scholarly journals Tissue-based quantitative proteomics to screen and identify the potential biomarkers for early recurrence/metastasis of esophageal squamous cell carcinoma

2018 ◽  
Vol 7 (6) ◽  
pp. 2504-2517 ◽  
Author(s):  
Xu-Wei Cai ◽  
Wei-Wei Yu ◽  
Wen Yu ◽  
Qin Zhang ◽  
Wen Feng ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Quantitative Proteomics ◽  
Early Recurrence ◽  
Potential Biomarkers

scholarly journals Early Recurrence and Cancer Death After Trimodal Therapy for Esophageal Squamous Cell Carcinoma

2019 ◽  
Vol 39 (3) ◽  
pp. 1433-1440 ◽  
Author(s):  
YOICHI HAMAI ◽  
MANABU EMI ◽  
YUTA IBUKI ◽  
YUJI MURAKAMI ◽  
IKUNO NISHIBUCHI ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Recurrence ◽  
Cancer Death ◽  
Trimodal Therapy

Predictive factors for early recurrence in patients with esophageal squamous cell carcinoma after curative esophagectomy

Esophagus ◽  
2012 ◽  
Vol 9 (1) ◽  
pp. 17-24
Author(s):  
Hiroki Shimizu ◽  
Atsushi Shiozaki ◽  
Hitoshi Fujiwara ◽  
Shuhei Komatsu ◽  
Daisuke Ichikawa ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Predictive Factors ◽  
Early Recurrence ◽  
Curative Esophagectomy

New potential biomarkers in the diagnosis of esophageal squamous cell carcinoma

Biomarkers ◽  
2009 ◽  
Vol 14 (5) ◽  
pp. 340-346 ◽  
Author(s):  
Shu-Yong Xu ◽  
Zan Liu ◽  
Wen-Jing Ma ◽  
Ilyar Sheyhidin ◽  
Shu-Tao Zheng ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Potential Biomarkers

scholarly journals Loss of CADM1/TSLC1 Expression Is Associated with Poor Clinical Outcome in Patients with Esophageal Squamous Cell Carcinoma

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
De Zeng ◽  
Xiao Wu ◽  
Jin Zheng ◽  
Yixuan Zhuang ◽  
Jiongyu Chen ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cox Regression ◽  
Histological Grade ◽  
Disease Free Survival ◽  
Early Recurrence ◽  
Clinicopathological Parameters ◽  
Survival Duration

Aims. We sought to determine the relationship between CADM1/TSLC1 expression and clinicopathological characteristics in patients with esophageal squamous cell carcinoma (ESCC) and the correlation with survival.Materials and Methods. Two hundred and ninety-three ESCC tissues and paired adjacent normal esophageal tissues were immunohistochemically assessed in this study. The association of CADM1/TSLC1 with clinicopathological parameters, as well as disease-free survival (DFS) and overall survival (OS), was determined based on the Kaplan-Meier method and Cox regression models.Results. CADM1/TSLC1 was detected in 236 (80.5%) tumor tissues and 19 (8.0%) paired adjacent normal esophageal tissues. Decreased CADM1/TSLC1 expression was correlated with more advanced histological grade. CADM1/TSLC1 negative tumors were more frequently observed in male cases than in female cases. DFS and OS in the CADM1/TSLC1 negative group were significantly shorter than those in the positive group, particularly in male patients with ESCC.Conclusion. Loss or reduction of CADM1/TSLC1 expression is associated with more advanced histological grade and predicts early recurrence and short survival duration. Thus, loss of CADM1/TSLC1 could be a prognostic factor that can be used to assess the risk of recurrence and survival.

Sign in / Sign up

Export Citation Format

Share Document