scholarly journals Dysregulated circular RNAs in medulloblastoma regulate proliferation and growth of tumor cells via host genes

2018 ◽  
Vol 7 (12) ◽  
pp. 6147-6157 ◽  
Author(s):  
Tao Lv ◽  
Yi-Feng Miao ◽  
Ke Jin ◽  
Shuo Han ◽  
Tian-Qi Xu ◽  
...  
1961 ◽  
Vol 236 (2) ◽  
pp. 285-288
Author(s):  
John Papaconstantinou ◽  
Sidney P. Colowick
Keyword(s):  

1965 ◽  
Vol 240 (7) ◽  
pp. 2791-2796
Author(s):  
Edward B. Goldberg ◽  
Harold M. Nitowsky ◽  
Sidney P. Colowick
Keyword(s):  

1983 ◽  
Vol 11 (01n04) ◽  
pp. 69-73 ◽  
Author(s):  
Y.M. Choy ◽  
T.T. Kwok ◽  
K.P. Fung ◽  
C.Y. Lee

A number of food materials or drugs have been screened for the effect on the growth and development of transplantable Ehrlich ascites tumor cells. Growth of tumor-bearing mice was significantly inhibited by feeding garlic as well as some amino acids. These materials significantly reduced the total number of free tumor cells growing in the peritoneal cavity of mice and prolonged significantly the length of time for 50% death of tumor-bearing mice.


2012 ◽  
Vol 05 (03) ◽  
pp. 1260017 ◽  
Author(s):  
LING CHEN ◽  
WANBIAO MA

In this paper, based on some biological meanings and a model which was proposed by Lefever and Garay (1978), a nonlinear delay model describing the growth of tumor cells under immune surveillance against cancer is given. Then, boundedness of the solutions, local stability of the equilibria and Hopf bifurcation of the model are discussed in details. The existence of periodic solutions explains the restrictive interactions between immune surveillance and the growth of the tumor cells.


1998 ◽  
Vol 101 (7) ◽  
pp. 1301-1309 ◽  
Author(s):  
Y Zhang ◽  
H Weiler-Guettler ◽  
J Chen ◽  
O Wilhelm ◽  
Y Deng ◽  
...  

Biomolecules ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 1040 ◽  
Author(s):  
Milad Ashrafizadeh ◽  
Hui Li Ang ◽  
Ebrahim Rahmani Moghadam ◽  
Shima Mohammadi ◽  
Vahideh Zarrin ◽  
...  

Molecular signaling pathways involved in cancer have been intensively studied due to their crucial role in cancer cell growth and dissemination. Among them, zinc finger E-box binding homeobox-1 (ZEB1) and -2 (ZEB2) are molecules that play vital roles in signaling pathways to ensure the survival of tumor cells, particularly through enhancing cell proliferation, promoting cell migration and invasion, and triggering drug resistance. Importantly, ZEB proteins are regulated by microRNAs (miRs). In this review, we demonstrate the impact that miRs have on cancer therapy, through their targeting of ZEB proteins. MiRs are able to act as onco-suppressor factors and inhibit the malignancy of tumor cells through ZEB1/2 down-regulation. This can lead to an inhibition of epithelial-mesenchymal transition (EMT) mechanism, therefore reducing metastasis. Additionally, miRs are able to inhibit ZEB1/2-mediated drug resistance and immunosuppression. Additionally, we explore the upstream modulators of miRs such as long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs), as these regulators can influence the inhibitory effect of miRs on ZEB proteins and cancer progression.


Author(s):  
Jiguang Ma ◽  
Mengwen Xue ◽  
Simei Zhang ◽  
Liang Cheng ◽  
Weikun Qian ◽  
...  

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