scholarly journals Relevance and prognostic ability of Twist, Slug and tumor spread through air spaces in lung adenocarcinoma

2020 ◽  
Vol 9 (6) ◽  
pp. 1986-1998 ◽  
Author(s):  
Ao Liu ◽  
Xiao Sun ◽  
Jin Xu ◽  
Yunpeng Xuan ◽  
Yandong Zhao ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Tumor Spread ◽  
Spread Through Air Spaces

Relationship between Twist, Slug with Tumor Spread Through Air Spaces in Lung Adenocarcinoma

2019 ◽  
Author(s):  
Ao Liu ◽  
Xiao Suna ◽  
Jin Xu ◽  
Yunpeng Xuan ◽  
Feng Hou ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Tumor Spread ◽  
Spread Through Air Spaces

scholarly journals Relationship between stromal cells and tumor spread through air spaces in lung adenocarcinoma

2019 ◽  
Vol 10 (2) ◽  
pp. 256-267 ◽  
Author(s):  
Xie Qiu ◽  
Donglai Chen ◽  
Yangyang Liu ◽  
Shanzhou Duan ◽  
Fuquan Zhang ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Stromal Cells ◽  
Tumor Spread ◽  
Spread Through Air Spaces

scholarly journals Meta-analysis of association between CT-based features and tumor spread through air spaces in lung adenocarcinoma

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Qifan Yin ◽  
Huien Wang ◽  
Hongshang Cui ◽  
Wenhao Wang ◽  
Guang Yang ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Tumor Size ◽  
Large Scale ◽  
Meta Analysis ◽  
Systematic Research ◽  
Ct Image ◽  
Significant Independent Predictor ◽  
Tumor Spread ◽  
Solid Nodule ◽  
Spread Through Air Spaces

Abstract Objective Spread through air space (STAS) is a novel invasive pattern of lung adenocarcinoma and is also a risk factor for recurrence and worse prognosis of lung adenocarcinoma after sublobar resection. The aims of this study are to evaluate the association between computed tomography (CT)-based features and STAS for preoperative prediction of STAS in lung adenocarcinoma, eventually, which could help us choose appropriate surgical type. Methods Systematic research was conducted to search for studies published before September 1, 2019. The association between CT-based features of radiological tumor size>2 cm、pure solid nodule、 part-solid nodule or Percentage of solid component (PSC)>50% and STAS was evaluated. According to rigorous inclusion and exclusion criteria. Eight studies including 2385 patients published between 2015 and 2018 were finally enrolled in our meta-analysis. Results Our results clearly depicted that there is no significant relationship between radiological tumor size>2 cm and STAS with the combined OR of 1.47(95% CI:0.86–2.51). Meta-analysis of 3 studies showed that pure solid nodule in CT image were more likely to spread through air spaces with pooled OR of 3.10(95%CI2.17–4.43). Meta-analysis of 5 studies revealed the part-solid nodule in CT image may be more likely to appear STAS in adenocarcinoma (ADC) (combined OR:3.10,95%CI:2.17–4.43). PSC>50% in CT image was a significant independent predictor in the diagnosis of STAS in ADC from our meta-analysis with combined OR of 2.95(95%CI:1.88–4.63). Conclusion In conclusion, The CT-based features of pure solid nodule、part-solid nodule、PSC>50% are promising imaging biomarkers for predicting STAS in ADC and may substantially influence the choice of surgical type. In future, more studies with well-designed and large-scale are needed to confirm the conclusion.

Preoperative bronchial cytology for the assessment of tumor spread through air spaces in lung adenocarcinoma resection specimens

2020 ◽  
Vol 128 (4) ◽  
pp. 278-286 ◽  
Author(s):  
Mayra A. Medina ◽  
Allison M. Onken ◽  
Constance Margerie‐Mellon ◽  
Benedikt H. Heidinger ◽  
Yigu Chen ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Tumor Spread ◽  
Spread Through Air Spaces

scholarly journals Tumor Spread through Air Spaces Affects the Recurrence and Overall Survival in Patients with Lung Adenocarcinoma >2 to 3 cm

2017 ◽  
Vol 12 (7) ◽  
pp. 1052-1060 ◽  
Author(s):  
Chenyang Dai ◽  
Huikang Xie ◽  
Hang Su ◽  
Yunlang She ◽  
Erjia Zhu ◽  
...  
Keyword(s):  
Overall Survival ◽  
Lung Adenocarcinoma ◽  
Tumor Spread ◽  
Spread Through Air Spaces

Novel imprint cytological classification is correlated with tumor spread through air spaces in lung adenocarcinoma

Lung Cancer ◽  
2020 ◽  
Vol 148 ◽  
pp. 62-68
Author(s):  
Toru Kimura ◽  
Harumi Nakamura ◽  
Akiisa Omura ◽  
Akihiro Ike ◽  
Takashi Hiroshima ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Tumor Spread ◽  
Spread Through Air Spaces
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