Microsurgical anatomy of the posterior median septum of the human spinal cord

2014 ◽  
Vol 28 (1) ◽  
pp. 45-51 ◽  
Author(s):  
Erhan Turkoglu ◽  
Hayri Kertmen ◽  
Kutluay Uluc ◽  
Erinc Akture ◽  
Bora Gurer ◽  
...  
Author(s):  
V. Kriho ◽  
H.-Y. Yang ◽  
C.-M. Lue ◽  
N. Lieska ◽  
G. D. Pappas

Radial glia have been classically defined as those early glial cells that radially span their thin processes from the ventricular to the pial surfaces in the developing central nervous system. These radial glia constitute a transient cell population, disappearing, for the most part, by the end of the period of neuronal migration. Traditionally, it has been difficult to definitively identify these cells because the principal criteria available were morphologic only.Using immunofluorescence microscopy, we have previously defined a phenotype for radial glia in rat spinal cord based upon the sequential expression of vimentin, glial fibrillary acidic protein and an intermediate filament-associated protein, IFAP-70/280kD. We report here the application of another intermediate filament-associated protein, IFAP-300kD, originally identified in BHK-21 cells, to the immunofluorescence study of radial glia in the developing rat spinal cord.Results showed that IFAP-300kD appeared very early in rat spinal cord development. In fact by embryonic day 13, IFAP-300kD immunoreactivity was already at its peak and was observed in most of the radial glia which span the spinal cord from the ventricular to the subpial surfaces (Fig. 1). Interestingly, from this time, IFAP-300kD immunoreactivity diminished rapidly in a dorsal to ventral manner, so that by embryonic day 16 it was detectable only in the maturing macroglial cells in the marginal zone of the spinal cord and the dorsal median septum (Fig. 2). By birth, the spinal cord was essentially immuno-negative for this IFAP. Thus, IFAP-300kD appears to be another differentiation marker available for future studies of gliogenesis, especially for the early stages of radial glia differentiation.


Pain ◽  
2006 ◽  
Vol 123 (3) ◽  
pp. 322-331 ◽  
Author(s):  
Takeshi Tsuji ◽  
Koji Inui ◽  
Seiji Kojima ◽  
Ryusuke Kakigi

Author(s):  
Lattimore Madison Michael ◽  
Vincent Nguyen ◽  
Jaafar Basma ◽  
William Mangham ◽  
Nickalus Khan ◽  
...  

Abstract Objectives This study was aimed to describe a far lateral approach for microsurgical resection of a transverse ligament cyst, with emphasis on the microsurgical anatomy and technique. Design A far lateral craniotomy is performed in the lateral decubitus position. After opening the dura laterally, dural sutures are placed for retraction. A stitch placed through the dentate ligament is advantageous to rotate the spinal cord to allow access to the ventral cyst. The cyst is marsupirlized and mass effect on the spinal cord is relieved. Photographs of the region are borrowed from Dr Rhoton's laboratory to illustrate the microsurgical anatomy. Participants The first author performed the surgery and edited the video. Chart review and literature review were performed by the other authors. Outcome Measures Outcome was assessed with postoperative neurological function. Results The patient was discharged home after an uneventful hospital course. At short-term follow-up, the patient had a significant improvement in postoperative strength. Conclusion The far lateral approach provides an adequate corridor to the ventrolateral brainstem in combination with utilization of the dentate ligament to reach ventral cysts compressing the spinal cord. An adequate understanding of the relevant microsurgical anatomy is a key to safe surgery in this region.The link to the video can be found at: https://youtu.be/5MGVPO2Q2pI.


2002 ◽  
Vol 22 (4) ◽  
pp. 269-274 ◽  
Author(s):  
Tameko Kihira ◽  
Masaya Hironishi ◽  
Hidehiro Utunomiya ◽  
Tomoyoshi Kondo

1989 ◽  
Vol 86 (19) ◽  
pp. 7634-7638 ◽  
Author(s):  
A. Giaid ◽  
S. J. Gibson ◽  
B. N. Ibrahim ◽  
S. Legon ◽  
S. R. Bloom ◽  
...  

2015 ◽  
Vol 26 (5) ◽  
pp. 2167-2177 ◽  
Author(s):  
John Cirillo ◽  
Finnegan J. Calabro ◽  
Monica A. Perez

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