Identification of amino acids in the fast atom bombardment mass spectra of peptides

1988 ◽  
Vol 16 (1-12) ◽  
pp. 155-159 ◽  
Author(s):  
Wigger Heerma ◽  
Willem Kulik
Keyword(s):  
Amino Acids ◽  
Mass Spectra ◽  
Fast Atom Bombardment

Biosynthesis of isochorismate in Klebsiella pneumoniae: origin of O-2

1991 ◽  
Vol 37 (4) ◽  
pp. 276-280 ◽  
Author(s):  
Lolita O. Zamir ◽  
Kenneth A. Devor ◽  
Roy A. Jensen ◽  
Robert Tiberio ◽  
Françoise Sauriol ◽  
...  
Keyword(s):  
Amino Acids ◽  
Natural Products ◽  
Mass Spectra ◽  
Biosynthetic Pathway ◽  
Fast Atom Bombardment ◽  
Claisen Rearrangement ◽  
Aromatic Amino Acids ◽  
Hydroxyl Group ◽  
Chorismic Acid ◽  
Important Branch

The shikimate metabolites are key precursors to a large number of natural products, including aromatic amino acids. Chorismic acid is an important branch point in the biosynthetic pathway to aromatic amino acids. Chorismic acid is also unique among natural products since it is the only compound known to undergo an enzymatic Claisen rearrangement. A metabolite of chorismic acid, isochorismic acid, first observed in Aerobacter aerogenes differs in its chemical structure by the location of the hydroxyl group and the double bonds. Isochorismic acid is a precursor to a growing number of shikimate-derived metabolites. Isochorismic acid has also been postulated to be an intermediate of m-carboxyaromatic amino acids, implying another enzymatic Claisen rearrangement. In this publication, we have isolated isochorismate synthase and found that on lyophilization the enzyme is stable for at least 6 months at −20 °C. Incubation of chorismate with this preparation in water enriched with 18O led to incorporation of one atom of 18O as proven from the fast atom bombardment mass spectra of the HPLC purified derived isochorismate. Key words: chorismate, isochorismate, rearrangement, H218O, isochorismate synthetase.

Fast atom bombardment mass spectra of Fe(CO)3R1CHCR2COR3 compounds

1988 ◽  
Vol 23 (9) ◽  
pp. 674-676 ◽  
Author(s):  
Richard D. Bowen ◽  
Timothy N. Danks ◽  
David Mitchell ◽  
Susan E. Thomas
Keyword(s):  
Mass Spectra ◽  
Fast Atom Bombardment

Evidence for a lysine-specific fragmentation in fast-atom bombardment mass spectra of peptides

1992 ◽  
Vol 6 (4) ◽  
pp. 257-264 ◽  
Author(s):  
Bradley L. Ackermann ◽  
Robert J. Barbuch ◽  
John E. Coutant ◽  
John L. Krstenansky ◽  
Thomas J. Owen
Keyword(s):  
Mass Spectra ◽  
Fast Atom Bombardment

scholarly journals Fast atom bombardment mass spectra of the .BETA.-blocker nipradilol with nitrate ester group-tandem mass spectrometry (MS/MS) and B/E constant linked scanning.

1990 ◽  
Vol 38 (12) ◽  
pp. 3389-3394 ◽  
Author(s):  
Michiaki YONEDA ◽  
Kazuo TSUJIMOTO ◽  
Mamoru OHASHI ◽  
Masami SHIRATSUCHI ◽  
Yasushi OHKAWA ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Beta Blocker ◽  
Mass Spectra ◽  
Fast Atom Bombardment ◽  
Ester Group ◽  
Tandem Mass ◽  
Nitrate Ester

Liquid secondary ion mass spectra and fast atom bombardment mass spectra of diquaternary pyridinium oxime salts

1995 ◽  
Vol 30 (2) ◽  
pp. 282-289 ◽  
Author(s):  
Gary J. Kunkel ◽  
Kenneth L. Busch ◽  
Richard Dunphy ◽  
David J. Burinsky ◽  
Ruth Barak ◽  
...  
Keyword(s):  
Mass Spectra ◽  
Fast Atom Bombardment ◽  
Secondary Ion

Differentiation of the Isomeric o-(m- and p-) Nitro-(Chloro- and Bromo-)Benzyl-2,4-(and 2,1-) Disubstituted 2-Thiocytosinium Halides by Electron Impact Ionisation and Fast Atom Bombardment Mass Spectrometry

2009 ◽  
Vol 15 (4) ◽  
pp. 497-506 ◽  
Author(s):  
Tomasz Pospieszny ◽  
Elżbieta Wyrzykiewicz
Keyword(s):  
Mass Spectrometry ◽  
Mass Spectra ◽  
Fast Atom Bombardment ◽  
Collision Induced Dissociation ◽  
Mass Measurements ◽  
Fragmentation Pathways ◽  
Mass Spectral ◽  
Fragment Ions ◽  
Accurate Mass Measurements ◽  
Impact Ionisation

Electron ionisation (EI) and fast atom bombardment (FAB) mass spectral fragmentations of nine 2,4-(and 2,1-) disubstituted o-( m- and p-)nitro-(chloro- and bromo-)-2-thiocytosinium halides are investigated. Fragmentation pathways, whose elucidation is assisted by accurate mass measurements and metastable transitions [EI-mass spectrometry (MS)], as well as FAB/collision-induced dissociation (CID) mass spectra measurements are discussed. The correlations between the abundances of the (C11H10N4SO2)+1–3; (C11H10N3SCl)+4–6 and (C11H10N3SBr)+7–9 ions and the selected fragment ions (EI-MS), as well as (C18H16N5SO4)+1–3; (C18H16N3SCl2)+4–6 and (C18H16N3SBr2) + 7–9 ions and the selected ions (C7H6NO2)+1–3; (C7H6Cl)+ 4–6; (C7H6Br)+ 7–9 (FAB-MS) are discussed. The data obtained can be used for distinguishing isomers.

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