scholarly journals Does cerebral lateralization develop? A study using functional transcranial Doppler ultrasound assessing lateralization for language production and visuospatial memory

2012 ◽  
Vol 2 (3) ◽  
pp. 256-269 ◽  
Author(s):  
Margriet A. Groen ◽  
Andrew J. O. Whitehouse ◽  
Nicholas A. Badcock ◽  
Dorothy V. M. Bishop
2015 ◽  
Vol 8 (3) ◽  
pp. 62-73
Author(s):  
Yu.V. Mikadze ◽  
M.D. Bogdanova ◽  
E.S. Lysenko ◽  
A.R. Shakhnovich ◽  
S.M. Abuzaid

There are the preliminary results of the research of interhemispheric asymmetry of cerebral hemodynamics during the performance of auditory-verbal and visual memory tasks with the use of functional transcranial doppler ultrasound (fTCD). The fTCD is considered as a non-invasive and objective method for assessment the dominant hemisphere for verbal functions. The aim of two experiments was to analyze the effect of a) different types of verbal and nonverbal tasks and b) the conditions of the mnestic activity performance (memorize and recognize) on the changes of blood flow velocity in left and right hemispheres in 62 healthy subjects. There are preliminary results of possible application fTCD to identify the dominant hemisphere for speech functions with combination of concrete verbal cognitive tasks and condition of its presentation.


2020 ◽  
Author(s):  
Marietta Papadatou-Pastou ◽  
Panagiotis Sampanis ◽  
Ioannis Koumzis ◽  
Sofia Stefanopoulou ◽  
Dionysia Sousani ◽  
...  

AbstractThe cerebral lateralization of written language has received very limited research attention in comparison to the wealth of studies on the cerebral lateralization of oral language. The purpose of the present study was thus to further our understanding of written language lateralization, by elucidating on the relative contribution of language and motor areas. This was achieved by comparing written word generation with a writing task that has similar visuomotor demands, but does not include language (i.e., the repeated drawing of symbols). We assessed cerebral laterality in 54 left- and right-handed participants by means of functional transcranial Doppler ultrasound (fTCD), a non-invasive, perfusion-sensitive neuroimaging technique. Our findings suggest that, in right-handers, the linguistic aspect of the written word generation task recruited left-hemispheric areas during writing, similarly to oral language production. In left-handers, we failed to observe the same effect, possibly due to the great variability in cerebral laterality patterns within this group or alternatively due to the attentional demands of the symbol copying task. Future work could investigate such demands using both simple and complex stimuli in the copying condition.


2017 ◽  
Vol 15 (4) ◽  
pp. 407-432 ◽  
Author(s):  
Danai Kondyli ◽  
Daphnee Stathopoulou ◽  
Nicholas A. Badcock ◽  
Marietta Papadatou-Pastou

The cerebral lateralization of language has attracted great research interest. Nevertheless, the bulk of the work focuses on language production and comprehension; research on cerebral lateralization during writing is limited. The present study assessed cerebral lateralization in 60 participants (mean age = 26.65 years, SD = 6.05, range = 20-44), 30 right-handers (14 men) and 30 left-handers (16 men), during written language production by means of functional transcranial Doppler ultrasonography (fTCD) for the first time. Findings show that left-hemispheric lateralization is observed during silent word production, for both left- and right-handers. However, during written word production, the degree of typical (left) hemispheric lateralization was significantly increased for right-handers, while left-handers presented atypical (right) hemispheric lateralization. Importantly, the difference between silent and written word generation was significantly higher in left- compared to right-handers. No main effect of sex or interactions with sex were observed. Findings suggest that a wider network of right-hemispheric areas is used during writing in left-handers. Thus, the known differences in cerebral lateralization between right- and left-handers are stronger during written language production. However, the relative contribution of language and motor areas needs to be further elucidated.


2021 ◽  
pp. 154431672110023
Author(s):  
Winnie Nguyen ◽  
Tammy Albanese ◽  
Vanessa Tran ◽  
Anne Moore ◽  
Laligam Sekhar

This is a case report of a 35-year-old female pedestrian struck by a semi-truck. computed tomographic angiography (CTA) revealed a pseudoaneurysm at the proximal brachiocephalic artery measuring 1.8 cm in cranio-caudal length and 1.2 × 0.6 cm transverse. Just distal to the pseudoaneurysm, there was severe luminal narrowing caused by either a dissection flap or mural thrombus. Due to profound left-sided weakness, transcranial Doppler ultrasound was performed which demonstrated “hesitant” waveforms in the right middle cerebral and right vertebral arteries secondary to proximal obstruction. Hesitant waveforms display mid-systolic velocity deceleration and may also be referred to as the “bunny” waveform. Emboli monitoring of the right middle cerebral and basilar arteries were positive for active embolization


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