LC/ESI-MS/MS method for determination of salivary eicosapentaenoic acid concentration to arachidonic acid concentration ratio

2015 ◽  
Vol 30 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Shoujiro Ogawa ◽  
Koki Tomaru ◽  
Nagisa Matsumoto ◽  
Shui Watanabe ◽  
Tatsuya Higashi
2008 ◽  
Vol 138 (11) ◽  
pp. 2190-2197 ◽  
Author(s):  
Antje R. Weseler ◽  
Chantal E. H. Dirix ◽  
Maaike J. Bruins ◽  
Gerard Hornstra

1987 ◽  
Vol 252 (1) ◽  
pp. H14-H21 ◽  
Author(s):  
S. P. Bydlowski ◽  
R. L. Yunker ◽  
M. T. Subbiah

A systematic study of the ontogeny of aortic 6-ketoprostaglandin F1 alpha synthesis from birth to adult life and the effect of premature weaning on this process was investigated in rabbits. Prostacyclin (PGI2) synthesis by both endogenous and exogenous arachidonic acid and its relation to aortic arachidonic acid content was determined. It was found that 1) PGI2 synthesis from endogenous arachidonic acid increased with age, whereas 2) PGI2 synthesis from exogenous arachidonic acid decreased. This correlated with a decrease in the incorporation of [14C]arachidonic acid into phospholipids with age. Aortic arachidonic acid concentration did not change from birth until 3 wk of life but increased markedly by 5 wk of age. Premature weaning caused a decrease in the synthesis of aortic PGI2 and in aortic arachidonic acid concentration initially, but the changes did not persist in later life. These studies suggest that the utilization of exogenous arachidonic acid by aorta decreases after birth perhaps due to maturity of the enzyme systems that synthesize and utilize endogenous substrates.


1992 ◽  
Vol 56 (3) ◽  
pp. 467-474 ◽  
Author(s):  
M T Nakamura ◽  
A B Tang ◽  
J Villanueva ◽  
C H Halsted ◽  
S D Phinney

2003 ◽  
Vol 43 (9) ◽  
pp. 983-989 ◽  
Author(s):  
Joanne Burke ◽  
Walter K. Kraft ◽  
Howard E. Greenberg ◽  
Melanie Gleave ◽  
Giovanni M. Pitari ◽  
...  

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