scholarly journals Illness perception characteristics and influencing factors in adult patients with myasthenia gravis in China

2021 ◽  
Author(s):  
Le Xu ◽  
Xia Wang ◽  
Yafeng Cui ◽  
Yanghua Tian ◽  
Nong Zhou ◽  
...  
Keyword(s):  
Myasthenia Gravis ◽  
Influencing Factors ◽  
Illness Perception ◽  
Adult Patients

Complement C3 polymorphism is associated with the susceptibility of myasthenia gravis in Chinese adult patients

2021 ◽  
Vol 353 ◽  
pp. 577487
Author(s):  
Yao-Xian Yue ◽  
Xiang Gao ◽  
Tian-Ping Tang ◽  
Yanchen Xie ◽  
Chuan-Kai Gu ◽  
...  
Keyword(s):  
Myasthenia Gravis ◽  
Adult Patients ◽  
Complement C3 ◽  
Chinese Adult

Multiple Langerhans Cell Nodules in an Incidental Thymectomy

2003 ◽  
Vol 127 (2) ◽  
pp. 218-220
Author(s):  
Lea Novak ◽  
Claudia Y. Castro ◽  
Catherine M. Listinsky
Keyword(s):  
Cardiac Surgery ◽  
Myasthenia Gravis ◽  
Tetralogy Of Fallot ◽  
Langerhans Cells ◽  
Langerhans Cell Histiocytosis ◽  
Langerhans Cell ◽  
Surgical Correction ◽  
Adult Patients ◽  
Infants And Children

Abstract The isolated appearance of Langerhans cell histiocytosis in the thymus is quite rare. We report the finding of multiple small Langerhans cell nodules in the thymus of an 11-month-old infant who had undergone thymectomy in the course of surgical correction of tetralogy of Fallot. The subtle appearance of some of these nodules and aggregates was unlike the pattern of massive thymic infiltration seen in 7 previously reported cases of thymic Langerhans cell histiocytosis in childhood. This difference led us to consider whether these aggregates might be common in the thymus but overlooked in thymus glands removed incidental to cardiac surgery. We examined histologic material from 22 sequential thymectomy specimens removed during cardiac surgery from infants and children. None (0/22) had cohesive aggregates of Langerhans cells, as were seen in the index patient's thymus. Our patient's small thymic nodules resemble more closely a pattern found in adult patients with myasthenia gravis who have been incidentally shown to have Langerhans cell histiocytosis.

Clinical Features Of Ocular Myasthenia Gravis In Adult Patients: Diplopia and Ophthalmoplegia

2020 ◽  
Author(s):  
Junjie Tang ◽  
Fangyuan Chen ◽  
Xiaoyong Liu ◽  
Jian Chen ◽  
Qing Zhou
Keyword(s):  
Myasthenia Gravis ◽  
Clinical Features ◽  
Case Series ◽  
Adult Patients ◽  
Lateral Rectus ◽  
Initial Symptom ◽  
Inferior Rectus ◽  
Ocular Myasthenia ◽  
Case Series Study ◽  
Ocular Myasthenia Gravis

Abstract Background: The diagnosis of ocular myasthenia gravis (OMG) in adult patients remained challenged and the characteristics of diplopia and ophthalmoplegia in OMG is unclear. Methods: Retrospective case series study of medical records of 40 adult patients diagnosed with OMG at The First Affiliated Hospital of Jinan University from June, 2016 to December, 2019, was performed to analyze the clinical features, diagnostic tests and preferential affected extraocular muscles of OMG. Results: 40 adult patients with OMG were involved and men represented 20 (50%) of cases. Mean age (±SD) among men was 49 ± 21 years (range: 19-81 years) and 40 ± 15 years (range: 21-65 years) among women. 18 patients (45.0%) were 18 to 39 years old, 12 patients (30.0%) were 40 to 59 years old, 9 patients (22.5%) were 60 to 79 years old, 1 patients (2.5%) over 80 years old. The median course of the disease among all the patients was 6 months (ranged: 1 month to 10 years). Neostigmine test was positive in 32 of 40 patients (80.0%), acetycholine receptors antibodies assay was positive in 4 of 40 patients (10.0%), Thymus CT showed abnormal findings in 5 of 40 patients (12.5%). At the first visit, 27 patients (67.5%) showed diplopia only, 9 patients (22.5%) showed ptosis only, 4 patients (10.0%) showed diplopia with ptosis. The most paralytic EOM, determined through light reflection, cover-uncover test and red glass test for patients presented with diplopia only (n=27) and diplopia with ptosis (n=9), was lateral rectus (51.6%), superior rectus (19.4%), medial rectus (12.9%), inferior rectus (9.8%), superior oblique (3.2%), inferior oblique (3.2%) in order. Conclusions: OMG mainly affected adults at the working ages. Diplopia serves as initial symptom in most adult patients with OMG and lateral rectus is most susceptible.

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