scholarly journals Elevated serum substance P level as a predictive marker for moderately emetogenic chemotherapy‐induced nausea and vomiting: A prospective cohort study

2020 ◽  
Author(s):  
Hyung Soon Park ◽  
Hye Sung Won ◽  
Ho Jung An ◽  
Sung Shim Cho ◽  
Hyun Ho Kim ◽  
...  
Keyword(s):  
Cohort Study ◽  
Substance P ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Elevated Serum ◽  
Predictive Marker ◽  
Emetogenic Chemotherapy ◽  
Nausea And Vomiting ◽  
Moderately Emetogenic Chemotherapy

scholarly journals Chemotherapy-induced nausea and vomiting in patients with breast cancer: a prospective cohort study

Breast Cancer ◽  
2019 ◽  
Vol 27 (1) ◽  
pp. 122-128 ◽  
Author(s):  
Yoichi Naito ◽  
Yuichiro Kai ◽  
Takashi Ishikawa ◽  
Tomoyuki Fujita ◽  
Kanou Uehara ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Nausea And Vomiting

scholarly journals Oocyte meiotic spindle morphology is a predictive marker of blastocyst ploidy—a prospective cohort study

2020 ◽  
Vol 113 (1) ◽  
pp. 105-113.e1 ◽  
Author(s):  
Liza Tilia ◽  
Michael Chapman ◽  
Suha Kilani ◽  
Simon Cooke ◽  
Christos Venetis
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Predictive Marker ◽  
Meiotic Spindle

scholarly journals Nausea and vomiting in pregnancy is not just ‘morning sickness’: data from a prospective cohort study in the UK

2020 ◽  
Vol 70 (697) ◽  
pp. e534-e539
Author(s):  
Roger Gadsby ◽  
Diana Ivanova ◽  
Emma Trevelyan ◽  
Jane L Hutton ◽  
Sarah Johnson
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Early Pregnancy ◽  
Prospective Cohort ◽  
Nausea And Vomiting ◽  
Morning Sickness ◽  
Before And After ◽  
Symptom Patterns ◽  
The Uk ◽  
In Pregnancy

BackgroundNausea and vomiting in pregnancy is usually called ‘morning sickness’. This is felt by sufferers to trivialise the condition. Symptoms have been described as occurring both before and after noon, but daily symptom patterns have not been clearly described and statistically modelled to enable the term ‘morning sickness’ to be accurately analysed.AimTo describe the daily variation in nausea and vomiting symptoms during early pregnancy in a group of sufferers.Design and settingA prospective cohort study of females recruited from 15 May 2014 to 17 February 2017 by Swiss Precision Diagnostics (SPD) Development Company Limited, which was researching hormone levels in early pregnancy and extended its study to include the description of pregnancy symptoms.MethodDaily symptom diaries of nausea and vomiting were kept by females who were trying to conceive. They also provided daily urine samples, which when analysed enabled the date of ovulation to be determined. Data from 256 females who conceived during the first month of the study are included in this article. Daily symptom patterns and changes in daily patterns by week of pregnancy were modelled. Functional data analysis was used to produce estimated symptom probability functions.ResultsThere was a peak probability of nausea in the morning, a lower but sustained probability of nausea throughout the day, and a slight peak in the evening. Vomiting had a defined peak incidence in the morning.ConclusionReferring to nausea and vomiting in pregnancy as simply ‘morning sickness’ is inaccurate, simplistic, and therefore unhelpful.

scholarly journals Comparing effectiveness of Metoclopramide alone versus its combination with Dexamethasone for prevention of postoperative nausea and vomiting after thyroidectomy at Menelik II Hospital, Addis Ababa, Ethiopia: a prospective cohort study

2019 ◽  
Author(s):  
Tamiru Tilahun ◽  
Adugna Aregawi ◽  
Temesgen Bati Gelgelu
Keyword(s):  
Cohort Study ◽  
Side Effects ◽  
Prospective Cohort Study ◽  
Postoperative Nausea ◽  
Prospective Cohort ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting ◽  
P Value ◽  
Sample Population ◽  
Post Operative Nausea

Abstract Background Postoperative nausea and vomiting (PONV) is a common post- operative unpleasant experience and also common following thyroidectomy that may cause for hematoma and post-operative airway obstruction. Several agents have been tried to reduce severity and incidence PONV.This study intended to compare effectiveness of Metoclopramide alone and its combination with Dexamethasone for prevention of PONV after thyroidectomy at Menelik II Hospital.Methods Prospective cohort study was conducted on 76 American Society of Anesthesiologist (ASA) class I and II, adult patients undergone thyroidectomy. A systematic random sampling was applied to identify sample population through skip interval till required sample size was achieved. Study participants were grouped as Group = M (Metoclopramide alone) and Group = MD (Metoclopramide plus Dexamethasone).Following study participant received either 10 mg Metoclopramide or 5mg Metoclopramide plus 4mg Dexamethasone, PONV was recorded at 6, 12 and 24 hours post operatively. Continuous variables were expressed as mean ± SD or median-IQR as appropriate. Analysis was done by independent two sample t test, Manny Whitney U test and χ2 or fisher exact test. P-Value <0.05 was considered as statistically significant.Results The overall incidence of PONV with in the first 24 hours was significantly higher in Group M as compared to Group MD, 24(63.15%) versus 9 (23.68%) respectively with a P-value of < .01. Although difference was insignificant, severity of nausea at 6th, 12th and 24th was still higher in Group M. From side effects, Sedation was significantly lower in Group MD 6 (15.79%) versus 15 (39.47%) with a P-value of <.05. Despite difference was insignificant headache was found higher in Group M 10 (26.31) vs. 6 (10.52) respectively.Conclusions 5mg Metoclopramide combined with 4mg Dexamethasone has significant effects for prophylaxis of post-operative nausea and vomiting after thyroidectomy. Some side effects of drugs were also significantly reduced in combination group.

Sign in / Sign up

Export Citation Format

Share Document