scholarly journals Health‐related quality of life in long‐term prostate cancer survivors after nerve‐sparing and non‐nerve‐sparing radical prostatectomy—Results from the multiregional PROCAS study

2020 ◽  
Vol 9 (15) ◽  
pp. 5416-5424
Author(s):  
Salome Adam ◽  
Eva Martin‐Diener ◽  
Bertrand Camey ◽  
Céline Egger Hayoz ◽  
Isabelle Konzelmann ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Nerve Sparing ◽  
Health Related Quality ◽  
Prostate Cancer Survivors ◽  
Related Quality ◽  
Health Related

PD18-03 LONG-TERM HEALTH RELATED QUALITY OF LIFE IN PROSTATE CANCER PATIENTS REQUIRING RADIOTHERAPY AFTER RADICAL PROSTATECTOMY

2017 ◽  
Vol 197 (4S) ◽  
Author(s):  
Louis Aliperti ◽  
Dattatraya Patil ◽  
Akanksha Mehta ◽  
Christopher Filson ◽  
Catrina Crociani ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Cancer Patients ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Long-Term Outcomes Among Localized Prostate Cancer Survivors: Health-Related Quality-of-Life Changes After Radical Prostatectomy, External Radiation, and Brachytherapy

2005 ◽  
Vol 23 (12) ◽  
pp. 2772-2780 ◽  
Author(s):  
David C. Miller ◽  
Martin G. Sanda ◽  
Rodney L. Dunn ◽  
James E. Montie ◽  
Hector Pimentel ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Urinary Incontinence ◽  
Radical Prostatectomy ◽  
External Radiation ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Purpose We sought to elucidate long-term changes in health-related quality-of-life (HRQOL) outcomes by prospectively re-evaluating a well-characterized cohort of prostate cancer (PC) survivors 4 to 8 years after primary treatment. Patients and Methods Patients who had been evaluated previously at a median of 2.6 years after radical prostatectomy (RP), external radiation (three-dimensional conformal radiation therapy [3-D CRT]), or brachytherapy (BT) were recontacted at a median of 6.2 years after treatment. The clinical relevance of long-term HRQOL impairment among survivors was established by comparison with controls of similar age. Factors associated with HRQOL changes during this interval were evaluated. Results Of the 964 eligible men, 709 (73.5%) completed measurable questionnaires. In four domains (urinary irritative-obstructive, urinary incontinence, bowel, and sexual), significant HRQOL differences were detected for at least one of the therapy groups, compared with controls (all P < .05). During the 4-year interval, significant improvement was observed for the urinary irritative-obstructive (P < .0001) and bowel (P < .0001) domains among BT patients, whereas urinary incontinence HRQOL worsened for both the BT (P = .0017) and 3-D CRT (P = .0008) treatment groups. Overall sexual HRQOL deteriorated for the 3-D CRT cohort (P = .0017), as well as for controls (P = .0136). Among RP patients, significant HRQOL changes were not observed. Conclusion During a 4-year interval from earlier to longer-term phases of PC treatment survivorship, sexual, urinary, and bowel dysfunction remain significant concerns among early-stage PC treatment survivors, compared with control men. Although postprostatectomy HRQOL remains relatively stable during this interval, disease-specific HRQOL continues to evolve among men treated with BT and 3-D CRT.

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