Applicability of bioanalysis of multiple analytes in drug discovery and development: review of select case studies including assay development considerations

2006 ◽  
Vol 20 (5) ◽  
pp. 383-414 ◽  
Author(s):  
Nuggehally R. Srinivas
Keyword(s):  
Drug Discovery ◽  
Case Studies ◽  
Assay Development ◽  
Development Review ◽  
Drug Discovery And Development ◽  
Multiple Analytes

Biotech–pharma alliances: Strategies, structures and financing

10.5912/jcb91 ◽  
2004 ◽  
Vol 10 (4) ◽  
Author(s):  
Tyzoon Tyebjee ◽  
Jill Hardin
Keyword(s):  
Drug Discovery ◽  
Case Studies ◽  
Financial Instruments ◽  
Drug Discovery And Development ◽  
Development Cycle ◽  
Biotechnology Companies ◽  
Strategic Logic

The drug discovery and development industry is under intense pressure to become more efficient and develop drugs better, faster, cheaper. Consequently, pharmaceutical and biotechnology companies are entering into alliances in an effort to utilise each other's talents, exploit each other's specialisations, and create more value. In this paper, the economics of the drug discovery and development cycle are examined to identify the economic and strategic logic of the alliances. The financial instruments commonly used to structure the alliances are discussed with example case studies.

scholarly journals A Triple Helix systems perspective of UK drug discovery and development: A systematic review of REF impact case studies

2020 ◽  
pp. 095042222096934
Author(s):  
Leonard Kelleher ◽  
Anna Zecharia
Keyword(s):  
Drug Discovery ◽  
Case Studies ◽  
Strategic Alliances ◽  
Triple Helix ◽  
Systems Approach ◽  
Research Policy ◽  
Empirical Studies ◽  
Innovation System ◽  
Theory Development ◽  
Drug Discovery And Development

UK drug discovery and development is increasingly being shaped through a complex interaction of research, policy and practice. However, our understanding of this innovation system is partially due to the dearth of systems-level empirical studies and to simplistic conceptual approaches. This study uses a Triple Helix systems approach to illustrate how a novel database of Research Excellence Framework 2014 impact case studies may be used both to advance empirical understanding of UK drug discovery and development and for theory development. The authors refine the Triple Helix system by identifying relationships between its three components (academia, government and industry) and various social actors. The paper also make two contributions to practice, concerning the relative unimportance for impact generation of geographical clusters relative to strategic alliances, network linkages and knowledge spillovers, and the strong bias towards national and Anglo-American academic–practitioner linkages with few or no links to emerging knowledge economies.

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