Intramuscular innervation of the lateral rectus muscle evaluated using sihler's staining technique: Potential application to strabismus surgery

2020 ◽  
Vol 33 (4) ◽  
pp. 585-591 ◽  
Author(s):  
Robert Haładaj ◽  
Grzegorz Wysiadecki ◽  
R. Shane Tubbs
Keyword(s):  
Potential Application ◽  
Rectus Muscle ◽  
Staining Technique ◽  
Strabismus Surgery ◽  
Lateral Rectus ◽  
Lateral Rectus Muscle ◽  
Sihler’S Staining

Worldwide outcomes of nasal transposition of the split lateral rectus muscle for strabismus associated with 3rd-nerve palsy

2021 ◽  
pp. bjophthalmol-2021-319667
Author(s):  
Ankoor S Shah ◽  
Mary-Magdalene Ugo Dodd ◽  
Birsen Gokyigit ◽  
Birgit Lorenz ◽  
Erick Laurent ◽  
...  
Keyword(s):  
Success Rate ◽  
Nerve Palsy ◽  
Rectus Muscle ◽  
Strabismus Surgery ◽  
Lateral Rectus ◽  
Oblique Muscle ◽  
Primary Position ◽  
Lateral Rectus Muscle ◽  
Muscle Insertion ◽  
Contralateral Eye

Background/aimsTo determine success rate and complications associated with nasal transposition of the split lateral rectus muscle (NTSLR) for treating strabismus from 3rd-nerve palsy.MethodsAn international, multicentre, registry of patients with unilateral 3rd-nerve palsy treated with NTSLR was created. Patients with concurrent surgery on the contralateral eye were excluded. Primary outcome was horizontal alignment within 15 prism dioptres (PD) of orthotropia. Incidence of technical difficulties and vision-threatening complications by 6 months post-procedure were reported.ResultsNinety-eight patients met inclusion criteria. Median age was 33.5 years (IQR 10.75–46). Aetiologies included congenital (31%), neoplastic (16%) and traumatic (15%). Twenty-five per cent of patients had prior ipsilateral strabismus surgery. Median exotropia decreased from 70PD preoperatively (IQR 50–90) to 1PD postoperatively (IQR 0–15.5), with a success rate of 69%. Performing concurrent superior oblique muscle tenotomy (SOT) was independently associated with success (p=0.001). Technical challenges occurred in 30% of cases, independently associated with a history of ipsilateral strabismus surgery (p=0.01). Eleven per cent of patients had vision-threatening complications, independently associated with more posterior placement of the split lateral rectus (LR) muscle (p<0.001), and most commonly transient serous choroidal effusion. Surgical placement of the split LR muscle within 4.25 mm of the medial rectus (MR) muscle insertion reduced this risk.ConclusionNTSLR significantly improved primary position alignment altered by 3rd-nerve palsy. Concurrent SOT and placement of the split LR muscle ≤4.25 mm posterior to the MR muscle insertion optimised outcomes. NTSLR proved technically challenging when prior ipsilateral strabismus surgery had been performed.

scholarly journals Lateral rectus muscle differentiation potential in paralytic esotropia patients

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Qing Xia ◽  
Xiangtian Ling ◽  
Zhonghao Wang ◽  
Tao Shen ◽  
Minghao Chen ◽  
...  
Keyword(s):  
Gene Expression ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Rectus Muscle ◽  
Lateral Rectus ◽  
Control Group ◽  
Differentiation Potential ◽  
Partial Restoration ◽  
Reverse Transcription Pcr ◽  
Lateral Rectus Muscle

Abstract Purpose and background Recently, we found that maximal medial rectus recession and lateral rectus resection in patients with complete lateral rectus paralysis resulted in a partial restoration of abduction. In an attempt to understand some of the mechanisms involved with this effect we examined gene expression profiles of lateral recti from these patients, with our focus being directed to genes related to myogenesis. Materials and methods Lateral recti resected from patients with complete lateral rectus paralysis and those from concomitant esotropia (controls) were collected. Differences in gene expression profiles between these two groups were examined using microarray analysis and quantitative Reverse-transcription PCR (qRT-PCR). Results A total of 3056 differentially expressed genes (DEGs) were identified between these two groups. Within the paralytic esotropia group, 2081 genes were up-regulated and 975 down-regulated. The results of RT-PCR revealed that PAX7, MYOG, PITX1, SIX1 and SIX4 showed higher levels of expression, while that of MYOD a lower level of expression within the paralytic esotropia group as compared with that in the control group (p < 0.05). Conclusion The decreased expression of MYOD in the paralytic esotropia group suggested that extraocular muscle satellite cell (EOMSCs) differentiation processes were inhibited. Whereas the high expression levels of PAX7, SIX1/4 and MYOG, suggested that the EOMSCs were showing an effective potential for differentiation. The stimulation resulting from muscle surgery may induce EOMSCs to differentiate and thus restore abduction function.

Behavior of cat abducens motoneurons following the injection of toxic ricin into the lateral rectus muscle

1991 ◽  
Vol 544 (2) ◽  
pp. 260-268 ◽  
Author(s):  
R.R. de la Cruz ◽  
R. Baker ◽  
J.M. Delgado-García
Keyword(s):  
Rectus Muscle ◽  
Lateral Rectus ◽  
Lateral Rectus Muscle

Lateral Rectus Muscle Palsy, Facial Numbness and Ataxia as the Initial Manifestation of Multiple Sclerosis

2008 ◽  
Vol 100 (5) ◽  
pp. 572-574 ◽  
Author(s):  
John P. Mitchell ◽  
Joshua Beer ◽  
Asha Yancy ◽  
Leslie A. Saint-Louis ◽  
Daniel F. Rosberger
Keyword(s):  
Multiple Sclerosis ◽  
Rectus Muscle ◽  
Lateral Rectus ◽  
Initial Manifestation ◽  
Lateral Rectus Muscle ◽  
Facial Numbness

Intramuscular Distribution of the Abducens Nerve in the Lateral Rectus Muscle for the Management of Strabismus

2018 ◽  
Vol 43 (6) ◽  
pp. 689-695 ◽  
Author(s):  
Hyun Jin Shin ◽  
Shin-Hyo Lee ◽  
Kang-Jae Shin ◽  
Ki-Seok Koh ◽  
Wu-Chul Song
Keyword(s):  
Rectus Muscle ◽  
Abducens Nerve ◽  
Lateral Rectus ◽  
Lateral Rectus Muscle
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