scholarly journals Association between antiepileptic drugs and hepatocellular carcinoma in patients with epilepsy: a population‐based case–control study

2016 ◽  
Vol 6 (11) ◽  
Author(s):  
Dong‐Zong Hung ◽  
Cheng‐Li Lin ◽  
Yi‐Wen Li ◽  
Yen‐Ning Lin ◽  
Ying‐Ray Lee ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Antiepileptic Drugs ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Patients With Epilepsy ◽  
Control Study

scholarly journals Differences in associations of antiepileptic drugs and hospitalization due to hyponatremia: A population–based case–control study

Seizure ◽  
2018 ◽  
Vol 59 ◽  
pp. 28-33 ◽  
Author(s):  
Henrik Falhammar ◽  
Jonatan D. Lindh ◽  
Jan Calissendorff ◽  
Shermineh Farmand ◽  
Jakob Skov ◽  
...  
Keyword(s):  
Antiepileptic Drugs ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Control Study

Use of antiepileptic drugs and risk of fractures: Case-control study among patients with epilepsy

Neurology ◽  
2006 ◽  
Vol 66 (9) ◽  
pp. 1318-1324 ◽  
Author(s):  
P. C. Souverein ◽  
D. J. Webb ◽  
J. G. Weil ◽  
T. P. Van Staa ◽  
A.C.G. Egberts
Keyword(s):  
Antiepileptic Drugs ◽  
Case Control Study ◽  
Case Control ◽  
Patients With Epilepsy ◽  
Control Study

SSRIs associated with decreased risk of hepatocellular carcinoma: A population-based case-control study

2017 ◽  
Vol 27 (1) ◽  
pp. 187-192 ◽  
Author(s):  
Hsiang-Lin Chan ◽  
Wei-Che Chiu ◽  
Vincent Chin-Hung Chen ◽  
Kuo-You Huang ◽  
Tsu-Nai Wang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Control Study

scholarly journals Risk of ischaemic stroke associated with antiepileptic drugs: a population-based case-control study in Catalonia

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Maria Giner-Soriano ◽  
Josep Ramon Marsal ◽  
Ainhoa Gomez-Lumbreras ◽  
Rosa Morros
Keyword(s):  
Valproic Acid ◽  
Ischaemic Stroke ◽  
Antiepileptic Drugs ◽  
Drug Exposure ◽  
Case Control Study ◽  
Cerebrovascular Disorders ◽  
Population Based ◽  
Case Control ◽  
Control Study ◽  
Current Exposure

Abstract Background Cerebrovascular disorders have occurred more frequently in some Central Nervous System (CNS) disorders, such as epilepsy. Some CNS drugs have been associated with increased stroke risk. Our aim was to estimate the risk of ischaemic stroke in patients exposed to antiepileptic drugs (AED). Methods Population-based matched case-control study using SIDIAP database, based in electronic health records from primary healthcare from Catalonia, Spain. Cases were those patients with a registered diagnosis of first stroke during 2009–2014. Up to 10 controls were selected for each case and matched by sex, age, and geographic area and without a prior diagnosis of stroke. We considered global drug exposure to AED, past and current exposure and exposure in monotherapy to each AED. Results 2,865 cases and 19,406 controls were exposed to AED during the study period. Global exposure to levetiracetam [(ORadj3.3, CI95 % 2.8-4.0)], phenytoin [ORadj1.5, CI95 % 1.2–41.9)], and valproic acid [(ORadj 1.3, CI95 % 1.1–1.6)], showed significantly association to ischaemic stroke that was also maintained with current exposure of levetiracetam [ORadj4.1, CI95 % 3.3–5.2)] and valproic acid [ORadj1.4, CI95 % 1.1–1.9)]. Current levetiracetam monotherapy showed a very high risk of ischaemic stroke [(ORadj 5.1, CI95 % 3.7–6.9)]. Conclusions Drugs used for other conditions than epilepsy (pregabalin, gabapentin) were the most used AED and both did not show a risk. Levetiracetam shows a risk for stroke even when assessed in current monotherapy. The lack of data regarding the link with diagnosis and severity in our study makes it necessary to conduct further studies to confirm or dismiss our results, focussing on levetiracetam.

535: Population-Based Case-Control Study of PSA and DRE Screening on Prostate Cancer Mortality

2005 ◽  
Vol 173 (4S) ◽  
pp. 146-146
Author(s):  
Eric J. Bergstralh ◽  
Rosebud O. Roberts ◽  
Michael M. Lieber ◽  
Sara A. Farmer ◽  
Jeffrey M. Slezak ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Mortality ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Prostate Cancer Mortality ◽  
Control Study
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