Case study: The characterization and implementation of dielectric spectroscopy (biocapacitance) for process control in a commercial GMP CHO manufacturing process

2019 ◽  
Vol 35 (3) ◽  
pp. e2782 ◽  
Author(s):  
Brandon Moore ◽  
Ryan Sanford ◽  
An Zhang
2013 ◽  
Vol 20 (3) ◽  
pp. 345-351 ◽  
Author(s):  
Cátia Panizzon Dal Curtivo ◽  
Nathália Bitencourt Funghi ◽  
Guilherme Diniz Tavares ◽  
Sávio Fujita Barbosa ◽  
Raimar Löbenberg ◽  
...  

2018 ◽  
Vol 43 (1) ◽  
pp. 61-71
Author(s):  
SAGAR SIKDER ◽  
◽  
INDRAJIT MUKHERJEE ◽  
SUBHASH CHANDRA PANJA ◽  
◽  
...  

2021 ◽  
Vol 8 (1) ◽  
pp. 1896419
Author(s):  
Muhammad Hamad Sajjad ◽  
Khawar Naeem ◽  
Muhammad Zubair ◽  
Qazi Muhammad Usman Jan ◽  
Sikandar Bilal Khattak ◽  
...  

Author(s):  
R. Ascione ◽  
W. Polini ◽  
Q. Semeraro

Many well-known approaches exist in the literature for tolerance analysis. All the methods proposed in the literature consider the dimensional and the geometric tolerances applied to some critical points (contact points among profiles belonging to couples of parts) on the surface of the assembly components. These points are generally considered uncorrelated since the nominal surface is considered. Therefore, the methods proposed in the literature do not consider the actual surface due to a manufacturing process. Every manufacturing process leaves on the surface a signature, i.e., a systematic pattern that characterizes all the features machined with that process. The aim of the present work is to investigate the effects of considering the manufacturing signature in solving a tolerance stack-up function. A case study involving three parts has been defined and solved by means of a method of the literature, the variational method, with and without considering the correlation among the points of the same surface due to the manufacturing signature. This work represents a first step toward the integration of the design and the manufacturing in a concurrent engineering approach.


1992 ◽  
Vol 30 (8) ◽  
pp. 1889-1899
Author(s):  
ROBERT P. DAVIS ◽  
WILLIAM G. FERRELL ◽  
SANKAR SENGUPTA

2012 ◽  
Vol 11 (01) ◽  
pp. 27-50 ◽  
Author(s):  
A. J. JEGADHEESON ◽  
L. KARUNAMOORTHY ◽  
N. ARUNKUMAR ◽  
A. BALAJI ◽  
M. RAJKAMAL

Evolution is "understanding and overcoming current constraints in small steps toward optimum." "Understanding" requires elucidation of facts and corroborating theories that can explain those facts in a coherent manner. "Overcoming" requires self-development to suit the environment. In this paper, a case study about how a manufacturing process is improved in terms of productivity and quality using evolutionary improvements is explained. Here "Understanding" is achieved through use of Shainin Technique, PM analysis, Affinity Diagram, and the engineer's ingenuity, along with Relations diagram. "Overcoming" is achieved through Geometrical Analysis and Designed Experiments. The Study has set a new benchmark in the Stator riveting process by proving it can yield the desired results, and the need to adapt welding process is avoided.


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