scholarly journals Genetic risk association of CDKN1A and RET gene SNPs with medullary thyroid carcinoma: Results from the largest MTC cohort and meta‐analysis

2019 ◽  
Vol 8 (13) ◽  
pp. 6151-6161
Author(s):  
Vasudha Mishra ◽  
Pradnya Kowtal ◽  
Pallavi Rane ◽  
Rajiv Sarin
Keyword(s):  
Thyroid Carcinoma ◽  
Medullary Thyroid Carcinoma ◽  
Genetic Risk ◽  
Meta Analysis ◽  
Medullary Thyroid ◽  
Ret Gene ◽  
Risk Association

Analysis of alternative mechanisms for RET gene activation in hereditary and sporadic Medullary Thyroid Carcinoma

2010 ◽  
Vol 203 (1) ◽  
pp. 50
Author(s):  
Ciampi Raffaele ◽  
Romei Cristina ◽  
Vivaldi Agnese ◽  
Cosci Barbara ◽  
Tacito Alessia ◽  
...  
Keyword(s):  
Thyroid Carcinoma ◽  
Medullary Thyroid Carcinoma ◽  
Gene Activation ◽  
Sporadic Medullary Thyroid Carcinoma ◽  
Medullary Thyroid ◽  
Ret Gene

scholarly journals Retroposed copies of RET gene: a somatically acquired event in medullary thyroid carcinoma

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Larissa V. Bim ◽  
Fábio C. P. Navarro ◽  
Flávia O. F. Valente ◽  
José V. Lima-Junior ◽  
Rosana Delcelo ◽  
...  
Keyword(s):  
Thyroid Carcinoma ◽  
Medullary Thyroid Carcinoma ◽  
Medullary Thyroid ◽  
Ret Gene

The involvement of the RET variant G691S in medullary thyroid carcinoma enlightened by a meta-analysis study

2012 ◽  
Vol 132 (12) ◽  
pp. 2808-2819 ◽  
Author(s):  
Francesca Lantieri ◽  
Francesco Caroli ◽  
Isabella Ceccherini ◽  
Paola Griseri
Keyword(s):  
Thyroid Carcinoma ◽  
Medullary Thyroid Carcinoma ◽  
Meta Analysis ◽  
Medullary Thyroid ◽  
Analysis Study

scholarly journals Detection rate of FNA cytology in medullary thyroid carcinoma: a meta-analysis

2014 ◽  
Vol 82 (2) ◽  
pp. 280-285 ◽  
Author(s):  
Pierpaolo Trimboli ◽  
Giorgio Treglia ◽  
Leo Guidobaldi ◽  
Francesco Romanelli ◽  
Giuseppe Nigri ◽  
...  
Keyword(s):  
Thyroid Carcinoma ◽  
Medullary Thyroid Carcinoma ◽  
Detection Rate ◽  
Meta Analysis ◽  
Medullary Thyroid

scholarly journals Calcitonin-secreting neuroendocrine neoplasms of the lung: a systematic review and narrative synthesis

2021 ◽  
Vol 10 (4) ◽  
pp. 447-461
Author(s):  
David C Llewellyn ◽  
Rajaventhan Srirajaskanthan ◽  
Royce P Vincent ◽  
Catherine Guy ◽  
Eftychia E Drakou ◽  
...  
Keyword(s):  
Systematic Review ◽  
Thyroid Carcinoma ◽  
Medullary Thyroid Carcinoma ◽  
Meta Analysis ◽  
A Priori ◽  
Neuroendocrine Neoplasm ◽  
Neuroendocrine Neoplasms ◽  
Cochrane Central Register ◽  
Medullary Thyroid ◽  
Stimulation Tests

Calcitonin-secreting neuroendocrine neoplasms of the lung are rare, with few cases reported in the literature. Differentiating between medullary thyroid carcinoma and an ectopic source of calcitonin secretion can represent a complex diagnostic conundrum for managing physicians, with cases of unnecessary thyroidectomy reported in the literature. This manuscript reports a case of ectopic hypercalcitonaemia from a metastatic neuroendocrine neoplasm of the lung with concurrent thyroid pathology and summarises the results of a systematic review of the literature. Medical Literature Analysis and Retrieval System Online, Excerpta Medica, Cochrane Central Register of Controlled Trials, ClinicalTrials.gov and SCOPUS databases were systematically and critically appraised for all peer reviewed manuscripts that suitably fulfilled the inclusion criteria established a priori. The protocol for this systematic review was developed according to the Preferred Reporting Items for Systematic review and Meta-Analysis Protocols, and followed methods outlined in The Cochrane Handbook for Systematic Reviews of Interventions. This systematic review is registered with PROSPERO. It is vital to consider diagnoses other than medullary thyroid carcinoma when presented with a patient with raised calcitonin, as it is not pathognomonic of medullary thyroid carcinoma. Lung neuroendocrine neoplasms can appear similar to medullary thyroid carcinoma histologically, they can secrete calcitonin and metastasize to the thyroid. Patients with medullary thyroid carcinoma may show stimulated calcitonin values over two or more times above the basal values, whereas calcitonin-secreting neuroendocrine neoplasms may or may not show response to stimulation tests. The present review summarises existing evidence from cases of ectopic hypercalcitonaemia to lung neuroendocrine neoplasms.

scholarly journals Analysis of Newly Identified and Rare Synonymous Genetic Variants in the RET Gene in Patients with Medullary Thyroid Carcinoma in Polish Population

2017 ◽  
Vol 28 (3) ◽  
pp. 198-206
Author(s):  
Maria Sromek ◽  
Małgorzata Czetwertyńska ◽  
Magdalena Tarasińska ◽  
Aneta Janiec-Jankowska ◽  
Renata Zub ◽  
...  
Keyword(s):  
Thyroid Carcinoma ◽  
Medullary Thyroid Carcinoma ◽  
Genetic Variants ◽  
Polish Population ◽  
Medullary Thyroid ◽  
Ret Gene
Sign in / Sign up

Export Citation Format

Share Document