scholarly journals Elevated expression of G3BP1 associates with YB1 and p‐AKT and predicts poor prognosis in nonsmall cell lung cancer patients after surgical resection

2019 ◽  
Vol 8 (16) ◽  
pp. 6894-6903 ◽  
Author(s):  
Hongmei Zheng ◽  
Yuting Zhan ◽  
Yuting Zhang ◽  
Sile Liu ◽  
Junmi Lu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Patients ◽  
Surgical Resection ◽  
Cell Lung Cancer ◽  
Poor Prognosis ◽  
Nonsmall Cell Lung Cancer ◽  
Lung Cancer Patients ◽  
Elevated Expression

scholarly journals Time-Dependent Changes of Plasma Concentrations of Angiopoietins, Vascular Endothelial Growth Factor, and Soluble Forms of Their Receptors in Nonsmall Cell Lung Cancer Patients Following Surgical Resection

ISRN Oncology ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Ewa Kopczynska ◽  
Maciej Dancewicz ◽  
Janusz Kowalewski ◽  
Roman Makarewicz ◽  
Hanna Kardymowicz ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Patients ◽  
Surgical Resection ◽  
Cell Lung Cancer ◽  
Early Stage ◽  
Plasma Concentrations ◽  
Nonsmall Cell Lung Cancer ◽  
Lung Cancer Patients ◽  
Endothelial Growth Factor ◽  
The Impact

Even when patients with nonsmall cell lung cancer undergo surgical resection at an early stage, recurrent disease often impairs the clinical outcome. There are numerous causes potentially responsible for a relapse of the disease, one of them being extensive angiogenesis. The balance of at least two systems, VEGF VEGFR and Ang Tie, regulates vessel formation. The aim of this study was to determine the impact of surgery on the plasma levels of the main angiogenic factors during the first month after surgery in nonsmall cell lung cancer patients. The study group consisted of 37 patients with stage I nonsmall cell lung cancer. Plasma concentrations of Ang1, Ang2, sTie2, VEGF, and sVEGF R1 were evaluated by ELISA three times: before surgical resection and on postoperative days 7 and 30. The median of Ang2 and VEGF concentrations increased on postoperative day 7 and decreased on day 30. On the other hand, the concentration of sTie2 decreased on the 7th day after resection and did not change statistically later on. The concentrations of Ang1 and sVEGF R1 did not change after the surgery. Lung cancer resection results in proangiogenic plasma protein changes that may stimulate tumor recurrences and metastases after early resection.

scholarly journals Rapid intracranial response to osimertinib, without radiotherapy, in nonsmall cell lung cancer patients harboring the EGFR T790M mutation

Medicine ◽  
2017 ◽  
Vol 96 (6) ◽  
pp. e6087 ◽  
Author(s):  
Taro Koba ◽  
Takashi Kijima ◽  
Takayuki Takimoto ◽  
Haruhiko Hirata ◽  
Yujiro Naito ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Patients ◽  
Cell Lung Cancer ◽  
Nonsmall Cell Lung Cancer ◽  
T790m Mutation ◽  
Lung Cancer Patients ◽  
Egfr T790m

scholarly journals Glyceraldehyde-3-phosphate dehydrogenase gene over expression correlates with poor prognosis in non small cell lung cancer patients

2013 ◽  
Vol 12 (1) ◽  
pp. 97 ◽  
Author(s):  
Roberto Puzone ◽  
Graziana Savarino ◽  
Sandra Salvi ◽  
Maria Dal Bello ◽  
Giulia Barletta ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cancer Patients ◽  
Cell Lung Cancer ◽  
Poor Prognosis ◽  
Small Cell ◽  
Small Cell Lung ◽  
Lung Cancer Patients ◽  
Over Expression ◽  
Dehydrogenase Gene
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