scholarly journals Longitudinal changes in brain parenchyma due to mild traumatic brain injury during the first year after injury

2021 ◽  
Author(s):  
Angela M. Muller ◽  
William J. Panenka ◽  
Rael T. Lange ◽  
Grant L. Iverson ◽  
Jeffrey R. Brubacher ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Brain Parenchyma ◽  
First Year ◽  
Longitudinal Changes

Acute and longitudinal changes in motor cortex function following mild traumatic brain injury

Brain Injury ◽  
2014 ◽  
Vol 28 (10) ◽  
pp. 1270-1276 ◽  
Author(s):  
Nick R. Miller ◽  
Alia L. Yasen ◽  
Logan F. Maynard ◽  
Li-Shan Chou ◽  
David R. Howell ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Motor Cortex ◽  
Mild Traumatic Brain Injury ◽  
Longitudinal Changes

scholarly journals With Open Eyes: Returning to an Academic Life

2017 ◽  
Vol 2 (2) ◽  
pp. 126
Author(s):  
Bonnie Lynn Nish
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Narrative Inquiry ◽  
Mild Traumatic Brain Injury ◽  
Academic Career ◽  
Writing Process ◽  
Academic Life ◽  
First Year ◽  
Writing Class ◽  
Frustration Level

When asked to find a visual expression of my writing process for a first year PhD writing class, I saw a chance to unblock whatever was making it difficult for me to write. Searching for a meaningful way into my story, my ideas were reflected back through images of eyes – the eyes of strangers, my own eyes, and finally through the eyes of those who cared about me. Four years after a Mild Traumatic Brain Injury impacted my life, I returned to pursue an academic career. Symptoms that I thought had been put to rest were once again haunting me and my frustration level was escalating. Trying to find my way back into an academic existence was not an easy journey. The visual inquiry into eyes became a door through which I was able to gain back my words. Using poetic and narrative inquiry allowed for a further opening of releasing obstructions.

Longitudinal changes in mathematical abilities and white matter following paediatric mild traumatic brain injury

Brain Injury ◽  
2015 ◽  
Vol 29 (13-14) ◽  
pp. 1701-1710 ◽  
Author(s):  
Leen Van Beek ◽  
Jolijn Vanderauwera ◽  
Pol Ghesquière ◽  
Lieven Lagae ◽  
Bert De Smedt
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
White Matter ◽  
Mild Traumatic Brain Injury ◽  
Longitudinal Changes ◽  
Mathematical Abilities

scholarly journals Stability of coping and the role of self-efficacy in the first year following mild traumatic brain injury

2017 ◽  
Vol 181 ◽  
pp. 184-190 ◽  
Author(s):  
Myrthe E. Scheenen ◽  
Harm J. van der Horn ◽  
Myrthe E. de Koning ◽  
Joukje van der Naalt ◽  
Jacoba M. Spikman
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Self Efficacy ◽  
First Year

scholarly journals Immunological context of brain injury

2021 ◽  
Vol 23 (1) ◽  
pp. 163-168
Author(s):  
N. G. Plekhova ◽  
I. V. Radkov ◽  
S. V. Zinoviev ◽  
V. B. Shumatov
Keyword(s):  
Traumatic Brain Injury ◽  
T Cells ◽  
Brain Injury ◽  
Positive Reaction ◽  
Mild Traumatic Brain Injury ◽  
Brain Parenchyma ◽  
Post Injury ◽  
Blood Leukocytes ◽  
Subsequent Decrease ◽  
The Brain

The parameters of several populations of immune cells (T cell populations, macrophage subpopulations) in peripheral blood and brain were studied in a clinically significant model of mild traumatic brain injury among rats. The population of resident cells of innate immunity of microglia and brain astrocytes with local tissue damage is involved in the implementation of the inflammatory response, it is also shown that in case of trauma, blood leukocytes can overcome the blood-brain barrier and penetrate the brain parenchyma. The methods of flow cytometry and immunofluorescence were used. An increase in the number of monocytes and neutrophils up to 1 day, after a mild traumatic brain injury (TBI) with a subsequent decrease to the end of the observation period was noticed. It was determined, that the number of CD45+ cells, CD3+T cells decreased at 1 days post-injury (dpi), and rose slightly by 14 dpi, the percentage of CD4+T cells continuously declined from 7 to 14 dpi, while the percentage of CD8+T cells increased from 7 to 14 dpi. With mild traumatic brain injury in animals, a significant (3-10 times) decrease in the number of microvessels with a positive reaction to the presence of SMI 71 on the 8th and 14th day after head injury was observed. Intensive staining of SMI 71 microvessels was sometimes observed with an increase in the area of a positive reaction. Thin positive deposits of the reaction product are observed in the brain of healthy animals around the wall of the microvessel. In the damaged brain, CD45high/CD11b+ positive macrophages of the M1 subpopulation appeared in the brain tissue on the 2nd day after TBI and a significant amount was observed on the 8-14th day. In the corpus callosum and ipsilateral region of the striatum, the content of cells expressing CD16/11b+ reached a maximum 8 days after TBI, which correlated with a decrease in the positive response to the presence of endothelial antigen SMI 71. Thus, in the acute period of mild TBI, the presence of neuroimmunopathological processes is determined in the brain, which can subsequently result to the dysregulation of neuroimmune connections.

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