scholarly journals Prognostic significance for colorectal carcinoid tumors based on the 8th edition TNM staging system

2020 ◽  
Vol 9 (21) ◽  
pp. 7979-7987
Author(s):  
Piqing Gong ◽  
Chunhua Chen ◽  
Zhan Wang ◽  
Xukun Zhang ◽  
Wenxin Hu ◽  
...  
Keyword(s):  
Prognostic Significance ◽  
Staging System ◽  
Tnm Staging ◽  
Carcinoid Tumors ◽  
Tnm Staging System ◽  
8Th Edition ◽  
Colorectal Carcinoid

The Updated AJCC/TNM Staging System for Papillary Thyroid Cancer (8th Edition): From the Perspective of Genomic Analysis

2018 ◽  
Vol 42 (11) ◽  
pp. 3624-3631 ◽  
Author(s):  
Kyubo Kim ◽  
Jin Hwan Kim ◽  
Il Seok Park ◽  
Young Soo Rho ◽  
Gee Hwan Kwon ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Genomic Analysis ◽  
Staging System ◽  
Tnm Staging ◽  
Papillary Thyroid ◽  
Tnm Staging System ◽  
8Th Edition

HOW DOES THE AJCC/TNM STAGING SYSTEM 8TH EDITION PERFORM IN THYROID CANCER AT A MAJOR MIDDLE EASTERN MEDICAL CENTER?

2020 ◽  
Author(s):  
Ali S. Alzahrani ◽  
Lina Albalawi ◽  
Sedra Mazi ◽  
Noha Mukhtar ◽  
Hadeel AlJamei ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Medical Center ◽  
Middle Eastern ◽  
Staging System ◽  
Tnm Staging ◽  
Tnm Staging System ◽  
8Th Edition

RA09.08: EVALUATION OF THE EIGHTH YPTNM CLASSIFICATION SYSTEM IN ESOPHAGEAL CANCER PATIENTS

2018 ◽  
Vol 31 (Supplement_1) ◽  
pp. 41-42
Author(s):  
Motoo Nomura ◽  
Shigeru Tsunoda ◽  
Katsuyuki Sakanaka ◽  
Masashi Tamaoki ◽  
Yusuke Amanuma ◽  
...  
Keyword(s):  
Staging System ◽  
Tnm Staging ◽  
Prognostic Impact ◽  
Poor Prognostic Factor ◽  
Pathologic Stage ◽  
7Th Edition ◽  
Tnm Staging System ◽  
Staging Systems ◽  
Prognostic Group ◽  
8Th Edition

Abstract Background The 7th edition of the Union for International Cancer Control (UICC) TNM staging system is based on pathologic data from esophageal cancers treated by surgery alone. In the 8th edition of UICC-TNM staging system, there is no information available for treatment modality (surgery alone or neoadjuvant therapy [NAC] followed by surgery [NAC-S]), although clinical stage, neoadjuvant pathologic stage, and pathologic stage were analyzed and identified. The objective of this study was to evaluate the prognostic impact of the new staging system on esophageal squamous cell cancer (ESCC) patients treated by NAC-S. Methods Database of 140 consecutive ESCC patients in our hospital was retrospectively restaged in 7th and 8th UICC-TNM system. The prognostic impacts of pathologic stage after NAC according to the both staging systems were compared. Results The median follow-up period was 4.8 years (range 0.2–9.7), with 49 patients dead at the time of analysis. In 7th edition, the 3-year overall survival rates (3y-OS) of ypStages 0, I, II, III, and IV were 100%, 93.5%, 93.5%, 43.9%, and 0.0%, respectively. In 8th edition, the 3y-OS of ypStages 0, I, II, III, and IV were 100%, 96.5%, 90.2%, 51.7%, and 29.6%, respectively. There were no marked differences between 7th and 8th edition in the prognoses. The both editions poorly distinguish the prognoses of ypStages 0, I, and II. For pathological prognostic group in 7th edition, the 3y-OS of Groups 0, I, II, III, and IV were 100%, 97.0%, 90.6%, 43.9%, and 0.0%, respectively. For pathological prognostic group in 8th edition, the 3y-OS of Groups 0, I, II, III, and IV were 100%, 96.7%, 89.8%, 51.7%, and 29.6%, respectively. For patients with ypStages 0-II, pretreatment higher CEA was poor prognostic factor (HR 7.1, 95% confidence interval 1.9–25.9). Conclusion Our study indicates the problem that the ypStage in the 8th TNM staging system poorly distinguish the prognoses of ypStages 0, I, and II in patients undergoing NAC-S. Additional study is needed to evaluate the role of ypStage 0-II incorporation of new prognostic factors. Disclosure All authors have declared no conflicts of interest.

scholarly journals Is Preoperative Fibrinogen Associated with the Survival Prognosis of Gastric Cancer Patients? A Multi-centered, Propensity Score-Matched Retrospective Study

2019 ◽  
Vol 44 (1) ◽  
pp. 213-222
Author(s):  
Lin-Yong Zhao ◽  
Yong-Liang Zhao ◽  
Jun-Jiang Wang ◽  
Qi-Di Zhao ◽  
Wen-Qi Yi ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Propensity Score ◽  
Cancer Patients ◽  
Prognostic Significance ◽  
Staging System ◽  
Tnm Staging ◽  
Plasma Fibrinogen ◽  
Tnm Staging System ◽  
N Stage ◽  
Gastric Cancer Patients

Abstract Background The prognostic significance of preoperative plasma fibrinogen in patients with operable gastric cancer remains under debate. This study aimed to elucidate the prognostic value of fibrinogen in gastric cancer patients underwent gastrectomy. Methods A total of 4351 patients with gastric cancer collected from three comprehensive medical centers were retrospectively evaluated. Patients were categorized by minimum P value using X-tile, while the baseline confounders for fibrinogen was balanced through propensity score matching (PSM). The relationships between fibrinogen and other clinicopathologic features were evaluated, and nomogram was constructed to assess its prognostic improvement compared with TNM staging system. Results Fibrinogen was significantly correlated with macroscopic type, tumor differentiation, tumor size, and T and N stage. The factors, fibrinogen and T stage as well as N stage, were identified to be independent prognostic factors after PSM. Nomogram based on fibrinogen demonstrated a smaller Akaike information criterion (AIC) and a larger concordance index (C-index) than TNM staging system, illustrating that fibrinogen might be able to improve the prognostic accuracy. Conclusions Preoperative plasma fibrinogen levels in gastric cancer patients were significantly correlated with tumor progression, which could be regarded as a reliable marker for survival prognostic prediction.

Sign in / Sign up

Export Citation Format

Share Document