scholarly journals Tumor organoids: synergistic applications, current challenges, and future prospects in cancer therapy

2021 ◽  
Author(s):  
Jingjing Qu ◽  
Farhin Shaheed Kalyani ◽  
Li Liu ◽  
Tianli Cheng ◽  
Lijun Chen
Author(s):  
Muddukrishnaiah K.

Due to drug resistance, lack of cancer cell selectivity, and solubility, conventional cancer treatments lose their therapeutic uses, and as such, new therapeutic agents need to be developed. Nanomaterials and peptides are increasingly being used in the fields of cancer diagnosis, biomarker discovery due to their therapeutic values and novel way of targeting and curing the disease. Synergism among the peptide-conjugated nanoparticles is an exhilarating group of materials, not only sharing the benefits of conventional nanomedicine, but also possessing the unique properties of excellent biocompatibility, biodegradability, versatile sensitivity, specific biological purpose, and synthetic feasibility. These virtues inspired by the scientists and have taken advantage in the peptide-conjugated nano drugs for the accurate delivery of drugs reliably to the site of the lesion. This chapter offers a summary of emerging technologies that have recently been developed in the broad field of peptide-conjugated nanoparticles and offers guidance for targeted drug delivery and cancer therapy.


2019 ◽  
Vol 10 (2) ◽  
pp. 113-132 ◽  
Author(s):  
Gizem Bor ◽  
Intan Diana Mat Azmi ◽  
Anan Yaghmur

Author(s):  
Kah Min Yap ◽  
Mahendran Sekar ◽  
Yuan Seng Wu ◽  
Siew Hua Gan ◽  
Nur Najihah Izzati Mat Rani ◽  
...  

2007 ◽  
Vol 13 (6) ◽  
pp. 223-230 ◽  
Author(s):  
Dan G. Duda ◽  
Tracy T. Batchelor ◽  
Christopher G. Willett ◽  
Rakesh K. Jain

2019 ◽  
Vol 3 (2) ◽  
pp. 76
Author(s):  
Wei Boon Yap ◽  
Shaktypreya Nadarajah ◽  
Nadiah Shidik ◽  
Noorjahan Banu Mohammed Alitheen

Cancer immunotherapy using cytokines has been sought as an alternative therapeutic approach for treating cancers. Besides remarkable immunoregulatory properties, interleukin (IL)-27 has recently been shown to possess promising anticancer functions; hence, its potential roles in cancer immunotherapy. Although proven to be effective against cancer cell growth and angiogenesis, given its dual immune-regulating functions (pro-inflammatory and anti-inflammatory), the use of IL-27 as a cancer immunotherapeutic cytokine could possibly be a two-edged sword without meticulous and thorough research. This mini-review mainly discusses the functions and future prospects of IL-27 as an effective anticancer cytokine. Hopefully, it imparts useful insights into the potential applications of IL-27 in cancer immunotherapy


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