scholarly journals Impact of portal hypertension on short‐ and long‐term outcomes after liver resection for intrahepatic cholangiocarcinoma: A propensity score matching analysis

2021 ◽  
Author(s):  
Jun Fu ◽  
Qinjunjie Chen ◽  
Yuyan Yu ◽  
Wuyi You ◽  
Zongren Ding ◽  
...  
Keyword(s):  
Portal Hypertension ◽  
Liver Resection ◽  
Propensity Score ◽  
Propensity Score Matching ◽  
Intrahepatic Cholangiocarcinoma ◽  
Long Term Outcomes ◽  
Propensity Score Matching Analysis ◽  
Short And Long Term

Hepatectomy Provides Good Long-Term Outcomes for Hepatocellular Carcinoma Patients With Portal Hypertension: A Propensity Score Matching Analysis

2020 ◽  
Author(s):  
Xiwen Wu ◽  
Wei Chen ◽  
Bin Chen ◽  
Wenxuan Xie ◽  
Shutong Wang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Portal Hypertension ◽  
Propensity Score ◽  
Propensity Score Matching ◽  
Venous Invasion ◽  
Long Term Outcomes ◽  
Propensity Score Matching Analysis ◽  
Initial Hepatectomy ◽  
Baseline Characteristics

Abstract Background: The role of hepatectomy in hepatocellular carcinoma (HCC) with portal hypertension (PH) remains controversial. This study aimed to evaluate the effect of hepatectomy on overall survival (OS) of HCC patients with PH.Methods: A total of 1651 HCC initially treated with hepatectomy were retrospectively reviewed and divided into PH group (n=157) or non-PH group (n=1494). Propensity score matching (PSM) was conducted to match the baseline characteristics of the PH group and non-PH group. Results: The PH group presented a similar OS (p=0.29) and recurrence free survival (RFS) (p=0.83) compared with non-PH group after initial hepatectomy before PSM. After PSM processing, the baseline characteristics were highly comparable for both groups (133 patients in each group). The PH group also presented a similar OS (p=0.81) and RFS (p=0.65) compared with non-PH group after initial hepatectomy. After PSM, multivariate analysis identified tumor size (>5 cm) (p=0.02), macro-venous invasion (p < 0.001), AST (>37 U/L) (p =0.008) as independent risk factors for OS.Conclusions: Hepatectomy provides good long-term outcomes for HCC patients with PH. PH should not be regarded as a contraindication for hepatectomy in HCC patients.

Short- and Long-term Outcomes after Robotic and Laparoscopic Liver Resection for Malignancies: A Propensity Score-Matched Study

2019 ◽  
Vol 43 (6) ◽  
pp. 1594-1603 ◽  
Author(s):  
Chetana Lim ◽  
Chady Salloum ◽  
Antonella Tudisco ◽  
Claudio Ricci ◽  
Michael Osseis ◽  
...  
Keyword(s):  
Liver Resection ◽  
Propensity Score ◽  
Laparoscopic Liver Resection ◽  
Long Term Outcomes ◽  
Short And Long Term ◽  
Matched Study

Short- and Long-Term Outcomes of Liver Resection for Intrahepatic Cholangiocarcinoma Associated with the Metabolic Syndrome

2019 ◽  
Vol 43 (8) ◽  
pp. 2048-2060 ◽  
Author(s):  
Christian Hobeika ◽  
François Cauchy ◽  
Nicolas Poté ◽  
Pierre-Emmanuel Rautou ◽  
François Durand ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Liver Resection ◽  
Intrahepatic Cholangiocarcinoma ◽  
Long Term Outcomes ◽  
The Metabolic Syndrome ◽  
Short And Long Term
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