In vitro anticomplementary activity and quality evaluation of dried blossoms of Inula nervosa Wall. from different geographical origins

2019 ◽  
Vol 33 (12) ◽  
Author(s):  
Zhiqi Wen ◽  
Wenping Huang ◽  
Wei Long ◽  
Jianping Gong ◽  
Dong Wu
Keyword(s):  
Quality Evaluation ◽  
Anticomplementary Activity

scholarly journals Quality evaluation of minoxidil topical solutions obtained from magistral pharmacies

2019 ◽  
Vol 3 (2) ◽  
pp. 30-35
Author(s):  
Karen N. Dartora ◽  
Paula C. Bona ◽  
Francielli L. Dos Santos ◽  
Paula Bianchetti ◽  
Renata Vidor Contri
Keyword(s):  
Statistical Difference ◽  
Quality Evaluation ◽  
Quality Parameters ◽  
Centrifuge Test ◽  
Test Drug ◽  
Organoleptic Properties ◽  
Industrial Sample ◽  
Drug Content ◽  
Ph Values

The objective of this study was to evaluate quality parameters of magistral topical solutions containing minoxidil (A, B and C), comparing the results with the ones obtained for the industrial formulation. Organoleptic tests, evaluation of the pH and density, centrifuge test, drug content determination, comparison of indicated dosages and in vitro follicular penetration of minoxidil were performed. Regarding the organoleptic properties, differences in color and viscosity were observed between the magistral (composed of minoxidil sulfate) and the industrial formulations (composed of minoxidil base). For pH values, the magistral solutions presented considerably more acidic pH, compared to the industrial sample. For the density test, the samples with the highest ethanol percentages (B and C) presented lower density. In the centrifuge test, none of the samples showed changes. Considering the drug content test, only the industrial sample and the magistral sample C showed drug percentage within the expected (90-110%), indicating lack of correction factor determination by the magistral pharmacies. Furthermore, it was observed that the dosage indicated by the magistral pharmacies do not correspond to the dose indicated by the industry, being significantly lower. All topical solutions tested presented hair follicle penetration of minoxildil, without statistical difference. The results indicate that there is a failure in the magistral pharmacies regarding the production and the indication of dosage of minoxidil topical solutions.

scholarly journals Quality evaluation with reference to clitoriacetal and in vitro antioxidant activities of Clitoria macrophylla root

2019 ◽  
Vol 10 (4) ◽  
pp. 169 ◽  
Author(s):  
Nijsiri Ruangrungsi ◽  
Yamon Pitakpawasutthi ◽  
Maneewan Suwatronnakorn ◽  
Somchai Issaravanich ◽  
Chanida Palanuvej
Keyword(s):  
Quality Evaluation ◽  
Antioxidant Activities

scholarly journals Eight enteric-coated 50 mg diclofenac sodium tablet formulations marketed in Saudi Arabia: in vitro quality evaluation

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Muhammad M. Hammami ◽  
Rajaa F. Hussein ◽  
Reem AlSwayeh ◽  
Syed N. Alvi
Keyword(s):  
Quality Evaluation ◽  
Diclofenac Sodium ◽  
Dissolution Profile ◽  
Disintegration Time ◽  
United States Pharmacopoeia ◽  
Weight Variation ◽  
Tablet Formulations ◽  
Enteric Coated

Abstract Objective To evaluate in vitro quality of enteric-coated 50 mg diclofenac sodium tablet formulations on Saudi market. Results A reference and seven generic (G1-7) formulations were commercially available in December 2019/January 2020 and were assessed within 25–75% of manufacture-expiration period. Weight variation (range as% difference from mean, n = 20), active substance content (ASC, mean (SD) as% difference from label, n = 20), hardness (mean (SD), n = 10), and friability (% weight loss, n = 20) were 97–103%, 102.0% (3.4%), 15.4 (1.1) kg, and 0.24%, respectively, for the reference. For G2-7, they were ≤ ±5%, 98.6% (4.0%) to 109.9% (1.8%), 11.9 (0.9) to 18.3 (0.8) kg, and ≤ 0.00 to 0.75%, respectively. G1 ASC, hardness, and friability were 111.3% (1.7%), 20.1 (1.7) kg, and 1.10%, respectively. Disintegration time (n = 6) and dissolution profile (n = 8) were also determined. No formulation disintegrated or released ˃ 0.1% of label ASC in 0.1 N HCl for 2 h. The reference disintegrated in 15:00 min:seconds and released a mean (range) of 100% (99–103%) of label ASC by 45 min in phosphate buffer (pH = 6.8). G1-7 disintegrated in 8:53 to 20:37 min:seconds and released 81% (69–90%) (G1) to 109%. Except for borderline performance of G1, all formulations passed in vitro quality tests according to United States Pharmacopoeia.

In Vitro Anticomplementary Activity of Constituents from Morinda morindoides

1995 ◽  
Vol 58 (3) ◽  
pp. 372-378 ◽  
Author(s):  
Kanyanga Cimanga ◽  
Tess De Bruyne ◽  
Aleidis Lasure ◽  
Bart Van Poel ◽  
Luc Pieters ◽  
...  
Keyword(s):  
Anticomplementary Activity ◽  
Morinda Morindoides

scholarly journals In vitro quality evaluation of leading brands of ciprofloxacin tablets available in Bangladesh

2017 ◽  
Vol 10 (1) ◽  
Author(s):  
Md. Sahab Uddin ◽  
Abdullah Al Mamun ◽  
Md. Saddam Hossain ◽  
Md. Asaduzzaman ◽  
Md. Shahid Sarwar ◽  
...  
Keyword(s):  
Quality Evaluation

scholarly journals Protein Quality Evaluation of Animal Food Proteins by <i>In-Vitro</i> Methodologies

2013 ◽  
Vol 04 (04) ◽  
pp. 376-384 ◽  
Author(s):  
Jesús Manuel Barrón-Hoyos ◽  
Adrian Rafael Archuleta ◽  
María del Refugio Falcón-Villa ◽  
Rafael Canett-Romero ◽  
Francisco Javier Cinco-Moroyoqui ◽  
...  
Keyword(s):  
Quality Evaluation ◽  
Protein Quality ◽  
Food Proteins ◽  
Animal Food

scholarly journals In-Vitro Comparative Quality Evaluation of Marketed Cefuroxime 250 mg Tablets in Bangladesh

2020 ◽  
pp. 12-15
Keyword(s):  
Quality Control ◽  
Quality Evaluation ◽  
In Vitro Release ◽  
Control Parameters ◽  
Dissolution Tests ◽  
Quality Control Parameters ◽  
Retail Outlets ◽  
Release Study ◽  
Vitro Release

The study evaluated different quality control parameters of five brands of Cefuroxime 250mg tablets which are already marketed in Bangladesh. Five brands of the drug sourced from different retail outlets to assess the quality assessment and comparison of the tablets using the in-vitro release study. The brands were subjected to various official tests including uniformity of weight, thickness test, dissolution tests, and cumulative % of drug release and friability test. This research further focuses on the requirement of manufacturers to construct quality into their products during manufacture and also sustain the built-in quality from batch to batch in line with the principles of cGMP.

In vitro anticariogenic effects of Rubus caesius extracts and their quality evaluation by HPLC-DAD-MS3 analysis

Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
DM Grochowski ◽  
A Wiater ◽  
M Pleszczyńska ◽  
M Tomczykowa ◽  
S Granica ◽  
...  
Keyword(s):  
Quality Evaluation
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