Synthesis and application of a chiral ionic liquid functionalizedβ-cyclodextrin as a chiral selector in capillary electrophoresis

2013 ◽  
pp. n/a-n/a ◽  
Author(s):  
Jia Yu ◽  
Lihua Zuo ◽  
Hongjiao Liu ◽  
Lijuan Zhang ◽  
Xingjie Guo
Keyword(s):  
Ionic Liquid ◽  
Capillary Electrophoresis ◽  
Chiral Selector ◽  
Chiral Ionic Liquid

L-Histidinium Chiral Ionic Liquid Functionalized β-Cyclodextrin as Chiral Selector in Capillary Electrophoresis

2021 ◽  
Author(s):  
Xiaofei Ma ◽  
Jingtang Li ◽  
Xiaoqi Li ◽  
Zijie Feng ◽  
Xuan Yang ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Capillary Electrophoresis ◽  
Ionic Liquids ◽  
Molecular Modeling ◽  
Chiral Separation ◽  
Chiral Selector ◽  
Chiral Discrimination ◽  
Chiral Ionic Liquid ◽  
First Time ◽  
Good Agreement

Abstract Nowadays, ionic liquids (ILs) functionalized cyclodextrins (CDs) have drawn increasing attention in chiral separation. Herein, a novel β-CD derivative functionalized by L-histidinium IL, mono-6-deoxy-6-L-histidinium-β-cyclodextrin chloride (L-HMCDCl), was synthesized for the first time and utilized for enantioseparation of nefopam and chlorphenamine in capillary electrophoresis. The L-HMCDCl exhibited superior enantioselectivity compared with native β-CD. The effect of some key parameters such as chiral selector concentration, buffer pH and applied voltage on the enantioseparation was investigated in detail. In the interest of the chiral discrimination mechanism and the enhanced enantioselectivity of L-HMCDCl, molecular modeling with AutoDock was employed to study the interaction, which was in good agreement with experimental results.

Chiral separation of phenylalanine and tryptophan by capillary electrophoresis using a mixture ofβ-CD and chiral ionic liquid ([TBA] [l-ASP]) as selectors

2013 ◽  
Vol 28 (5) ◽  
pp. 610-614 ◽  
Author(s):  
Wu Yujiao ◽  
Wang Guoyan ◽  
Zhao Wenyan ◽  
Zhang Hongfen ◽  
Jing Huanwang ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Capillary Electrophoresis ◽  
Chiral Separation ◽  
Chiral Ionic Liquid

(R)‐N,N,N‐Trimethyl‐2‐Aminobutanol‐Bis(Trifluoromethane‐Sulfon)Imidate Chiral Ionic Liquid Used as Chiral Selector in HPCE, HPLC, and CGC

2006 ◽  
Vol 39 (7) ◽  
pp. 1439-1449 ◽  
Author(s):  
L. M. Yuan ◽  
Y. Han ◽  
Y. Zhou ◽  
X. Meng ◽  
Z. Y. Li ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Chiral Selector ◽  
Chiral Ionic Liquid
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