scholarly journals Next‐generation sequencing of tissue and circulating tumor DNA: Resistance mechanisms to EGFR targeted therapy in a cohort of patients with advanced non‐small cell lung cancer

2021 ◽  
Author(s):  
Yujun Zhang ◽  
Liwen Xiong ◽  
Fangfang Xie ◽  
Xiaoxuan Zheng ◽  
Ying Li ◽  
...  
2020 ◽  
Author(s):  
Luiz H Araujo ◽  
Carlos Gil Ferreira ◽  
Clarissa S Baldotto ◽  
Clarissa Mathias ◽  
Gilberto Castro ◽  
...  

The objective of this review is to address the barriers limiting access to next-generation sequencing (NGS) of circulating tumor DNA (ctDNA) for metastatic nonsquamous non-small cell lung cancer in Brazil and to propose its implementation in practice. A selected panel of lung cancer experts was provided with relevant prompts to address at a conference; a paper was then compiled on the topic. The authors propose specific and realistic recommendations for implementing access to ctDNA NGS. Further, the authors address all barriers and impediments mentioned within this review. There is a great need to increase ctDNA NGS for cancer care in Brazil. Adapting the current cancer testing framework is essential to expanding the use of this tool.


2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e23021-e23021 ◽  
Author(s):  
Stephen R Fairclough ◽  
Oliver A. Zill ◽  
Darya Chudova ◽  
Christine Elaine Lee ◽  
Richard Burnham Lanman ◽  
...  

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