scholarly journals Assessment of the American Joint Commission on Cancer 8th Edition Staging System for Patients with Pancreatic Neuroendocrine Tumors: A Surveillance, Epidemiology, and End Results analysis

2018 ◽  
Vol 7 (3) ◽  
pp. 626-634 ◽  
Author(s):  
Xiaogang Li ◽  
Shanmiao Gou ◽  
Zhiqiang Liu ◽  
Zeng Ye ◽  
Chunyou Wang
Keyword(s):  
Neuroendocrine Tumors ◽  
Staging System ◽  
Joint Commission ◽  
Pancreatic Neuroendocrine Tumors ◽  
8Th Edition ◽  
End Results

Application of the Pancreatic Adenocarcinoma Staging System to Pancreatic Neuroendocrine Tumors

2007 ◽  
Vol 205 (4) ◽  
pp. 558-563 ◽  
Author(s):  
Karl Y. Bilimoria ◽  
David J. Bentrem ◽  
Ryan P. Merkow ◽  
James S. Tomlinson ◽  
Andrew K. Stewart ◽  
...  
Keyword(s):  
Pancreatic Adenocarcinoma ◽  
Neuroendocrine Tumors ◽  
Staging System ◽  
Pancreatic Neuroendocrine Tumors

scholarly journals Prognostic Validity of the American Joint Committee on Cancer Eighth Edition Staging System for Well-Differentiated Pancreatic Neuroendocrine Tumors: A Retrospective Multinational Multicenter Study

2020 ◽  
Author(s):  
Hebin Wang ◽  
Ding Ding ◽  
Tingting Qin ◽  
Jun Liu ◽  
Hang Zhang ◽  
...  
Keyword(s):  
Neuroendocrine Tumors ◽  
Staging System ◽  
Tnm Staging ◽  
Stage I ◽  
Pancreatic Neuroendocrine Tumors ◽  
American Joint Committee ◽  
Staging Systems ◽  
Significant Difference ◽  
Well Differentiated ◽  
Eighth Edition

Abstract Background:There is no widely-accepted staging system for pancreatic neuroendocrine tumors (pNETs). The aim of this study was to validate the American Joint Committee on Cancer (AJCC) 8th edition staging system for well-differentiated (G1/G2) pNETs.Methods:A multicenter dataset (n=1086) was used to evaluate the application of the AJCC 7th and 8th, the European Neuroendocrine Tumor Society (ENETS), and the modified ENETS (mENETS) staging systems for well-differentiated pNETs.Results:The proportion of patients with stage III tumors was extremely low (1.1%) according to the AJCC 7th staging system. For the ENETS staging system, patients with stage IIIA disease had worse estimated mean survival than patients with stage IIIB disease (78.9 vs. 107.3 months). When comparing with patients in stage I, the AJCC 7th, ENETS, and mENETS staging systems showed good performance in discriminating between stages; however, there was no significant difference in some stages when the reference was defined as the earlier stage. When the reference was defined as stage I or the earlier stage, there was a significant inter-stage difference in the AJCC 8th staging system.Conclusions:The AJCC 8th staging system is more suitable for pNETs than other TNM staging systems and may be adopted in clinical practice.

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