scholarly journals Nicotine-prevented learning and memory impairment in REM sleep-deprived rat is modulated by DREAM protein in the hippocampus

2017 ◽  
Vol 7 (6) ◽  
pp. e00704 ◽  
Author(s):  
Norlinda Abd Rashid ◽  
Hermizi Hapidin ◽  
Hasmah Abdullah ◽  
Zalina Ismail ◽  
Idris Long
Keyword(s):  
Learning And Memory ◽  
Rem Sleep ◽  
Memory Impairment ◽  
Dream Protein

Acute nicotine treatment prevents REM sleep deprivation-induced learning and memory impairment in rat

Hippocampus ◽  
2010 ◽  
pp. n/a-n/a ◽  
Author(s):  
A.M. Aleisa ◽  
G. Helal ◽  
I.A. Alhaider ◽  
K.H. Alzoubi ◽  
M. Srivareerat ◽  
...  
Keyword(s):  
Sleep Deprivation ◽  
Learning And Memory ◽  
Rem Sleep ◽  
Memory Impairment ◽  
Rem Sleep Deprivation ◽  
Nicotine Treatment

Uridine treatment prevents REM sleep deprivation-induced learning and memory impairment

2019 ◽  
Vol 148 ◽  
pp. 42-48 ◽  
Author(s):  
Busra Ocalan ◽  
Aysen Cakir ◽  
Cansu Koc ◽  
Guldal Gulec Suyen ◽  
Nevzat Kahveci
Keyword(s):  
Sleep Deprivation ◽  
Learning And Memory ◽  
Rem Sleep ◽  
Memory Impairment ◽  
Rem Sleep Deprivation

scholarly journals Ferroptosis contributes to isoflurane-induced neurotoxicity and learning and memory impairment

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Pengfei Liu ◽  
Jing Yuan ◽  
Yetong Feng ◽  
Xin Chen ◽  
Guangsuo Wang ◽  
...  
Keyword(s):  
Cell Death ◽  
Learning And Memory ◽  
Memory Impairment ◽  
Close Association ◽  
Dimethyl Fumarate ◽  
Dependent Manner ◽  
Transport Chain ◽  
The Relationship

AbstractFerroptosis is a novel type of programmed cell death, which is different from apoptosis and autophagic cell death. Recently, ferroptosis has been indicated to contribute to the in vitro neurotoxicity induced by isoflurane, which is one of the most common anesthetics in clinic. However, the in vivo position of ferroptosis in isoflurane-induced neurotoxicity as well as learning and memory impairment remains unclear. In this study, we mainly explored the relationship between ferroptosis and isoflurane-induced learning and memory, as well as the therapeutic methods in mouse model. Our results indicated that isoflurane induced the ferroptosis in a dose-dependent and time-dependent manner in hippocampus, the organ related with learning and memory ability. In addition, the activity of cytochrome c oxidase/Complex IV in mitochondrial electron transport chain (ETC) was increased by isoflurane, which might further contributed to cysteine deprivation-induced ferroptosis caused by isoflurane exposure. More importantly, isoflurane-induced ferroptosis could be rescued by both ferroptosis inhibitor (ferrostatin-1) and mitochondria activator (dimethyl fumarate), which also showed effective therapeutic action against isoflurane-induced learning and memory impairment. Taken together, our data indicate the close association among ferroptosis, mitochondria and isoflurane, and provide a novel insight into the therapy mode against isoflurane-induced learning and memory impairment.

REM Sleep Deprivation Impairs Learning and Memory by Decreasing Brain O-GlcNAc Cycling in Mouse

2021 ◽  
Author(s):  
Sang-Min Kim ◽  
Seungjae Zhang ◽  
Jiwon Park ◽  
Hyun Jae Sung ◽  
Thuy-Duong Thi Tran ◽  
...  
Keyword(s):  
Sleep Deprivation ◽  
Learning And Memory ◽  
Rem Sleep ◽  
Rem Sleep Deprivation

Effects of repeated administration of (−)-nicotine on AF64A-induced learning and memory impairment in rats

2002 ◽  
Vol 109 (3) ◽  
pp. 361-375 ◽  
Author(s):  
M. Hiramatsu ◽  
T. Yamatsu ◽  
T. Kameyama ◽  
T. Nabeshima
Keyword(s):  
Learning And Memory ◽  
Memory Impairment ◽  
Repeated Administration
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