scholarly journals Validation of the preoperative controlling nutritional status score as an independent predictor in a large Chinese cohort of patients with upper tract urothelial carcinoma

2018 ◽  
Vol 7 (12) ◽  
pp. 6112-6123 ◽  
Author(s):  
Hang Xu ◽  
Ping Tan ◽  
Xi Jin ◽  
Jianzhong Ai ◽  
Tianhai Lin ◽  
...  
Keyword(s):  
Nutritional Status ◽  
Urothelial Carcinoma ◽  
Independent Predictor ◽  
Upper Tract Urothelial Carcinoma ◽  
Upper Tract ◽  
Status Score ◽  
Chinese Cohort

The prognostic value of the controlling nutritional status (CONUT) score on patients undergoing nephrectomy for upper tract urothelial carcinoma or renal cell carcinoma: a systematic review and meta-analysis

2021 ◽  
pp. 1-20
Author(s):  
Junhao Chen ◽  
Dehong Cao ◽  
Zhufeng Peng ◽  
Pan Song ◽  
Zhenghuan Liu ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Nutritional Status ◽  
Urothelial Carcinoma ◽  
Cell Carcinoma ◽  
Subgroup Analysis ◽  
Renal Cell ◽  
Prognostic Value ◽  
Upper Tract Urothelial Carcinoma ◽  
Upper Tract ◽  
Conut Score

Abstract Background & aims: In recent years, the controlling nutritional status (CONUT) score has increasingly became an effective indicator associated with tumor prognosis. This study was conducted to synthesise data on the prognostic value of CONUT score on patients with upper tract urothelial carcinoma (UTUC) or renal cell carcinoma (RCC) undergoing nephrectomy. Methods: We designed and performed a systematic analysis of studies that verified the correlation between preoperative CONUT score and prognosis for UTUC and RCC using PubMed, Web of Science and Embase. The conclusion was clarified by pooled hazard ratios (HR) and 95% confidence intervals (95% CI). Subgroup analysis were further conducted in accordance with different primary tumor. Results: Six studies involving 3529 patients were included in this evidence synthesis, which revealed that the CONUT score had a potential role to predict the survival of UTUC and RCC patients accepting surgery. Pooled analysis showed that the overall survival (OS, HR 2.32, p<0.0001), cancer-special survival (CSS, HR 2.68, p<0.0001) and disease-free survival (DFS, HR 1.62, p<0.00001) were inferior in the high CONUT score group when compared with low score group. Subgroup analysis revealed that this result was in line with UTUC (OS: HR 1.86, P=0.02; CSS: HR 2.24, P=0.01; DFS: HR 1.54, P<0.00001) and RCC (OS: HR 3.05, P<0.00001; CSS: HR 3.47, P<0.00001; DFS: HR 2.21, P=0.0005) patients respectively. Conclusion: The CONUT score is a valuable preoperative index to predict the survival of patients with UTUC or RCC undergoing nephrectomy.

Prospective Analysis of Ki-67 as an Independent Predictor of Oncologic Outcomes in Patients with High Grade Upper Tract Urothelial Carcinoma

2014 ◽  
Vol 191 (1) ◽  
pp. 28-34 ◽  
Author(s):  
Laura-Maria Krabbe ◽  
Aditya Bagrodia ◽  
Yair Lotan ◽  
Bishoy A. Gayed ◽  
Oussama M. Darwish ◽  
...  
Keyword(s):  
Urothelial Carcinoma ◽  
Independent Predictor ◽  
Upper Tract Urothelial Carcinoma ◽  
Oncologic Outcomes ◽  
Prospective Analysis ◽  
High Grade ◽  
Ki 67 ◽  
Upper Tract
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