scholarly journals Cigarette smoking increases the risk of nasopharyngeal carcinoma through the elevated level of IgA antibody against Epstein‐Barr virus capsid antigen: A mediation analysis

2020 ◽  
Vol 9 (5) ◽  
pp. 1867-1876
Author(s):  
Wan‐Lun Hsu ◽  
Yin‐Chu Chien ◽  
Yen‐Tsung Huang ◽  
Kelly J. Yu ◽  
Jenq‐Yuh Ko ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Cigarette Smoking ◽  
Mediation Analysis ◽  
Elevated Level ◽  
Epstein Barr Virus ◽  
Virus Capsid ◽  
Barr Virus ◽  
Iga Antibody ◽  
Epstein Barr ◽  
Virus Capsid Antigen

ANTIBODIES TO EPSTEIN-BARR VIRUS CAPSID ANTIGEN AND EARLY ANTIGEN IN NASOPHARYNGEAL CARCINOMA AND COMPARISON GROUPS

1977 ◽  
Vol 106 (4) ◽  
pp. 336-339 ◽  
Author(s):  
TONG MING LIN ◽  
CZAU SIUNG YANG ◽  
JWO FARN CHIOU ◽  
SHIH MIEN TU ◽  
TING YAO CHEN ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Epstein Barr Virus ◽  
Early Antigen ◽  
Virus Capsid ◽  
Barr Virus ◽  
Comparison Groups ◽  
Epstein Barr ◽  
Virus Capsid Antigen

Studies of Epstein-Barr Virus Antigens Using Immunoperoxidase and Immunofluorescence Techniques

1975 ◽  
Vol 33 ◽  
pp. 342-343
Author(s):  
R. Stephens ◽  
K. Traul ◽  
D. Woolf ◽  
P. Gaudreau
Keyword(s):  
Electron Microscopy ◽  
Nasopharyngeal Carcinoma ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
If Technique ◽  
Infected Cells ◽  
Virus Antigens ◽  
Epstein Barr ◽  
Virus Capsid Antigen ◽  
Antigen Reactivity

A number of antigens have been found associated with persistent EBV infections of lymphoblastoid cells. Identification and localization of these antigens were principally by immunofluorescence (IF) techniques using sera from patients with nasopharyngeal carcinoma (NPC), Burkitt lymphoma (BL), and infectious mononucleosis (IM). Our study was mainly with three of the EBV related antigens, a) virus capsid antigen (VCA), b) membrane antigen (MA), and c) early antigens (EA) using immunoperoxidase (IP) techniques with electron microscopy (EM) to elucidate the sites of reactivity with EBV and EBV infected cells.Prior to labeling with horseradish peroxidase (HRP), sera from NPC, IM, and BL cases were characterized for various reactivities by the indirect IF technique. Modifications of the direct IP procedure described by Shabo and the indirect IP procedure of Leduc were made to enhance penetration of the cells and preservation of antigen reactivity.

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