Case Study: An accelerated 8-day monoclonal antibody production process based on high seeding densities

Ishai Padawer; Wai Lam W. Ling; Yunling Bai

doi:10.1002/btpr.1719

Case Study: An accelerated 8-day monoclonal antibody production process based on high seeding densities

Biotechnology Progress ◽

10.1002/btpr.1719 ◽

2013 ◽

Vol 29 (3) ◽

pp. 829-832 ◽

Cited By ~ 20

Author(s):

Ishai Padawer ◽

Wai Lam W. Ling ◽

Yunling Bai

Keyword(s):

Monoclonal Antibody ◽

Production Process ◽

Antibody Production ◽

Monoclonal Antibody Production

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Model-Based Monitoring and Control of a Monoclonal Antibody Production Process

Animal Cell Technology: Developments Towards the 21st Century ◽

10.1007/978-94-011-0437-1_104 ◽

1995 ◽

pp. 665-670

Author(s):

R. K. Biener ◽

W. Waldraff ◽

E. D. Gilles ◽

J. Haas ◽

W. NoÉ ◽

...

Keyword(s):

Monoclonal Antibody ◽

Production Process ◽

Antibody Production ◽

Monitoring And Control ◽

Monoclonal Antibody Production ◽

Model Based ◽

And Control

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Scale-up considerations for monoclonal antibody production process: an oxygen transfer flux approach

BMC Proceedings ◽

10.1186/1753-6561-7-s6-p49 ◽

2013 ◽

Vol 7 (S6) ◽

Cited By ~ 1

Author(s):

Laura Gimenez ◽

Claire Simonet ◽

Laetitia Malphettes

Keyword(s):

Monoclonal Antibody ◽

Production Process ◽

Antibody Production ◽

Oxygen Transfer ◽

Scale Up ◽

Monoclonal Antibody Production

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Design and operation of a continuous integrated monoclonal antibody production process

Biotechnology Progress ◽

10.1002/btpr.2522 ◽

2017 ◽

Vol 33 (5) ◽

pp. 1303-1313 ◽

Cited By ~ 43

Author(s):

Fabian Steinebach ◽

Nicole Ulmer ◽

Moritz Wolf ◽

Lara Decker ◽

Veronika Schneider ◽

...

Keyword(s):

Monoclonal Antibody ◽

Production Process ◽

Antibody Production ◽

Monoclonal Antibody Production

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Neural Network to Understand Process Capability and Process Intermediates Acceptance Criteria in Monoclonal Antibody Production Process

Journal of Pharmaceutical Innovation ◽

10.1007/s12247-017-9301-1 ◽

2017 ◽

Vol 13 (1) ◽

pp. 36-47 ◽

Cited By ~ 1

Author(s):

Ying Fei Li ◽

Venkat Venkatasubramanian

Keyword(s):

Neural Network ◽

Monoclonal Antibody ◽

Production Process ◽

Antibody Production ◽

Process Capability ◽

Acceptance Criteria ◽

Monoclonal Antibody Production

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Predictive macroscopic modeling of cell growth, metabolism and monoclonal antibody production: Case study of a CHO fed-batch production

Metabolic Engineering ◽

10.1016/j.ymben.2021.04.004 ◽

2021 ◽

Author(s):

Bassem Ben Yahia ◽

Laetitia Malphettes ◽

Elmar Heinzle

Keyword(s):

Monoclonal Antibody ◽

Cell Growth ◽

Antibody Production ◽

Fed Batch ◽

Batch Production ◽

Monoclonal Antibody Production ◽

Macroscopic Modeling ◽

Growth Metabolism

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An empirical modeling platform to evaluate the relative control discrete CHO cell synthetic processes exert over recombinant monoclonal antibody production process titer

Biotechnology and Bioengineering ◽

10.1002/bit.23146 ◽

2011 ◽

Vol 108 (9) ◽

pp. 2193-2204 ◽

Cited By ~ 15

Author(s):

Jane McLeod ◽

Peter M. O'Callaghan ◽

Leon P. Pybus ◽

Stephen J. Wilkinson ◽

Tracy Root ◽

...

Keyword(s):

Monoclonal Antibody ◽

Production Process ◽

Antibody Production ◽

Empirical Modeling ◽

Cho Cell ◽

Monoclonal Antibody Production ◽

Recombinant Monoclonal Antibody

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Energy-based culture medium design for biomanufacturing optimization: A case study in monoclonal antibody production by GS-NS0 cells

Metabolic Engineering ◽

10.1016/j.ymben.2018.02.013 ◽

2018 ◽

Vol 47 ◽

pp. 21-30 ◽

Cited By ~ 9

Author(s):

Ana L. Quiroga-Campano ◽

Nicki Panoskaltsis ◽

Athanasios Mantalaris

Keyword(s):

Monoclonal Antibody ◽

Antibody Production ◽

Culture Medium ◽

Monoclonal Antibody Production ◽

Ns0 Cells ◽

Medium Design

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Detailed Review of Monoclonal Antibody Production and Its Advantage as a Role in Malignancy and Transplant Rejection

International Journal of Scientific and Research Publications (IJSRP) ◽

10.29322/ijsrp.8.11.2018.p8337 ◽

2018 ◽

Vol 8 (11) ◽

Author(s):

Chandrasekaran M M. ◽

N. Sivakumaran

Keyword(s):

Monoclonal Antibody ◽

Antibody Production ◽

Transplant Rejection ◽

Monoclonal Antibody Production ◽

Detailed Review

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Rapamycin reduces hybridoma cell death and enhances monoclonal antibody production

Biotechnology and Bioengineering ◽

10.1002/bit.1020 ◽

2001 ◽

Vol 76 (1) ◽

pp. 1-10 ◽

Cited By ~ 40

Author(s):

R. Robert Balcarcel ◽

Gregory Stephanopoulos

Keyword(s):

Monoclonal Antibody ◽

Cell Death ◽

Antibody Production ◽

Monoclonal Antibody Production

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Purified human cytomegalovirus virion protein; useful as vaccine and for detecting CMV neutralizing antibody in serum; monoclonal antibody production

Vaccine ◽

10.1016/0264-410x(93)90085-c ◽

1993 ◽

Vol 11 (11) ◽

pp. 1167-1168

Keyword(s):

Monoclonal Antibody ◽

Human Cytomegalovirus ◽

Antibody Production ◽

Neutralizing Antibody ◽

Virion Protein ◽

Monoclonal Antibody Production

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