scholarly journals Expression of FAP, ADAM12, WISP1, and SOX11 is heterogeneous in aggressive fibromatosis and spatially relates to the histologic features of tumor activity

2013 ◽  
Vol 3 (1) ◽  
pp. 81-90 ◽  
Author(s):  
Benjamin S. Misemer ◽  
Amy P. N. Skubitz ◽  
J. Carlos Manivel ◽  
Stephen C. Schmechel ◽  
Edward Y. Cheng ◽  
...  
Keyword(s):  
Aggressive Fibromatosis

scholarly journals Clinicopathological features and differential diagnosis of gastrofibromatosis-like undifferentiated carcinoma

2020 ◽  
Vol 48 (12) ◽  
pp. 030006052097446
Author(s):  
Zhishang Zhang ◽  
Guang Zhao ◽  
Bo Jiang ◽  
Baohui Li ◽  
Yangkun Wang
Keyword(s):  
Differential Diagnosis ◽  
Gene Amplification ◽  
Smooth Muscle Actin ◽  
Growth Factor Receptor ◽  
Aggressive Fibromatosis ◽  
Undifferentiated Carcinoma ◽  
Clinicopathological Features ◽  
Gastric Body ◽  
Her2 Gene ◽  
Her2 Gene Amplification

Objective To study the clinicopathological features and differential diagnosis of gastrofibromatosis-like undifferentiated carcinoma (GFLUC). Methods Three patients with GFLUC underwent histological and immunophenotypic analyses and fluorescence in situ hybridization to detect human epidermal growth factor receptor ( HER2) gene amplification. Results Among the three patients (2 male [36 and 44 years old], 1 female [58 years old]), two had lesions in the gastric body and one had lesions in the gastric antrum. Histological analysis revealed mixtures of aggressive fibromatosis and undifferentiated carcinoma in all three cases. Highly invasive fibromatous tissue, consisting of fibroblasts, proliferating myofibroblasts, and collagenous fibrous tissues, accounted for >90% of the tumor, with undifferentiated cancerous tissue accounting for <10% scattered in the gaps within the invasive fibromatous tissue, with no glandular ducts or nests. Immunophenotypic analysis showed that the undifferentiated cancerous cells were positive for pan-cytokeratin, CDX2, villin, and p53, while the cytoplasm of invasive fibromatous cells was positive for vimentin, β-catenin, and smooth muscle actin. No HER2 gene amplification was detected. Conclusions Unlike other gastric carcinomas, GFLUC shows specific histological, biological, and immunophenotypic characteristics.

Diagnostic Approach of Juvenile Aggressive Fibromatosis of Mandible

2021 ◽  
Author(s):  
Shamala Sivanandham ◽  
Devika Kollara Vidhyadharan ◽  
Durairaj Duraisamy ◽  
Arvind Babu Rajendra Santosh
Keyword(s):  
Aggressive Fibromatosis ◽  
Diagnostic Approach

Aggressive Fibromatosis of the Larynx: Report of a New Case in an Adult Patient and Review of the Literature

2001 ◽  
Vol 197 (1) ◽  
pp. 51-55 ◽  
Author(s):  
M. Mirra ◽  
S. Calò ◽  
T. Salviato ◽  
D. Della Libera ◽  
G. Falconieri
Keyword(s):  
Adult Patient ◽  
Aggressive Fibromatosis ◽  
Review Of The Literature

Radiotherapy for local control of aggressive fibromatosis

1996 ◽  
Vol 36 (2) ◽  
pp. 325-328 ◽  
Author(s):  
Sachin S. Kamath ◽  
James T. Parsons ◽  
Robert B. Marcus ◽  
Robert A. Zlotecki ◽  
Mark T. Scarborough
Keyword(s):  
Local Control ◽  
Aggressive Fibromatosis

Sporadic Retroperitoneal Aggressive Fibromatosis: Report of a Case

2009 ◽  
Vol 135 (01) ◽  
pp. 79-82 ◽  
Author(s):  
G. Ghidirim ◽  
I. Mishin ◽  
I. Gagauz ◽  
M. Vozian ◽  
G. Zastavnitsky ◽  
...  
Keyword(s):  
Aggressive Fibromatosis
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