scholarly journals Indocyanine green is a sensitive adjunct in the identification and surgical management of local and metastatic hepatoblastoma

2021 ◽  
Author(s):  
Charissa M. Lake ◽  
Alexander J. Bondoc ◽  
Anasua Roshni Dasgupta ◽  
Todd M. Jenkins ◽  
Alexander J. Towbin ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Surgical Management ◽  
Green Is

scholarly journals Near-infrared mapping with indocyanine green is associated with an increase in oncological margin length in minimally invasive segmentectomy

2019 ◽  
Vol 157 (5) ◽  
pp. 2029-2035 ◽  
Author(s):  
Meera Mehta ◽  
Yogita S. Patel ◽  
Kazuhiro Yasufuku ◽  
Thomas Kenneth Waddell ◽  
Yaron Shargall ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Indocyanine Green ◽  
Near Infrared ◽  
Green Is

P155 REAL-TIME EVALUATION OF THE GASTRIC CONDUIT BASED ON THE REGIONAL O2 SATURATION (%) AND TOTAL HEMOGLOBIN INDEX IN THORACIC ESOPHAGECTOMY

2019 ◽  
Vol 32 (Supplement_2) ◽  
Author(s):  
Fujita Takeo ◽  
Sato Kazuma ◽  
Hirano Yuki ◽  
Fujiwara Hisashi ◽  
Daiko Hiroyuki
Keyword(s):  
Indocyanine Green ◽  
Anastomotic Leakage ◽  
Evaluation Method ◽  
Mean Value ◽  
Gastric Conduit ◽  
Green Is ◽  
Mean Values ◽  
Total Hemoglobin ◽  
Distal Side ◽  
Optimal Site

Abstract Aim Evaluation of blood supply of gastric conduit is one of the most importance parameter in thoracic esophagectomy. Evaluation with indocyanine green is the most popular evaluation method. However, indocyanine green does not objecctive values with Herein we introduce the new evaluation method based on the regional SO2(%) and Total hemoglobin index in thoracic esophagectomy. Background and methods: Between February to July 2018, we evaluated 56 patients underwent thoracic esophagectomy for esophageal cancer. Regional O2 saturation level (rSO%) and total hemoglobin indexes (T-HbI) of gastric conduit was evaluated using the ToccareTM (ASTEM Co. Ltd Tokyo, Japan) to determine the optimal site of anastomosis on gastric conduit. Results Fifty-two patients were eligible in this study. Mean value of the rSO2(%)/T-HbI were 57.6%/0.22 at the anal side of the gastric conduit where sufficient feeding arteries were existed from right gastroepiploic artery and vein. On the other hand, mean values of the rSO2(%)/T-HbI were 59.4%/0.28 (p<0.05) at the distal side of the gastric conduit where direct feeding artery from right gastroepiploic vessel was terminated. Then, mean values of rSO2(%)/T-HbI were 46.3%/0.34 (p<0.05) at the tip of the gastric conduit, which consisted to the gradual congestion was happened prior to the tissue oxygenation in the gastric conduit. There were 1 patient which found anastomotic leakage (1.9%) among 56 patients. Conclusion Evaluation of the regional SO2(%) and total hemoglobin index of the gastric conduit was non-invasiveness procedure and useful to easily determine the optimal site of anastomotic level to minimize the incidence of anastomotic leakage in thoracic esophagectomy.

Sentinel Lymphadenectomy in Vulvar Cancer Using Near-Infrared Fluorescence From Indocyanine Green Compared With Technetium 99m Nanocolloid

2017 ◽  
Vol 27 (4) ◽  
pp. 805-812 ◽  
Author(s):  
Philipp Soergel ◽  
Hermann Hertel ◽  
Anna Kaarina Nacke ◽  
Rüdiger Klapdor ◽  
Thorsten Derlin ◽  
...  
Keyword(s):  
Lymph Node ◽  
Confidence Interval ◽  
Lymph Nodes ◽  
Indocyanine Green ◽  
Near Infrared ◽  
Vulvar Cancer ◽  
Sentinel Lymph Nodes ◽  
Infrared Band ◽  
Green Is ◽  
Patent Blue

ObjectiveNowadays, sentinel diagnostic is performed using technetium 99m (99mTc) nanocolloid as a radioactive marker and sometimes patent blue. In the last years, indocyanine green has been evaluated for sentinel diagnostic in different tumor entities. Indocyanine green is a fluorescent molecule that emits a light signal in the near-infrared band after excitation. Our study aimed to evaluate indocyanine green compared with the criterion-standard99mTc-nanocolloid.MethodsWe included patients with primary, unifocal vulvar cancer of less than 4 cm with clinically node-negative groins in this prospective trial. Sentinel diagnostic was carried out using99mTc-nanocolloid, indocyanine green, and patent blue. We examined each groin for light signals from the near-infrared band, for radioactivity, and for blue staining. A sentinel lymph node was defined as a99mTc-nanocolloid–positive lymph node. All sentinel lymph nodes and all additional blue or fluorescent lymph nodes were excised and tested and then sent for histologic examination.ResultsIn all, 27 patients were included in whom we found 91 sentinel lymph nodes in 52 groins. All these lymph nodes were positive for indocyanine green, also giving a sensitivity of 100% (95% confidence interval [CI], 96.0%–100%) compared with99mTc-nanocolloid. Eight additional lymph nodes showed indocyanine green fluorescence but no99mTc positivity, so that the positive predictive value was 91.9% (95% confidence interval, 84.6%–96.5%). In 1 patient, a false-negative sentinel missed by all 3 modalities was found.ConclusionsOur results show that indocyanine green is a promising approach for inguinal sentinel identification in vulvar cancer with a similar sensitivity as radioactive99mTc-nanocolloid and worth to be evaluated in further studies.

EVALUATION OF GASTRIC CONDUIT BLOOD SUPPLY WITH FLUORESCENT ANGIOGRAPHY WITH INDOCYANINE GREEN AFTER ESOPHAGECTOMY FOR CANCER

2019 ◽  
Vol 65 (1) ◽  
pp. 94-98
Author(s):  
Vladimir Lyadov ◽  
S. Gamayunov ◽  
V. Karov ◽  
T. Eynullaeva
Keyword(s):  
Indocyanine Green ◽  
Blood Supply ◽  
Gastric Tube ◽  
Objective Evaluation ◽  
Control Group ◽  
Short Term ◽  
Intraoperative Bleeding ◽  
Green Is ◽  
Esophagectomy For Cancer ◽  
Severe Grade

Anastomotic leak and conduit necrosis are severe complications after esophagectomy. Fluorescent angiography with indocyanine green provides an opportunity to objectively evaluate conduit perfusion and, potentially, reduce the number of leaks. Material and methods. We analyzed short-term outcomes of 26 esophagectomies performed with laser fluorescent evaluation of conduit perfusion. All patients had esophagogastic anastomosis, 14 in the neck, 12 in the pleural cavity. Conduit perfusion was assessed 30 sec after intravenous bolus injection of 6 mg of indocya-nine green with SPY2000 laser technology. The results were compared with short-term outcomes of 35 esophagectomies performed without fluorescent assessment of gastric tube perfusion. Results. There were 6 leaks or conduit necrosis in control group while in the ICG group there were only 2 leaks on the neck: 1 in a patient with a massive intraoperative bleeding and shock, 1 in a patient with severely compromised blood supply of the gastric tube tip according to ICG imaging. No cases of conduit necrosis were found, which led to significantly lower number of severe (grade III-V Dindo-Clavien) complications, p=0,033. Conclusion Laser fluorescent angiography with indocyanine green is a useful tool which affords an objective evaluation of gastric tube perfusion and, potentially, reduces the number of severe postoperative complications after esophagectomy.

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