 95% CI: 0.34–0.86, Ptrend = 0.02) were inversely associated with risk of HCC. The ratios of polyunsaturated and/or monounsaturated fat to saturated fat were all statistically inversely associated with HCC risk (all Ptrend ≤ 0.02). In addition, when replacing saturated fats with monounsaturated or polyunsaturated fats, the HR per 1-SD was 0.77 (95% CI: 0.64–0.92). Conclusions Higher intake of vegetable fats and polyunsaturated fatty acids may be associated with lower HCC risk. Replacing animal or dairy fats with vegetable fats or replacing saturated fats with polyunsaturated or monounsaturated fats may reduce the risk of HCC among US adults. Funding Sources This work was supported by grants from the National Institute of Health, American Cancer Society Research, Boston Nutrition Obesity Research Center Pilot and Feasibility Award.

Do Parent Anhedonia and Stress Contribute to Weight-related Parenting Practices, Child Dietary Fat Intake and Child BMI Percentile?

2013 ◽  
Author(s):  
Eleanor B. Tate ◽  
Susan M. Schembre ◽  
Gillian O'Reilly ◽  
Mary Ann Pentz ◽  
Genevieve Dunton
Keyword(s):  
Dietary Fat ◽  
Parenting Practices ◽  
Fat Intake ◽  
Dietary Fat Intake ◽  
Child Bmi

Comparison of Dietary Fat Intake Using Food Records vs. RBC Fatty Acid Biomarkers in a Multiethnic Population—The Federal Women Study

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1893-P
Author(s):  
AMBER B. COURVILLE ◽  
SHANNA BERNSTEIN ◽  
MIRELLA GALVAN-DE LA CRUZ ◽  
ANTHONY ONUZURUIKE ◽  
NIRUPA R. MATTHAN ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Dietary Fat ◽  
Fat Intake ◽  
Food Records ◽  
Dietary Fat Intake ◽  
Multiethnic Population ◽  
Fatty Acid Biomarkers

1734-P: High Dietary Fat Intake Exacerbates Insulin Resistance in a Type 2 Diabetes Genetic Mouse Model

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1734-P
Author(s):  
AUSTIN REILLY ◽  
SHIJUN YAN ◽  
ALEXA J. LONCHARICH ◽  
HONGXIA REN
Keyword(s):  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Mouse Model ◽  
Dietary Fat ◽  
Fat Intake ◽  
Dietary Fat Intake ◽  
Genetic Mouse Model

Dietary Fat Intake and Risk of Alzheimer’s Disease and Dementia: A Meta-Analysis of Cohort Studies

2018 ◽  
Vol 15 (9) ◽  
pp. 869-876 ◽  
Author(s):  
Yue Ruan ◽  
Jun Tang ◽  
Xiaofei Guo ◽  
Kelei Li ◽  
Duo Li
Keyword(s):  
Cohort Studies ◽  
Dietary Fat ◽  
Prospective Cohort ◽  
Meta Analysis ◽  
Saturated Fat ◽  
Fat Intake ◽  
Prospective Cohort Studies ◽  
Dietary Fat Intake ◽  
Dementia Risk ◽  
Saturated Fat Intake

Background: Epidemiological studies showed that dietary fat intake is associated with Alzheimer’s disease (AD) and dementia risk, however, the association remain inconsistent. This metaanalysis aimed to systematically examine the association of dietary fat intake with AD and dementia risk. Methods: We have systematically searched PubMed, Embase and the Cochrane Library up to May 1st 2017. Prospective cohort studies were included if they reported on the association of dietary fat intake with AD and dementia risk. Multivariate-adjusted relative risks (RRs) for the highest versus lowest category were pooled by using a random-effects model. Results: A total of 8630 participants and 633 cases from four independent prospective cohort studies were included in the present meta-analysis. A higher dietary saturated fat intake was significantly associated with an increased risk of 39% and 105% for AD (RR: 1.39; 95% CI: 1.00, 1.94) and dementia (RR: 2.05; 95% CI: 1.06, 3.98), respectively. Dose-response analysis indicated a 4 g/day increment of saturated fat intake was related to 15% higher risk of AD (RR: 1.15; 95% CI: 1.01, 1.31). However, there was no significant association found between dietary intake of total, monounsaturated, polyunsaturated fat and AD or dementia risk. Conclusions: This meta-analysis provides significant evidence of positive association between higher saturated fat intake and AD and dementia risk.

scholarly journals Dietary fat intake and liver cancer incidence: A population‐based cohort study in Chinese men

2021 ◽  
Vol 148 (12) ◽  
pp. 2982-2996
Author(s):  
Xiao‐Wei Ji ◽  
Jing Wang ◽  
Qiu‐Ming Shen ◽  
Zhuo‐Ying Li ◽  
Yu‐Fei Jiang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Liver Cancer ◽  
Cancer Incidence ◽  
Dietary Fat ◽  
Population Based ◽  
Fat Intake ◽  
Chinese Men ◽  
Dietary Fat Intake
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