Systematic evaluation of matrix effect and cross-talk-free method for simultaneous determination of zolmitriptan andN-desmethyl zolmitriptan in human plasma: a sensitive LC-MS/MS method validation and its application to a clinical pharmacokinetic study

Bhargav Patel; B. N. Suhagia; Arvind G. Jangid; Hiren N. Mistri; Nirmal Desai

doi:10.1002/bmc.3568

Systematic evaluation of matrix effect and cross-talk-free method for simultaneous determination of zolmitriptan andN-desmethyl zolmitriptan in human plasma: a sensitive LC-MS/MS method validation and its application to a clinical pharmacokinetic study

Biomedical Chromatography ◽

10.1002/bmc.3568 ◽

2015 ◽

Vol 30 (3) ◽

pp. 447-458 ◽

Cited By ~ 2

Author(s):

Bhargav Patel ◽

B. N. Suhagia ◽

Arvind G. Jangid ◽

Hiren N. Mistri ◽

Nirmal Desai

Keyword(s):

Simultaneous Determination ◽

Human Plasma ◽

Method Validation ◽

Clinical Pharmacokinetic ◽

Cross Talk ◽

Pharmacokinetic Study ◽

Matrix Effect ◽

Systematic Evaluation

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GC–MS Simultaneous Determination of Enalapril and Enalaprilat in Human Plasma: Application to a Clinical Pharmacokinetic Study

Chromatographia ◽

10.1365/s10337-010-1744-1 ◽

2010 ◽

Vol 72 (9-10) ◽

pp. 957-962 ◽

Cited By ~ 8

Author(s):

Marios Spanakis ◽

Ioannis Niopas

Keyword(s):

Simultaneous Determination ◽

Human Plasma ◽

Clinical Pharmacokinetic ◽

Pharmacokinetic Study ◽

Enalapril And Enalaprilat

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A validated LC–MS/MS assay for the simultaneous determination of the anti-leukemic agent dasatinib and two pharmacologically active metabolites in human plasma: Application to a clinical pharmacokinetic study

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2011.09.008 ◽

2012 ◽

Vol 58 ◽

pp. 130-135 ◽

Cited By ~ 18

Author(s):

Michael T. Furlong ◽

Shruti Agrawal ◽

Dara Hawthorne ◽

Michael Lago ◽

Steve Unger ◽

...

Keyword(s):

Simultaneous Determination ◽

Human Plasma ◽

Clinical Pharmacokinetic ◽

Pharmacokinetic Study ◽

Active Metabolites ◽

Pharmacologically Active

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Highly sensitive method for the determination of JI-101, a multi-kinase inhibitor in human plasma and urine by LC-MS/MS-ESI: method validation and application to a clinical pharmacokinetic study

Biomedical Chromatography ◽

10.1002/bmc.1652 ◽

2011 ◽

Vol 26 (2) ◽

pp. 232-238 ◽

Cited By ~ 2

Author(s):

Sandeep Sharma ◽

Naveen Kumar Dubey ◽

Ashish K. Dasgupta ◽

Monashis Sahu ◽

Biju Benjamin ◽

...

Keyword(s):

Human Plasma ◽

Method Validation ◽

Clinical Pharmacokinetic ◽

Pharmacokinetic Study ◽

Kinase Inhibitor ◽

Human Plasma And Urine ◽

Highly Sensitive ◽

Sensitive Method

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Simple and sensitive LC–MS/MS method for simultaneous determination of crizotinib and its major oxidative metabolite in human plasma: Application to a clinical pharmacokinetic study

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2018.03.053 ◽

2018 ◽

Vol 155 ◽

pp. 210-215

Author(s):

Xiaoyan Qi ◽

Lin Zhao ◽

Qiuping Zhao ◽

Qiaoxia Xu

Keyword(s):

Simultaneous Determination ◽

Human Plasma ◽

Clinical Pharmacokinetic ◽

Pharmacokinetic Study

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A high‐throughput and simultaneous determination of Combretastatin A‐4 Phosphate and its metabolites in human plasma by HPLC‐MS/MS: Application to a clinical pharmacokinetic study

Biomedical Chromatography ◽

10.1002/bmc.5204 ◽

2021 ◽

Author(s):

Qizhen Wu ◽

Qian Wang ◽

Yixuan Wang ◽

Jingqiu Huang ◽

Yalin Fang ◽

...

Keyword(s):

Simultaneous Determination ◽

Human Plasma ◽

Clinical Pharmacokinetic ◽

High Throughput ◽

Pharmacokinetic Study

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LC–MS/MS method for simultaneous determination of diethylcarbamazine, albendazole and albendazole metabolites in human plasma: Application to a clinical pharmacokinetic study

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2017.12.037 ◽

2018 ◽

Vol 151 ◽

pp. 84-90 ◽

Cited By ~ 12

Author(s):

Yashpal S. Chhonker ◽

Constant Edi ◽

Daryl J. Murry

Keyword(s):

Simultaneous Determination ◽

Human Plasma ◽

Clinical Pharmacokinetic ◽

Pharmacokinetic Study

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Development and validation of samples stabilization strategy and LC-MS/MS method for simultaneous determination of clevidipine and its primary metabolite in human plasma: Application to clinical pharmacokinetic study in Chinese healthy volunteers

Journal of Chromatography B ◽

10.1016/j.jchromb.2020.122448 ◽

2020 ◽

Vol 1161 ◽

pp. 122448

Author(s):

Yujia Zhang ◽

Shunbo Zhao ◽

Huan Zhou ◽

Li Ding

Keyword(s):

Healthy Volunteers ◽

Simultaneous Determination ◽

Human Plasma ◽

Clinical Pharmacokinetic ◽

Pharmacokinetic Study ◽

Primary Metabolite ◽

Development And Validation

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Development of a highly sensitive LC–MS/MS method for simultaneous determination of rupatadine and its two active metabolites in human plasma: Application to a clinical pharmacokinetic study

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2015.03.025 ◽

2015 ◽

Vol 111 ◽

pp. 163-168 ◽

Cited By ~ 7

Author(s):

Chenglong Sun ◽

Qian Li ◽

Liping Pan ◽

Bing Liu ◽

Pan Gu ◽

...

Keyword(s):

Simultaneous Determination ◽

Human Plasma ◽

Clinical Pharmacokinetic ◽

Pharmacokinetic Study ◽

Active Metabolites ◽

Highly Sensitive

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A validated enantioselective LC–MS/MS assay for the simultaneous determination of carvedilol and its pharmacologically active 4′-hydroxyphenyl metabolite in human plasma: Application to a clinical pharmacokinetic study

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2012.05.026 ◽

2012 ◽

Vol 70 ◽

pp. 574-579 ◽

Cited By ~ 19

Author(s):

Michael T. Furlong ◽

Bing He ◽

William Mylott ◽

Song Zhao ◽

Thomas Mariannino ◽

...

Keyword(s):

Simultaneous Determination ◽

Human Plasma ◽

Clinical Pharmacokinetic ◽

Pharmacokinetic Study ◽

Pharmacologically Active

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LC–MS/MS method for simultaneous determination of ramelteon and its metabolite M‐II in human plasma: Application to a clinical pharmacokinetic study in healthy Chinese volunteers

Biomedical Chromatography ◽

10.1002/bmc.4510 ◽

2019 ◽

Vol 33 (5) ◽

pp. e4510

Author(s):

Yantong Zhu ◽

Haitao Yu ◽

Tengfei Li ◽

Duo Li ◽

Li Ding ◽

...

Keyword(s):

Simultaneous Determination ◽

Human Plasma ◽

Clinical Pharmacokinetic ◽

Pharmacokinetic Study ◽

Healthy Chinese

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